
CAS Number332012-40-5
SynonymsTelatinib,BAY 57-9352,BAY 57-9352; S2231_Selleck; BAY57-9352; Telatinib; 4-[({4-[(4-Chlorophenyl)amino]furo[2,3-d]pyridazin-7-yl}oxy)methyl]-N-methyl-2-pyridinecarboxamide; Bay 57-9352; UNII:18P7197Q7J; 4-(4-chlorophenylamino)-7-(2-methylaminocarbonyl-4-pyridylmethoxy)furo-[2,3-d]pyridazine; 4-((4-(4-chlorophenylamino)furo[2,3-d]pyridazin-7-yloxy)methyl)-N-methylpicolinamide; BAY-579352
Molecular FormulaC20H16ClN5O3
Molecular Weight409.826
Density1.4±0.1 g/cm3
Boiling Point713.6±60.0 °C at 760 mmHg
Appearancepowder
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 332012-40-5 |
| Catalog No. | 2A-1170282 |
| Chinese Name | 替拉替尼 |
| Synonyms | Telatinib,BAY 57-9352,BAY 57-9352; S2231_Selleck; BAY57-9352; Telatinib; 4-[({4-[(4-Chlorophenyl)amino]furo[2,3-d]pyridazin-7-yl}oxy)methyl]-N-methyl-2-pyridinecarboxamide; Bay 57-9352; UNII:18P7197Q7J; 4-(4-chlorophenylamino)-7-(2-methylaminocarbonyl-4-pyridylmethoxy)furo-[2,3-d]pyridazine; 4-((4-(4-chlorophenylamino)furo[2,3-d]pyridazin-7-yloxy)methyl)-N-methylpicolinamide; BAY-579352 |
| Molecular Formula | C20H16ClN5O3 |
| Molecular Weight | 409.826 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 713.6±60.0 °C at 760 mmHg |
| Appearance | powder |
| Storage Condition | -20℃ |
| Application | Telatinib is an orally active small molecule inhibitor of VEGFR2, VEGFR3, PDGFα and c-Kit, with IC50 values of 6, 4, 15 and 1 nM respectively. |
| PubChem ID | 14831018 |
| SMILES | CNC(=O)c1cc(COc2nnc(Nc3ccc(Cl)cc3)c3ccoc23)ccn1 |
| InChI | InChI=1S/C20H16ClN5O3/c1-22-19(27)16-10-12(6-8-23-16)11-29-20-17-15(7-9-28-17)18(25-26-20)24-14-4-2-13(21)3-5-14/h2-10H,11H2,1H3,(H,22,27)(H,24,25) |
| InChI Key | QFCXANHHBCGMAS-UHFFFAOYSA-N |
| Transport Info | Product Name: Telatinib |
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