CAS Number186020-66-6
SynonymsHydroxy-PEG3-t-butyl ester; 12-hydroxy-4,7,10-trioxadodecanoic acid tert-butyl ester; tert-Butyl triethylene glycol-O-propionate; tert-Butyl 12-hydroxy-4,7,10-trioxadodecanoate
Molecular FormulaC13H26O6
Molecular Weight278.34
Purity≥97.0 (GC)%
Density1.057g/cm3
Boiling Point365.8ºC at 760 mmHg
Appearanceliquid
EINECS0
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 186020-66-6 |
| Catalog No. | 2A-0164973 |
| Chinese Name | 12-羟基-4,7,10-三氧杂十二酸叔丁酯 |
| Synonyms | Hydroxy-PEG3-t-butyl ester; 12-hydroxy-4,7,10-trioxadodecanoic acid tert-butyl ester; tert-Butyl triethylene glycol-O-propionate; tert-Butyl 12-hydroxy-4,7,10-trioxadodecanoate |
| Molecular Formula | C13H26O6 |
| Molecular Weight | 278.34 |
| Purity | ≥97.0 (GC) |
| Density | 1.057g/cm3 |
| Boiling Point | 365.8ºC at 760 mmHg |
| Appearance | liquid |
| Storage Condition | Room temperature, dry, sealed |
| Application | Hydroxy-PEG2-(CH2)2-Boc is an ADC linker used for the synthesis of antibody-drug conjugates (ADC). Hydroxy-PEG2-(CH2)2-Boc is derived from patent WO2004008101A2 (compound 196). |
| EINECS | 0 |
| HTC | 2918990090 |
| UN(IATA) | 0 |
| PubChem ID | 57652943 |
| MDL Number | MFCD03791106 |
| SMILES | CC(C)(C)OC(=O)CCOCCOCCOCCO |
| InChI | 1S/C13H26O6/c1-13(2,3)19-12(15)4-6-16-8-10-18-11-9-17-7-5-14/h14H,4-11H2,1-3H3 |
| InChI Key | KSXVEOLRERRELV-UHFFFAOYSA-N |
| Beilstein/REAXYS | 7638988 |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| Hazard Symbols | transportation |
| MSDS | msds/164973_1_186020_66_6.pdf |
| Bioactivity | Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196)[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker Target Non-cleavable In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. References [1]. Qingqi Chen,et al. The use of isocyanate linkers to make hydrolyzable active agent biopolymer conjugates. Patent WO2004008101A2. Chemical & Physical Properties Density 1.057g/cm3 Boiling Point 365.8ºC at 760 mmHg Molecular Formula C13H26O6 Molecular Weight 278.34200 Flash Point 125.2ºC Exact Mass 278.17300 PSA 74.22000 LogP 0.76030 Vapour Pressure 7.78E-07mmHg at 25°C Index of Refraction 1.45 InChIKey KSXVEOLRERRELV-UHFFFAOYSA-N SMILES CC(C)(C)OC(=O)CCOCCOCCOCCO |
| Use of | Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196)[1]. Properties Name tert-butyl 3-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]propanoate Synonym More Synonyms Hydroxy-PEG3-(CH2)2-Boc Biological Activity Description Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196)[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker Non-cleavable In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. References [1]. Qingqi Chen,et al. The use of isocyanate linkers to make hydrolyzable active agent biopolymer conjugates. Patent WO2004008101A2. Chemical & Physical Properties Molecular Formula C13H26O6 Exact Mass 278.17300 PSA 74.22000 LogP 0.76030 Index of Refraction 1.45 InChIKey KSXVEOLRERRELV-UHFFFAOYSA-N SMILES CC(C)(C)OC(=O)CCOCCOCCOCCO |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: No dangerous goods IMDG Code: No dangerous goods International Air Transport Dangerous Regulations: No dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special precautions for users No data available The company is not responsible for any damage caused by any operation or contact with the above products. For more terms of use, see invoice or package The reverse side of the mounting strip. |
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