| Chemical & Physical Properties | |
|---|---|
| CAS Number | 486424-20-8 |
| Catalog No. | 2A-1169180 |
| Chinese Name | 3-氨基-6-[4-(4-甲基哌嗪-1-基)磺酰基苯基]-n-吡啶-3-基吡嗪-2-羧酰胺 |
| Synonyms | 3-Amino-6-{4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl}-N-(3-pyridinyl)-2-pyrazinecarboxamide; AZD2858 |
| Molecular Formula | C21H23N7O3S |
| Molecular Weight | 453.517 |
| Density | 1.4±0.1 g/cm3 |
| Storage Condition | -20°C |
| Application | AZD2858 is a potent, orally available GSK-3 inhibitor that can inhibit the activities of GSK-3α and GSK-3β with IC50 values of 0.9 and 5 nM respectively, and can be used for the study of fracture he |
| PubChem ID | 15130219 |
| SMILES | CN1CCN(S(=O)(=O)c2ccc(-c3cnc(N)c(C(=O)Nc4cccnc4)n3)cc2)CC1 |
| InChI | InChI=1S/C21H23N7O3S/c1-27-9-11-28(12-10-27)32(30,31)17-6-4-15(5-7-17)18-14-24-20(22)19(26-18)21(29)25-16-3-2-8-23-13-16/h2-8,13-14H,9-12H2,1H3,(H2,22,24)(H,25,29) |
| InChI Key | FHCSBLWRGCOVPT-UHFFFAOYSA-N |
| Transport Info | Product name: AZD2858 |
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