
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1025967-78-5 |
| Catalog No. | 2A-1166587 |
| Chinese Name | 立他司特 |
| Synonyms | Lifitegrast; SAR 1118 |
| Molecular Formula | C29H24Cl2N2O7S |
| Molecular Weight | 615.481 |
| Purity | 98.00 |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 811.9±65.0 °C at 760 mmHg |
| Appearance | powder |
| Storage Condition | -20℃ |
| Application | Lifitegrast is an antagonist of the integrin lymphocyte function-associated antigen-1 (LFA-1); the IC50 for inhibiting attachment of Jurkat T cells to ICAM-1 is 2.98nM. |
| SMILES | CS(=O)(=O)c1cccc(CC(NC(=O)c2c(Cl)cc3c(c2Cl)CCN(C(=O)c2ccc4ccoc4c2)C3)C(=O)O)c1 |
| InChI Key | JFOZKMSJYSPYLN-QHCPKHFHSA-N |
| Transport Info | Product name: Lifitegrast |
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