CAS Number77544-60-6
Synonymstoluene-4-sulfonic acid 2-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxy}-ethyl ester; tetraglycol-Ts; Ethanol,2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-,1-(4-Methylbenzenesulfonate); [2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethyl-4-methylbenzenesulfonate; Ts-tetraglycol; tetraethyleneglycol monotosylate
Molecular FormulaC15H24O7S
Molecular Weight348.41200
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 77544-60-6 |
| Catalog No. | 2A-1167358 |
| Chinese Name | 四乙二醇单对甲苯磺酸酯 |
| Synonyms | toluene-4-sulfonic acid 2-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethoxy}-ethyl ester; tetraglycol-Ts; Ethanol,2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]-,1-(4-Methylbenzenesulfonate); [2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethyl-4-methylbenzenesulfonate; Ts-tetraglycol; tetraethyleneglycol monotosylate |
| Molecular Formula | C15H24O7S |
| Molecular Weight | 348.41200 |
| Storage Condition | room temperature, dry |
| Application | Tetraethylene glycol monotosylate is a cleavable acylhydrazone-based ADC linker for the synthesis of antibody-drug conjugates (ADCs). |
| HTC | 2909499000 |
| PubChem ID | 54016181 |
| SMILES | Cc1ccc(S(=O)(=O)OCCOCCOCCOCCO)cc1 |
| InChI | InChI=1S/C15H24O7S/c1-14-2-4-15(5-3-14)23(17,18)22-13-12-21-11-10-20-9-8-19-7-6-16/h2-5,16H,6-13H2,1H3 |
| InChI Key | FGDJUEZBMFELRW-UHFFFAOYSA-N |
| Hazard Symbols | transportation |
| MSDS | msds/167384_2_77544_60_6.pdf |
| Bioactivity | Tetraethylene glycol monotosylate is a cleavable and acylhydrazone-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker Target Cleavable In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. References [1]. Park KD, et al. Useful tools for biomolecule isolation, detection, and identification: acylhydrazone-based cleavable linkers.Chem Biol. 2009 Jul 31;16(7):763-72. Chemical & Physical Properties Molecular Formula C15H24O7S Molecular Weight 348.41200 Exact Mass 348.12400 PSA 110.67000 LogP 1.21000 InChIKey FGDJUEZBMFELRW-UHFFFAOYSA-N SMILES Cc1ccc(S(=O)(=O)OCCOCCOCCOCCO)cc1 |
| Use of | Tetraethylene glycol monotosylate is a cleavable and acylhydrazone-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Properties Name 2-[2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol Synonym More Synonyms Tetraethylene glycol monotosylate Biological Activity Description Tetraethylene glycol monotosylate is a cleavable and acylhydrazone-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. References [1]. Park KD, et al. Useful tools for biomolecule isolation, detection, and identification: acylhydrazone-based cleavable linkers.Chem Biol. 2009 Jul 31;16(7):763-72. Chemical & Physical Properties Molecular Formula C15H24O7S Exact Mass 348.12400 PSA 110.67000 LogP 1.21000 InChIKey FGDJUEZBMFELRW-UHFFFAOYSA-N |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 5.5% Ordinary tariff: 30.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Dangerous Regulations for land transport: 2927 International Dangerous Regulations for sea transport: 2927 International Dangerous Regulations for air transport: 2927 14.2 United Nations shipping name European Land Transport Dangerous Regulations: TOXIC LIQUID, CORROSIVE, ORGANIC, N.O.S. (Tetraethylene glycol p-toluenesulfonate) IMDG: TOXIC LIQUID, CORROSIVE, ORGANIC, N.O.S. (Tetraethylene glycol p-toluenesulfonate) International air transport hazard regulations: Toxic liquid, corrosive, organic, n.o.s. (Tetraethylene glycol p-toluenesulfonate) 14.3 Transport hazard categories European land transport risk code: 6.1 (8) International sea transport risk code: 6.1 (8) International air transport risk code: 6.1 (8) 14.4 Package group European Dangerous Regulations for land transport: II International Dangerous Regulations for sea transport: II International Dangerous Regulations for air transport: II 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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