CAS Number213261-59-7
Synonymsp53 Activator III,RITA; (Furan-2,5-diyldithiene-5,2-diyl)dimethanol; RITA; (2,5-Furandiyldi-5,2-thienediyl)dimethanol; SOS BISMETHANOL; Reactivation of p53 and Induction of Tumor cell Apoptosis; NSC 652287; 5,5'-(2,5-Furandiyl)bis-2-thiophenemethanol; NSC652287
Molecular FormulaC14H12O3S2
Molecular Weight292.373
Density1.4±0.1 g/cm3
Boiling Point464.9±40.0 °C at 760 mmHg
Melting Point160 °C
AppearanceSolid;White to Yellow to Orange powder to crystal
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 213261-59-7 |
| Catalog No. | 2A-1169278 |
| Chinese Name | RITA |
| Synonyms | p53 Activator III,RITA; (Furan-2,5-diyldithiene-5,2-diyl)dimethanol; RITA; (2,5-Furandiyldi-5,2-thienediyl)dimethanol; SOS BISMETHANOL; Reactivation of p53 and Induction of Tumor cell Apoptosis; NSC 652287; 5,5'-(2,5-Furandiyl)bis-2-thiophenemethanol; NSC652287 |
| Molecular Formula | C14H12O3S2 |
| Molecular Weight | 292.373 |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 464.9±40.0 °C at 760 mmHg |
| Melting Point | 160 °C |
| Appearance | Solid;White to Yellow to Orange powder to crystal |
| Storage Condition | Store at -20°C |
| Application | RITA is a potent inhibitor of the p53-HDM-2 interaction, binds to p53dN with a Kd of 1.5 nM, and is able to induce DNA-DNA cross-links. |
| SMILES | OCc1ccc(-c2ccc(-c3ccc(CO)s3)o2)s1 |
| InChI | InChI=1S/C14H12O3S2/c15-7-9-1-5-13(18-9)11-3-4-12(17-11)14-6-2-10(8-16)19-14/h1-6,15-16H,7-8H2 |
| InChI Key | KZENBFUSKMWCJF-UHFFFAOYSA-N |
| Transport Info | Product name: RITA (NSC 652287) |
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