CAS Number955365-80-7
Synonyms2-allyl-1,8-dimethoxy-9,10-anthraquinone; 9,10-Anthracenedione,1,8-dimethoxy-2-(2-propenyl); 2-allyl-1,8-dimethoxyanthracene-9,10-dione; MK-1775; MK1775; AZD1775
Molecular FormulaC27H32N8O2
Molecular Weight500.595
Density1.3±0.1 g/cm3
Boiling Point723.8±70.0 °C at 760 mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 955365-80-7 |
| Catalog No. | 2A-1170345 |
| Chinese Name | Adavosertib (MK-1775) |
| Synonyms | 2-allyl-1,8-dimethoxy-9,10-anthraquinone; 9,10-Anthracenedione,1,8-dimethoxy-2-(2-propenyl); 2-allyl-1,8-dimethoxyanthracene-9,10-dione; MK-1775; MK1775; AZD1775 |
| Molecular Formula | C27H32N8O2 |
| Molecular Weight | 500.595 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 723.8±70.0 °C at 760 mmHg |
| Storage Condition | Room temperature, dry, sealed |
| Application | Adavosertib (AZD-1775; MK-1775) is a potent Wee1 inhibitor with an IC50 of 5.2 nM. |
| PubChem ID | 50087297 |
| SMILES | C=CCn1c(=O)c2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc2n1-c1cccc(C(C)(C)O)n1 |
| InChI | InChI=1S/C27H32N8O2/c1-5-13-34-25(36)21-18-28-26(29-19-9-11-20(12-10-19)33-16-14-32(4)15-17-33)31-24(21)35(34)23-8-6-7-22(30-23)27(2,3)37/h5-12,18,37H,1,13-17H2,2-4H3,(H,28,29,31) |
| InChI Key | BKWJAKQVGHWELA-UHFFFAOYSA-N |
| Transport Info | Product name: MK-1775 |
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