CAS Number142356-33-0
Synonymstert-butyl N-(6-bromohexyl)carbamate; 2-Methyl-2-propanyl (6-bromohexyl)carbamate; tert-Butyl (6-bromohexyl)carbamate; Carbamic acid, N-(6-bromohexyl)-, 1,1-dimethylethyl ester
Molecular FormulaC11H22BrNO2
Molecular Weight280.20
Purity≥97.0 (GC)%
Density1.2±0.1 g/cm3
Boiling Point340.1±25.0 °C at 760 mmHg
Appearanceliquid
EINECS0
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 142356-33-0 |
| Catalog No. | 2A-1164617 |
| Chinese Name | 6-(Boc-氨基)溴己烷 |
| Synonyms | tert-butyl N-(6-bromohexyl)carbamate; 2-Methyl-2-propanyl (6-bromohexyl)carbamate; tert-Butyl (6-bromohexyl)carbamate; Carbamic acid, N-(6-bromohexyl)-, 1,1-dimethylethyl ester |
| Molecular Formula | C11H22BrNO2 |
| Molecular Weight | 280.20 |
| Purity | ≥97.0 (GC) |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 340.1±25.0 °C at 760 mmHg |
| Appearance | liquid |
| Storage Condition | 2-8°C |
| Application | Boc-NH-C6-Br is a cleavable bridge used in antibody drug conjugates (ADCs). |
| EINECS | 0 |
| HTC | 2924199090 |
| UN(IATA) | 0 |
| PubChem ID | 57653330 |
| MDL Number | MFCD06201019 |
| SMILES | O=C(NCCCCCCBr)OC(C)(C)C |
| InChI | 1S/C11H22BrNO2/c1-11(2,3)15-10(14)13-9-7-5-4-6-8-12/h4-9H2,1-3H3,(H,13,14) |
| InChI Key | NXQXVXILNVTMNA-UHFFFAOYSA-N |
| NACRES Code | NA.22 |
| UNSPSC | 12352200 |
| MSDS | msds/164617_1_142356_33_0.pdf |
| Use of | Boc-NH-C6-Br is a cleavable linker used for antibody-drug conjugates (ADC)[1]. Properties Name tert-Butyl (6-bromohexyl)carbamate Synonym More Synonyms tert-Butyl (6-bromohexyl)carbamate Biological Activity Description Boc-NH-C6-Br is a cleavable linker used for antibody-drug conjugates (ADC)[1]. Related Catalog Research Areas >> Cancer References [1]. Jan Anderl, et al. Amatoxin-antibody conjugates. WO2016142049A1. Chemical & Physical Properties Molecular Formula C11H22BrNO2 Exact Mass 279.083374 PSA 38.33000 Index of Refraction 1.473 InChIKey NXQXVXILNVTMNA-UHFFFAOYSA-N SMILES CC(C)(C)OC(=O)NCCCCCCBr Safety Information Signal Word Danger Hazard Statements H318 Precautionary Statements P280-P305 + P351 + P338 Personal Protective Equipment Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter Hazard Codes Xi Risk Phrases R41 Safety Phrases 26-39 WGK Germany 3 HS Code 2924199090 Synthetic Route Tert-Butyl N-(6... CAS#:75937-12-1 tert-Butyl (6-b... CAS#:142356-33-0 Literature: Keller; Haner Helvetica Chimica Acta, 1993 , vol. 76, # 2 p. 884 - 892 Tert-Butyl N-(6... CAS#:75937-12-1 Triphenylphosphine CAS#:603-35-0 tert-Butyl (6-b... CAS#:142356-33-0 Literature: US6878715 B1, ; 6-Aminohexan-1-ol CAS#:4048-33-3 Di-tert-butyl d... CAS#:24424-99-5 Tert-Butyl N-(6... CAS#:75937-12-1 Triphenylphosphine CAS#:603-35-0 Precursor & DownStream Precursor 9 CAS#:75937-12-1 Tert-Butyl N-(6... CAS#:603-35-0 Triphenylphosphine CAS#:4048-33-3 6-Aminohexan-1-ol CAS#:24424-99-5 Di-tert-butyl d... DownStream 1 CAS#:1938-58-5 N1,N1-Dimethylh... |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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