CAS Number72-14-0
Synonyms2-Sulfanilamidothiazole; Sulfatiazol; Neo-Strepsan; Sulphathiazole; Norsulfazole; 4-Amino-N-(1,3-thiazol-2-yl)benzenesulfonamide; MFCD00005319; Nl-2-Thiazolylsulfanilamide; EINECS 200-771-5; 2090 R.P.; 2090 RP; M & B 760; 4-Amino-N-thiazol-2-ylidenebenzene-sulfonamide; Sulfathiazolum; 2-Sulfonamidothiazole; Sulfathiazole; Sulfanilamidothiazole
Molecular FormulaC9H9N3O2S2
Molecular Weight255.32
Purity98.00%
Density1.6±0.1 g/cm3
Boiling Point479.5±47.0 °C at 760 mmHg
Melting Point200-202 °C (lit.)
Appearancepowder
EINECS200-771-5
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 72-14-0 |
| Catalog No. | 2A-9017025 |
| Chinese Name | 磺胺噻唑 |
| Synonyms | 2-Sulfanilamidothiazole; Sulfatiazol; Neo-Strepsan; Sulphathiazole; Norsulfazole; 4-Amino-N-(1,3-thiazol-2-yl)benzenesulfonamide; MFCD00005319; Nl-2-Thiazolylsulfanilamide; EINECS 200-771-5; 2090 R.P.; 2090 RP; M & B 760; 4-Amino-N-thiazol-2-ylidenebenzene-sulfonamide; Sulfathiazolum; 2-Sulfonamidothiazole; Sulfathiazole; Sulfanilamidothiazole |
| Molecular Formula | C9H9N3O2S2 |
| Molecular Weight | 255.32 |
| Purity | 98.00 |
| Density | 1.6±0.1 g/cm3 |
| Boiling Point | 479.5±47.0 °C at 760 mmHg |
| Melting Point | 200-202 °C (lit.) |
| Appearance | powder |
| Water Solubility | Insoluble (<0.1 g/100 mL at 21 ºC) |
| Storage Condition | This product should be sealed, cool, dry and prote |
| Packaging | III |
| Application | Sulfathiazole is a short-acting sulfonamide antibiotic. |
| EINECS | 200-771-5 |
| HTC | 2935009090 |
| PubChem ID | 329824636 |
| MDL Number | MFCD00005319 |
| SMILES | Nc1ccc(cc1)S(=O)(=O)Nc2nccs2 |
| InChI | 1S/C9H9N3O2S2/c10-7-1-3-8(4-2-7)16(13,14)12-9-11-5-6-15-9/h1-6H,10H2,(H,11,12) |
| InChI Key | JNMRHUJNCSQMMB-UHFFFAOYSA-N |
| Beilstein/REAXYS | 226178 |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| Hazard Symbols | 6.1(b) |
| MSDS | msds/17025_1_72_14_0.pdf |
| Bioactivity | Sulfathiazole is an organosulfur compound that has been used as a short-acting sulfa drug.Target: AntibacterialSulfathiazole (20 μg/L) starts to be degraded between day 31 and day 38 in one of the two batch reactors containing different wastewater matrices. Sulfathiazole is degraded at a substantially faster rate than sulfamethoxazole or sulfamethazine in the nitrification process (S3) [1]. Recovery from spiked manure slurry samples is 64% for Sulfathiazole at pH 9. Sulfathiazole has acidity constant of pKa of 7.1and retention times (tR) of 7.8. S/N values for Sulfathiazole are above 100 at the 1 mg/kg level [2]. Sulfathiazole sorption to inorganic sorbents exhibits pronounced pH dependence consistent with sorbate speciation and sorbent charge properties. Sulfathiazole cations are most important for sorption to clay minerals, followed by neutral species [3]. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection Natural Products >> Alkaloid References [1]. Perez, S., P. Eichhorn, and D.S. Aga, Evaluating the biodegradability of sulfamethazine, sulfamethoxazole, sulfathiazole, and trimethoprim at different stages of sewage treatment. Environ Toxicol Chem, 2005. 24(6): p. 1361-7. [2]. Haller, M.Y., et al., Quantification of veterinary antibiotics (sulfonamides and trimethoprim) in animal manure by liquid chromatography-mass spectrometry. J Chromatogr A, 2002. 952(1-2): p. 111-20. [3]. Kahle, M. and C. Stamm, Time and pH-dependent sorption of the veterinary antimicrobial sulfathiazole to clay minerals and ferrihydrite. Chemosphere, 2007. 68(7): p. 1224-31. Chemical & Physical Properties Density 1.6±0.1 g/cm3 Boiling Point 479.5±47.0 °C at 760 mmHg Melting Point 202.5ºC Molecular Formula C9H9N3O2S2 Molecular Weight 255.317 Flash Point 243.8±29.3 °C Exact Mass 255.013611 PSA 121.70000 LogP 0.05 Vapour Pressure 0.0±1.2 mmHg at 25°C Index of Refraction 1.704 InChIKey JNMRHUJNCSQMMB-UHFFFAOYSA-N SMILES Nc1ccc(S(=O)(=O)Nc2nccs2)cc1 Storage condition 0-6°C Stability Stable. Incompatible with strong oxidizing agents. Water Solubility Insoluble (<0.1 g/100 mL at 21 ºC) |
| Use of | Properties Articles40 Name sulfathiazole Synonym More Synonyms Sulfathiazole Biological Activity Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection Natural Products >> Alkaloid References [1]. Perez, S., P. Eichhorn, and D.S. Aga, Evaluating the biodegradability of sulfamethazine, sulfamethoxazole, sulfathiazole, and trimethoprim at different stages of sewage treatment. Environ Toxicol Chem, 2005. 24(6): p. 1361-7. [2]. Haller, M.Y., et al., Quantification of veterinary antibiotics (sulfonamides and trimethoprim) in animal manure by liquid chromatography-mass spectrometry. J Chromatogr A, 2002. 952(1-2): p. 111-20. [3]. Kahle, M. and C. Stamm, Time and pH-dependent sorption of the veterinary antimicrobial sulfathiazole to clay minerals and ferrihydrite. Chemosphere, 2007. 68(7): p. 1224-31. Chemical & Physical Properties Molecular Formula C9H9N3O2S2 Exact Mass 255.013611 PSA 121.70000 Index of Refraction 1.704 InChIKey JNMRHUJNCSQMMB-UHFFFAOYSA-N Stability Stable. Incompatible with strong oxidizing agents. |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 35.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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