CAS Number60-01-5
SynonymsTributyrinine; MFCD00009392; 1,2,3-Propanetriyl tributanoate; Butanoic acid, 1,2,3-propanetriyl ester; Propane-1,2,3-triyl tributanoate; Tributyroin; glyceryl tributyrate; Tributin; Butyryl triglyceride; Glycerol tributyrate; 2,3-di(butanoyloxy)propyl butanoate; EINECS 200-451-5; glycerol tributanoate; 1,2,3-Tributyrylglycerol; Butanoic acid,1,2,3-propanetriyl ester; butyrin; TRIBUTYRIN
Molecular FormulaC15H26O6
Molecular Weight302.363
Density1.1±0.1 g/cm3
Boiling Point307.5±0.0 °C at 760 mmHg
Melting Point-75 °C
Appearancecolorless liquid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 60-01-5 |
| Catalog No. | 2A-1166843 |
| Chinese Name | 三丁酸甘油酯 |
| Synonyms | Tributyrinine; MFCD00009392; 1,2,3-Propanetriyl tributanoate; Butanoic acid, 1,2,3-propanetriyl ester; Propane-1,2,3-triyl tributanoate; Tributyroin; glyceryl tributyrate; Tributin; Butyryl triglyceride; Glycerol tributyrate; 2,3-di(butanoyloxy)propyl butanoate; EINECS 200-451-5; glycerol tributanoate; 1,2,3-Tributyrylglycerol; Butanoic acid,1,2,3-propanetriyl ester; butyrin; TRIBUTYRIN |
| Molecular Formula | C15H26O6 |
| Molecular Weight | 302.363 |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 307.5±0.0 °C at 760 mmHg |
| Melting Point | -75 °C |
| Appearance | colorless liquid |
| Storage Condition | This product should be sealed and stored in a cool |
| Application | Tributyrin (Glyceryl tributyrate) is a neutral short-chain fatty acid triglyceride that is a stable, rapidly absorbed butyric acid prodrug. Tributyrin (Glyceryl tributyrate) diffuses through the cell |
| HTC | 2915900090 |
| PubChem ID | 238859 |
| SMILES | CCCC(=O)OCC(COC(=O)CCC)OC(=O)CCC |
| InChI | InChI=1S/C15H26O6/c1-4-7-13(16)19-10-12(21-15(18)9-6-3)11-20-14(17)8-5-2/h12H,4-11H2,1-3H3 |
| InChI Key | UYXTWWCETRIEDR-UHFFFAOYSA-N |
| MSDS | msds/166853_2_60_01_5.pdf |
| Bioactivity | Tributyrin (Glyceryl tributyrate), a neutral short-chain fatty acid triglyceride, is a stable and rapidly absorbed prodrug of Butyric Acid. Tributyrin diffuses through biological membranes and is metabolized by intracellular lipases, releasing effective butyrate directly into the cell in vivo. Tributyrin has potent antiproliferative, proapoptotic and differentiation-inducing effects[1]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Metabolic Disease References [1]. T Gaschott, et al. Tributyrin, a stable and rapidly absorbed prodrug of butyric acid, enhances antiproliferative effects of dihydroxycholecalciferol in human colon cancer cells. J Nutr. 2001 Jun;131(6):1839-43. [2]. Claudia P Schröder, et al. Tributyrin-induced differentiation promotes apoptosis of LS 174T colon cancer cells in vitro. Int J Oncol. 2002 Jan;20(1):195-200. Chemical & Physical Properties Density 1.1±0.1 g/cm3 Boiling Point 307.5±0.0 °C at 760 mmHg Melting Point -75 °C Molecular Formula C15H26O6 Molecular Weight 302.363 Flash Point 173.9±0.0 °C Exact Mass 302.172943 PSA 78.90000 LogP 2.95 Vapour Pressure 0.0±0.6 mmHg at 25°C Index of Refraction 1.448 InChIKey UYXTWWCETRIEDR-UHFFFAOYSA-N SMILES CCCC(=O)OCC(COC(=O)CCC)OC(=O)CCC Storage condition Store at RT. Stability Stable. Incompatible with strong oxidizing agents. |
| Use of | Tributyrin (Glyceryl tributyrate), a neutral short-chain fatty acid triglyceride, is a stable and rapidly absorbed prodrug of Butyric Acid. Tributyrin diffuses through biological membranes and is metabolized by intracellular lipases, releasing effective butyrate directly into the cell in vivo. Tributyrin has potent antiproliferative, proapoptotic and differentiation-inducing effects[1]. Properties Articles66 Name tributyrin Synonym More Synonyms butyrin Biological Activity Description Tributyrin (Glyceryl tributyrate), a neutral short-chain fatty acid triglyceride, is a stable and rapidly absorbed prodrug of Butyric Acid. Tributyrin diffuses through biological membranes and is metabolized by intracellular lipases, releasing effective butyrate directly into the cell in vivo. Tributyrin has potent antiproliferative, proapoptotic and differentiation-inducing effects[1]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Metabolic Disease References [1]. T Gaschott, et al. Tributyrin, a stable and rapidly absorbed prodrug of butyric acid, enhances antiproliferative effects of dihydroxycholecalciferol in human colon cancer cells. J Nutr. 2001 Jun;131(6):1839-43. [2]. Claudia P Schröder, et al. Tributyrin-induced differentiation promotes apoptosis of LS 174T colon cancer cells in vitro. Int J Oncol. 2002 Jan;20(1):195-200. Chemical & Physical Properties Molecular Formula C15H26O6 Exact Mass 302.172943 PSA 78.90000 Index of Refraction 1.448 InChIKey UYXTWWCETRIEDR-UHFFFAOYSA-N SMILES CCCC(=O)OCC(COC(=O)CCC)OC(=O)CCC Storage condition Store at RT. Stability Stable. Incompatible with strong oxidizing agents. |
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