![(3S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid monohydrochloride structure, CAS 177325-13-2](/structures/180000/169080_3_177325_13_2.png)
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 177325-13-2 |
| Catalog No. | 2A-1169001 |
| Chinese Name | 盐酸左氧氟沙星 |
| Synonyms | ac-7617; s454; Levofloxacin hydrochloride; EINECS 605-797-4 |
| Molecular Formula | C18H21ClFN3O4 |
| Molecular Weight | 397.828 |
| Boiling Point | 571.5ºC at 760 mmHg |
| Appearance | solid |
| Storage Condition | room temperature, dry |
| Application | Levofloxacin hydrochloride ((-)-ofloxacin) is an orally active antibiotic active against both Gram-positive and Gram-negative bacteria. Levofloxacin hydrochloride inhibits DNA gyrase and topoisomerase |
| HTC | 2934999090 |
| SMILES | CC1COc2c(N3CCN(C)CC3)c(F)cc3c(=O)c(C(=O)O)cn1c23.Cl |
| InChI Key | CAOOISJXWZMLBN-PPHPATTJSA-N |
| Use of | Levofloxacin ((-)-Ofloxacin) hydrochloride is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria. Levofloxacin hydrochloride inhibits the DNA gyrase and topoisomerase IV. Levofloxacin hydrochloride can be used for chronic periodontitis, airway inflammation and BK Viremia research[1][2][3][4]. Properties Name Levofloxacin hydrochloride Synonym More Synonyms Levofloxacin hydrochloride Biological Activity Description Levofloxacin ((-)-Ofloxacin) hydrochloride is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria. Levofloxacin hydrochloride inhibits the DNA gyrase and topoisomerase IV. Levofloxacin hydrochloride can be used for chronic periodontitis, airway inflammation and BK Viremia research[1][2][3][4]. Related Catalog Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis Signaling Pathways >> Anti-infection >> Bacterial References [1]. Siva, R., et al., Effect of levofloxacin on neutrophilic airway inflammation in stable COPD: a randomized, double-blind, placebo-controlled trial. Int J Chron Obstruct Pulmon Dis, 2014. 9: p. 179-86. [2]. Pradeep, A.R., et al., Clinical and microbiological effects of levofloxacin in the treatment of chronic periodontitis: a randomized, placebo-controlled clinical trial. J Investig Clin Dent, 2014. [3]. Lee, B.T., et al., Efficacy of Levofloxacin in the Treatment of BK Viremia: A Multicenter, Double-Blinded, Randomized, Placebo-Controlled Trial. Clin J Am Soc Nephrol, 2014. [4]. Drlica K, et al. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61(3):377-92. Chemical & Physical Properties Exact Mass 397.120453 PSA 75.01000 LogP 2.34890 InChIKey CAOOISJXWZMLBN-PPHPATTJSA-N Safety Information HS Code 2934999090 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| Related Products in Pharmaceutical Intermediates | ||
|---|---|---|
| 2-(2-ethoxyacetyl)-1,8-dimethylimidazo[1,2-a]quinoxalin-4(5H)-one | 164329-39-9 | 2A-1168922 |
| (2S,5R)-5-[(benzyloxy)amino]piperidine-2-carboxamide | 1416134-49-0 | 2A-1168930 |
| (2S,5R)-ethyl 5-(benzyloxyaMino)piperidine-2-carboxylate | 1416134-47-8 | 2A-1168931 |
| (S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethylaMine N-acetyl-L-leucine salt | 608141-43-1 | 2A-1168938 |
| 1-ethyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine | 1909308-00-4 | 2A-1168941 |
| (1R,4S)-CIS-4-ACETOXY-2-CYCLOPENTEN-1-OL | 60176-77-4 | 2A-1169006 |
| (2S,4S)-Argatroban | 189264-03-7 | 2A-1169008 |
| N-methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-7H-Pyrrolo[2,3-d]pyrimidin-4-amine hydrochloride | 1655430-59-3 | 2A-1169056 |
| (S)-Allyl 2-((((9H-fluoren-9-yl)Methoxy)carbonyl)aMino)-6-aMinohexanoate hydrochloride | 815619-80-8 | 2A-1169154 |
| Methyl 2-((4-bromophenyl)(tert-butoxycarbonyl)amino)acetate | 787576-32-3 | 2A-1169155 |
| Browse all Pharmaceutical Intermediates products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS