CAS Number73-48-3
SynonymsPluryl; benzoflumethiazide; 3-Benzyl-6-(trifluorométhyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxyde; Bendrofluazide; Naturetin; 3,4-Dihydro-3-(phenylmethyl)-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide; 3-Benzyl-3,4-dihydro-7-sulfamyl-6-trifluoromethyl-1,2,4-benzothiadiazine 1,1-Dioxide; 3-Benzyl-6-(trifluoromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide; Benzydroflumethiazide; Centyl; Benzylrodiuran; Berkozide; bendroflumethiazide; bendroflumethazide; Neo-naclex; Naturine; 3-(Phenylmethyl)-6-(trifluoromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide; bendroflumetazide; Aprinox; T66 BSWM EM DHJ D1R& HXFFF ISZW; Salures
Molecular FormulaC15H14F3N3O4S2
Molecular Weight319.28
Purity98.00%
Density1.5±0.1 g/cm3
Boiling Point602.1±65.0 °C at 760 mmHg
Melting Point205-207ºC
Appearancewhite solid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 73-48-3 |
| Catalog No. | 2A-9017042 |
| Chinese Name | 苄氟噻嗪 |
| Synonyms | Pluryl; benzoflumethiazide; 3-Benzyl-6-(trifluorométhyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxyde; Bendrofluazide; Naturetin; 3,4-Dihydro-3-(phenylmethyl)-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide; 3-Benzyl-3,4-dihydro-7-sulfamyl-6-trifluoromethyl-1,2,4-benzothiadiazine 1,1-Dioxide; 3-Benzyl-6-(trifluoromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide; Benzydroflumethiazide; Centyl; Benzylrodiuran; Berkozide; bendroflumethiazide; bendroflumethazide; Neo-naclex; Naturine; 3-(Phenylmethyl)-6-(trifluoromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide; bendroflumetazide; Aprinox; T66 BSWM EM DHJ D1R& HXFFF ISZW; Salures |
| Molecular Formula | C15H14F3N3O4S2 |
| Molecular Weight | 319.28 |
| Purity | 98.00 |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 602.1±65.0 °C at 760 mmHg |
| Melting Point | 205-207ºC |
| Appearance | white solid |
| Water Solubility | Practically insoluble in water, freely soluble in |
| Storage Condition | Ventilated low-temperature drying |
| Application | Bendrocarbazine is an oral diuretic. Benzoflumethiazide is an antihypertensive drug. Benzoflumethiazide has potential in the study of arterial hypertension [1]. |
| PubChem ID | 329831025 |
| MDL Number | MFCD00197629 |
| SMILES | Nc1cc(c(cc1S(N)(=O)=O)S(N)(=O)=O)C(F)(F)F |
| InChI | 1S/C7H8F3N3O4S2/c8-7(9,10)3-1-4(11)6(19(13,16)17)2-5(3)18(12,14)15/h1-2H,11H2,(H2,12,14,15)(H2,13,16,17) |
| InChI Key | KRVABEGPNKGLOT-UHFFFAOYSA-N |
| Beilstein/REAXYS | 1164542 |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/17042_1_73_48_3.pdf |
| Bioactivity | Bendroflumethiazide is an orally active diuretic. Bendroflumethiazide is an antihypertensive agent. Bendroflumethiazide has the potential for the research of arterial hypertensive disease[1]. Related Catalog Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others References [1]. GRIEBLE HG, et al. Treatment of arterial hypertensive disease with diuretics. I. Effects on blood pressure of bendroflumethiazide, potassium chloride, and spironolactone. Arch Intern Med. 1962;110:26-33. Chemical & Physical Properties Density 1.5±0.1 g/cm3 Boiling Point 602.1±65.0 °C at 760 mmHg Melting Point 205-207ºC Molecular Formula C15H14F3N3O4S2 Molecular Weight 421.415 Flash Point 318.0±34.3 °C Exact Mass 421.037781 PSA 135.12000 LogP 2.07 Vapour Pressure 0.0±1.7 mmHg at 25°C Index of Refraction 1.584 InChIKey HDWIHXWEUNVBIY-UHFFFAOYSA-N SMILES NS(=O)(=O)c1cc2c(cc1C(F)(F)F)NC(Cc1ccccc1)NS2(=O)=O Water Solubility Practically insoluble in water, freely soluble in acetone, soluble in ethanol (96 per cent). |
| Use of | Bendroflumethiazide is an orally active diuretic. Bendroflumethiazide is an antihypertensive agent. Bendroflumethiazide has the potential for the research of arterial hypertensive disease[1]. Properties Articles28 Name bendroflumethiazide Synonym More Synonyms bendroflumethiazide Biological Activity Description Bendroflumethiazide is an orally active diuretic. Bendroflumethiazide is an antihypertensive agent. Bendroflumethiazide has the potential for the research of arterial hypertensive disease[1]. Related Catalog Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others References [1]. GRIEBLE HG, et al. Treatment of arterial hypertensive disease with diuretics. I. Effects on blood pressure of bendroflumethiazide, potassium chloride, and spironolactone. Arch Intern Med. 1962;110:26-33. Chemical & Physical Properties Molecular Formula C15H14F3N3O4S2 Exact Mass 421.037781 PSA 135.12000 Index of Refraction 1.584 InChIKey HDWIHXWEUNVBIY-UHFFFAOYSA-N Water Solubility Practically insoluble in water, freely soluble in acetone, soluble in ethanol (96 per cent). |
| Transport Info | Product Name: Benzylfluthiazide |
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