CAS Number6515-36-2
Synonyms7-monohydroxyflavanone; 7-hydroxy-2-phenyl-4-chromanone; MFCD00017487; 7-Hydroxyflavanone,7-Hydroxy-2-phenylchroman-4-one; 7-hydroxy-flavanone; 7-HYDROXY-2-PHENYL-CHROMAN-4-ONE; 7-HYDROXY-2-PHENYLCHROMAN-4-ONE; 7-hydroxyflavan-4-one; UNII:CC64495H41; 7-HYDROXYFLAVANONE; HYDROXYFLAVANONE,7; 7-Hydroxy-2-phenyl-2,3-dihydro-4H-chromen-4-one
Molecular FormulaC15H12O3
Molecular Weight240.254
Purity98%
Density1.3±0.1 g/cm3
Boiling Point464.3±45.0 °C at 760 mmHg
Melting Point188-190 °C(lit.)
AppearanceSolid;White to Yellow to Orange powder to crystal
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 6515-36-2 |
| Catalog No. | 2A-1169890 |
| Chinese Name | 7-羟基黄烷酮 |
| Synonyms | 7-monohydroxyflavanone; 7-hydroxy-2-phenyl-4-chromanone; MFCD00017487; 7-Hydroxyflavanone,7-Hydroxy-2-phenylchroman-4-one; 7-hydroxy-flavanone; 7-HYDROXY-2-PHENYL-CHROMAN-4-ONE; 7-HYDROXY-2-PHENYLCHROMAN-4-ONE; 7-hydroxyflavan-4-one; UNII:CC64495H41; 7-HYDROXYFLAVANONE; HYDROXYFLAVANONE,7; 7-Hydroxy-2-phenyl-2,3-dihydro-4H-chromen-4-one |
| Molecular Formula | C15H12O3 |
| Molecular Weight | 240.254 |
| Purity | 98 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 464.3±45.0 °C at 760 mmHg |
| Melting Point | 188-190 °C(lit.) |
| Appearance | Solid;White to Yellow to Orange powder to crystal |
| Storage Condition | room temperature, dry |
| Application | 7-Hydroxyflavanone is an aromatase (cytochrome P450 19; CYP19) inhibitor with an IC50 of 65 μM [1]. |
| HTC | 2932999099 |
| PubChem ID | 3155459 |
| SMILES | O=C1CC(c2ccccc2)Oc2cc(O)ccc21 |
| InChI | InChI=1S/C15H12O3/c16-11-6-7-12-13(17)9-14(18-15(12)8-11)10-4-2-1-3-5-10/h1-8,14,16H,9H2 |
| InChI Key | SWAJPHCXKPCPQZ-UHFFFAOYSA-N |
| Hazard Symbols | transportation |
| Bioactivity | 7-Hydroxyflavanone is an aromatase (cytochrome P450 19; CYP19) inhibitor with an IC50 of 65 μM[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Others >> Aromatase Target IC50: 65 μM (Aromatase)[1] References [1]. Sanderson JT, et al. Induction and inhibition of aromatase (CYP19) activity by natural and synthetic flavonoid compounds in H295R human adrenocortical carcinoma cells. Toxicol Sci. 2004 Nov;82(1):70-9. Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 464.3±45.0 °C at 760 mmHg Melting Point 188-190 °C(lit.) Molecular Formula C15H12O3 Molecular Weight 240.254 Flash Point 181.2±22.2 °C Exact Mass 240.078644 PSA 46.53000 LogP 3.49 Vapour Pressure 0.0±1.2 mmHg at 25°C Index of Refraction 1.632 InChIKey SWAJPHCXKPCPQZ-UHFFFAOYSA-N SMILES O=C1CC(c2ccccc2)Oc2cc(O)ccc21 |
| Use of | 7-Hydroxyflavanone is an aromatase (cytochrome P450 19; CYP19) inhibitor with an IC50 of 65 μM[1]. Properties Name 7-hydroxyflavanone Synonym More Synonyms UNII:CC64495H41 Biological Activity Description 7-Hydroxyflavanone is an aromatase (cytochrome P450 19; CYP19) inhibitor with an IC50 of 65 μM[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Others >> Aromatase IC50: 65 μM (Aromatase)[1] References [1]. Sanderson JT, et al. Induction and inhibition of aromatase (CYP19) activity by natural and synthetic flavonoid compounds in H295R human adrenocortical carcinoma cells. Toxicol Sci. 2004 Nov;82(1):70-9. Chemical & Physical Properties Molecular Formula C15H12O3 Exact Mass 240.078644 PSA 46.53000 Index of Refraction 1.632 InChIKey SWAJPHCXKPCPQZ-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: No dangerous goods IMDG Code: No dangerous goods International Air Transport Dangerous Regulations: No dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special precautions for users No data available |
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