CAS Number828934-41-4
SynonymsSodium (2R)-2-[6-(4-chlorophenoxy)hexyl]-2-oxiranecarboxylate; 2-Oxiranecarboxylic acid, 2-[6-(4-chlorophenoxy)hexyl]-, sodium salt, (2R)- (1:1); cc-140; (+)-Etomoxir (sodium salt); ANTI-EAPII(TTRAP); (2R)-2-[6-(4-Chlorophenoxy)hexyl]oxiranecarboxylic acid sodium salt; MFCD07787411; (+)-Etomoxir sodium salt; (R)-(+)-Etomoxir (sodium salt)
Molecular FormulaC15H18ClNaO4
Molecular Weight320.74
Purity≥98 (HPLC)%
Appearancesolid
EINECS0
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 828934-41-4 |
| Catalog No. | 2A-0164109 |
| Chinese Name | (2R)-2-[6-(4-氯苯氧基)己基]环氧乙烷甲酸钠 |
| Synonyms | Sodium (2R)-2-[6-(4-chlorophenoxy)hexyl]-2-oxiranecarboxylate; 2-Oxiranecarboxylic acid, 2-[6-(4-chlorophenoxy)hexyl]-, sodium salt, (2R)- (1:1); cc-140; (+)-Etomoxir (sodium salt); ANTI-EAPII(TTRAP); (2R)-2-[6-(4-Chlorophenoxy)hexyl]oxiranecarboxylic acid sodium salt; MFCD07787411; (+)-Etomoxir sodium salt; (R)-(+)-Etomoxir (sodium salt) |
| Molecular Formula | C15H18ClNaO4 |
| Molecular Weight | 320.74 |
| Purity | ≥98 (HPLC) |
| Appearance | solid |
| Storage Condition | -20℃ |
| Application | (R)-Etomoxir sodium salt is the R-isomer of Etomoxir sodium salt. It is an inhibitor of carnitine palmitoyltransferase I (CPT-I) and can inhibit the oxidation of palmitate in humans, rats and guinea p |
| EINECS | 0 |
| HTC | 0 |
| UN(IATA) | 0 |
| PubChem ID | 85740217 |
| MDL Number | MFCD07787411 |
| SMILES | [Na+].Clc1ccc(cc1)OCCCCCC[C@]2(OC2)C(=O)[O-] |
| InChI | 1S/C15H19ClO4.Na/c16-12-5-7-13(8-6-12)19-10-4-2-1-3-9-15(11-20-15)14(17)18;/h5-8H,1-4,9-11H2,(H,17,18);/q;+1/p-1/t15-;/m1./s1 |
| InChI Key | RPACBEVZENYWOL-XFULWGLBSA-M |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| Hazard Symbols | transportation |
| MSDS | msds/164109_1_828934_41_4.pdf |
| Bioactivity | (R)-Etomoxir sodium salt is the R-form of Etomoxir sodium salt, acts as an inhibitorof carnitine palmitoyltransferase I (CPT-I), and inhibits palmitate β-oxidation in human, rat and guinea pig. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease Target CPT-1[1] In Vitro (R)-Etomoxir sodium salt is the R-form of Etomoxir sodium salt, acts as an inhibitorof carnitine palmitoyltransferase I (CPT-I), and inhibits palmitate β-oxidation in human, rat and guinea pig[1]. References [1]. Agius L, et al. Differences between human, rat and guinea pig hepatocyte cultures. A comparative study of their rates of beta-oxidation and esterification of palmitate and their sensitivity to R-etomoxir. Biochem Pharmacol. 1991 Oct 9;42(9):1711-5. Chemical & Physical Properties Molecular Formula C15H18ClNaO4 Molecular Weight 320.744 Exact Mass 320.079132 PSA 61.89000 LogP 2.18820 InChIKey RPACBEVZENYWOL-XFULWGLBSA-M SMILES O=C([O-])C1(CCCCCCOc2ccc(Cl)cc2)CO1.[Na+] Storage condition -20℃ |
| Use of | (R)-Etomoxir sodium salt is the R-form of Etomoxir sodium salt, acts as an inhibitorof carnitine palmitoyltransferase I (CPT-I), and inhibits palmitate β-oxidation in human, rat and guinea pig. Properties Name sodium,(2R)-2-[6-(4-chlorophenoxy)hexyl]oxirane-2-carboxylate Synonym More Synonyms Etomoxir (Na salt) Biological Activity Description (R)-Etomoxir sodium salt is the R-form of Etomoxir sodium salt, acts as an inhibitorof carnitine palmitoyltransferase I (CPT-I), and inhibits palmitate β-oxidation in human, rat and guinea pig. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease In Vitro (R)-Etomoxir sodium salt is the R-form of Etomoxir sodium salt, acts as an inhibitorof carnitine palmitoyltransferase I (CPT-I), and inhibits palmitate β-oxidation in human, rat and guinea pig[1]. References [1]. Agius L, et al. Differences between human, rat and guinea pig hepatocyte cultures. A comparative study of their rates of beta-oxidation and esterification of palmitate and their sensitivity to R-etomoxir. Biochem Pharmacol. 1991 Oct 9;42(9):1711-5. Chemical & Physical Properties Exact Mass 320.079132 PSA 61.89000 LogP 2.18820 InChIKey RPACBEVZENYWOL-XFULWGLBSA-M Storage condition -20℃ |
| Transport Info | Product name: Purity: 99.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Dangerous Regulations for land transport: 2811 International Dangerous Regulations for sea transport: 2811 International Dangerous Regulations for air transport: 2811 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: TOXIC SOLID, ORGANIC, N.O.S. ((+)-Etomoxir sodium) IMDG: TOXIC SOLID, ORGANIC, N.O.S. ((+)-Etomoxir sodium) International air transport hazard regulations: Toxic solid, organic, n.o.s. ((+)-Etomoxir sodium) 14.3 Transport hazard categories European Land Transport Danger Regulations: 6.1 International Maritime Transport Danger Regulations: 6.1 International Air Transport Danger Regulations: 6.1 14.4 Package group European Land Transport Danger Regulations: III International Maritime Transport Danger Regulations: III International Air Transport Danger Regulations: III 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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