CAS Number51059-44-0
Synonyms5-Hydroxy-8-methoxy-4-oxo-2-phenyl-4H-chromen-7-yl β-D-glucopyranosiduronic acid; Oroxindin; Wogonin 7-β-D-glucuronide; wogonin 7-O-glucuronoside; wogonin 7-O-β-D-glucuronide; 2-C-(5-Hydroxy-8-methoxy-4-oxo-2-phenyl-4H-chromen-7-yl)-D-glucuronic acid; Wogonin-7-O-|A-D-glucuronide; Wogonoside; Wogonin 7-O-glucuronide; Glychionide B; 5,7-dihydroxy-8-methoxyflavone 7-O-β-D-glucuronide
Molecular FormulaC22H20O11
Molecular Weight460.388
Purity98%%
Density1.6±0.1 g/cm3
Boiling Point869.0±65.0 °C at 760 mmHg
Melting Point226-227ºC
AppearanceSolid;White to Orange to Green powder to crystal
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 51059-44-0 |
| Catalog No. | 2A-1169427 |
| Chinese Name | 汉黄芩苷 |
| Synonyms | 5-Hydroxy-8-methoxy-4-oxo-2-phenyl-4H-chromen-7-yl β-D-glucopyranosiduronic acid; Oroxindin; Wogonin 7-β-D-glucuronide; wogonin 7-O-glucuronoside; wogonin 7-O-β-D-glucuronide; 2-C-(5-Hydroxy-8-methoxy-4-oxo-2-phenyl-4H-chromen-7-yl)-D-glucuronic acid; Wogonin-7-O-|A-D-glucuronide; Wogonoside; Wogonin 7-O-glucuronide; Glychionide B; 5,7-dihydroxy-8-methoxyflavone 7-O-β-D-glucuronide |
| Molecular Formula | C22H20O11 |
| Molecular Weight | 460.388 |
| Purity | 98% |
| Density | 1.6±0.1 g/cm3 |
| Boiling Point | 869.0±65.0 °C at 760 mmHg |
| Melting Point | 226-227ºC |
| Appearance | Solid;White to Orange to Green powder to crystal |
| Storage Condition | ?20°C |
| Application | Wogonoside is a flavonoid glycoside compound isolated from Scutellaria baicalensis, which has anti-inflammatory effects. Wogonoside induces autophagy in breast cancer cells by regulating the MAPK-mTOR |
| SMILES | COc1c(OC2OC(C(=O)O)C(O)C(O)C2O)cc(O)c2c(=O)cc(-c3ccccc3)oc12 |
| InChI | InChI=1S/C22H20O11/c1-30-18-13(32-22-17(27)15(25)16(26)20(33-22)21(28)29)8-11(24)14-10(23)7-12(31-19(14)18)9-5-3-2-4-6-9/h2-8,15-17,20,22,24-27H,1H3,(H,28,29)/t15-,16-,17+,20-,22+/m0/s1 |
| InChI Key | LNOHXHDWGCMVCO-NTKSAMNMSA-N |
| Hazard Symbols | transportation |
| MSDS | msds/169545_2_51059_44_0.pdf |
| Bioactivity | Wogonoside, a flavonoid glycoside isolated from Huangqin, possesses anti-inflammatory effects. Wogonoside induces autophagy in breast cancer cells by regulating MAPK-mTOR pathway[1][2]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Autophagy >> Autophagy Research Areas >> Inflammation/Immunology References [1]. Yang YZ, et al. Wogonoside displays anti-inflammatory effects through modulating inflammatory mediator expression using RAW264.7 cells. J Ethnopharmacol. 2013 Jun 21;148(1):271-6. [2]. Sun Y, et al. Wogonoside induces autophagy in MDA-MB-231 cells by regulating MAPK-mTOR pathway. Food Chem Toxicol. 2013 Jan;51:53-60. Chemical & Physical Properties Density 1.6±0.1 g/cm3 Boiling Point 869.0±65.0 °C at 760 mmHg Melting Point 226-227ºC Molecular Formula C22H20O11 Molecular Weight 460.388 Flash Point 304.0±27.8 °C Exact Mass 460.100555 PSA 176.12000 LogP 1.42 Vapour Pressure 0.0±0.3 mmHg at 25°C Index of Refraction 1.685 InChIKey LNOHXHDWGCMVCO-NTKSAMNMSA-N SMILES COc1c(OC2OC(C(=O)O)C(O)C(O)C2O)cc(O)c2c(=O)cc(-c3ccccc3)oc12 Storage condition ?20°C |
| Use of | Wogonoside, a flavonoid glycoside isolated from Huangqin, possesses anti-inflammatory effects. Wogonoside induces autophagy in breast cancer cells by regulating MAPK-mTOR pathway[1][2]. Properties Articles16 Name (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(5-hydroxy-8-methoxy-4-oxo-2-phenylchromen-7-yl)oxyoxane-2-carboxylic acid Synonym More Synonyms Wogonoside Biological Activity Description Wogonoside, a flavonoid glycoside isolated from Huangqin, possesses anti-inflammatory effects. Wogonoside induces autophagy in breast cancer cells by regulating MAPK-mTOR pathway[1][2]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Autophagy >> Autophagy Research Areas >> Inflammation/Immunology References Chemical & Physical Properties Molecular Formula C22H20O11 Exact Mass 460.100555 PSA 176.12000 Index of Refraction 1.685 InChIKey LNOHXHDWGCMVCO-NTKSAMNMSA-N |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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