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GOSSYPIN structure, CAS 652-78-8

GOSSYPIN

CAS Number652-78-8

SynonymsGossypetin 8-O-glucoside; 3,5,7,8,3',4'-hexahydroxyflavone-8-O-glucopyranoside; 3,3',4',5,7-pentahydroxyflavone-8-O-glucoside; Gossypin; Gossypetin-8-glucoside

Molecular FormulaC21H20O13

Molecular Weight480.37600

Purity

Density1.883 g/cm3

Boiling Point886ºC at 760 mmHg

Melting Point229-230ºC

Flash Point

Appearancesolid

EINECS

MSDSChineseEnglish

Symboltransportation

Signal WordWarning

Cat. No.: 2A-1170499 Purity:
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Quality Control of [ 652-78-8 ] SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number652-78-8
Catalog No.2A-1170499
Chinese NameGossypin
SynonymsGossypetin 8-O-glucoside; 3,5,7,8,3',4'-hexahydroxyflavone-8-O-glucopyranoside; 3,3',4',5,7-pentahydroxyflavone-8-O-glucoside; Gossypin; Gossypetin-8-glucoside
Molecular FormulaC21H20O13
Molecular Weight480.37600
Density1.883 g/cm3
Boiling Point886ºC at 760 mmHg
Melting Point229-230ºC
Appearancesolid
Storage Conditionroom temperature
ApplicationGossypin is a flavonoid isolated from Hibiscus vitifolius and has antioxidant, anti-inflammatory, anti-cancer, anti-aging, anti-diabetic, analgesic and hepatoprotective activities. Gossypin inhibits N
PubChem ID12237
SMILESO=c1c(O)c(-c2ccc(O)c(O)c2)oc2c(OC3OC(CO)C(O)C(O)C3O)c(O)cc(O)c12
InChIInChI=1S/C21H20O13/c22-5-11-13(27)15(29)17(31)21(32-11)34-19-10(26)4-9(25)12-14(28)16(30)18(33-20(12)19)6-1-2-7(23)8(24)3-6/h1-4,11,13,15,17,21-27,29-31H,5H2/t11-,13-,15+,17-,21+/m1/s1
InChI KeySJRXVLUZMMDCNG-KKPQBLLMSA-N
Hazard Symbolstransportation
BioactivityGossypin is a flavone isolated from Hibiscus vitifolius and has antioxidant, antiinflammatory, anticancer, anticataract, antidiabetic, analgesic and hepatoprotective activities. Gossypin inhibits NF-κB and NF-κB-regulated gene expression. Gossypin inhibits RANKL-induced osteoclastogenesis both in mouse primary bone marrow cells and RAW 264.7 cells in vitro[1][2]. Related Catalog Research Areas >> Cancer Research Areas >> Cardiovascular Disease Research Areas >> Inflammation/Immunology Target IC50: NF-κB[1] References [1]. Ajaikumar B Kunnumakkara, et al. Gossypin, a pentahydroxy glucosyl flavone, inhibits the transforming growth factor beta-activated kinase-1-mediated NF-kappaB activation pathway, leading to potentiation of apoptosis, suppression of invasion, and abrogation of osteoclastogenesis. Blood. 2007 Jun 15;109(12):5112-21. [2]. Kanika Patel, et al. Gossypin: A phytochemical of multispectrum potential. the Journal of Coastal Life Medicine. Chemical & Physical Properties Density 1.883 g/cm3 Boiling Point 886ºC at 760 mmHg Melting Point 229-230ºC Molecular Formula C21H20O13 Molecular Weight 480.37600 Flash Point 310.8ºC Exact Mass 480.09000 PSA 230.74000 Index of Refraction 1.799 InChIKey SJRXVLUZMMDCNG-KKPQBLLMSA-N SMILES O=c1c(O)c(-c2ccc(O)c(O)c2)oc2c(OC3OC(CO)C(O)C(O)C3O)c(O)cc(O)c12
Use ofProperties Name gossypin Synonym More Synonyms Gossypin Biological Activity Related Catalog Research Areas >> Cancer Research Areas >> Cardiovascular Disease Research Areas >> Inflammation/Immunology IC50: NF-κB[1] References [1]. Ajaikumar B Kunnumakkara, et al. Gossypin, a pentahydroxy glucosyl flavone, inhibits the transforming growth factor beta-activated kinase-1-mediated NF-kappaB activation pathway, leading to potentiation of apoptosis, suppression of invasion, and abrogation of osteoclastogenesis. Blood. 2007 Jun 15;109(12):5112-21. [2]. Kanika Patel, et al. Gossypin: A phytochemical of multispectrum potential. the Journal of Coastal Life Medicine. Chemical & Physical Properties Molecular Formula C21H20O13 Exact Mass 480.09000 PSA 230.74000 Index of Refraction 1.799 InChIKey SJRXVLUZMMDCNG-KKPQBLLMSA-N
Transport InfoShipping Name: UN
MSDS Transport InfoModule 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available
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