![N-METHYL-N-(3-(3-METHYL-[1,2,4]TRIAZOLO[4,3-B]PYRIDAZIN-6-YL)PHENYL)ACETAMIDE structure, CAS 108825-65-6](/structures/180000/162735_1_108825_65_6.png)
CAS Number108825-65-6
SynonymsAcetamide,N-methyl-N-[3-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)phenyl]; N-Methyl-N-(3-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)acetamide
Molecular FormulaC15H15N5O
Molecular Weight281.31
Purity≥98 (HPLC)%
Density1.28g/cm3
Melting Point200ºC
Appearancepowder
EINECS0
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 108825-65-6 |
| Catalog No. | 2A-0162735 |
| Chinese Name | N-甲基-n-(3-(3-甲基-[1,2,4]噻唑并[4,3-b]吡嗪-6-基)苯基)乙酰胺 |
| Synonyms | Acetamide,N-methyl-N-[3-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)phenyl]; N-Methyl-N-(3-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)acetamide |
| Molecular Formula | C15H15N5O |
| Molecular Weight | 281.31 |
| Purity | ≥98 (HPLC) |
| Density | 1.28g/cm3 |
| Melting Point | 200ºC |
| Appearance | powder |
| Storage Condition | -20°C |
| Application | Lin28-let-7 antagonist 1 (compound 1632) is a potent antagonist of the Lin28/pre-let-7 interaction. Lin28-let-7 antagonist 1 inhibits the binding of Lin28A to prolet-7a-2 with an IC50 of 8μM. Lin28-le |
| EINECS | 0 |
| HTC | 2933990090 |
| UN(IATA) | 0 |
| PubChem ID | 3160966 |
| MDL Number | MFCD01567008 |
| SMILES | [n]21nc(ccc2nnc1C)c3cc(ccc3)N(C)C(=O)C |
| InChI | 1S/C15H15N5O/c1-10-16-17-15-8-7-14(18-20(10)15)12-5-4-6-13(9-12)19(3)11(2)21/h4-9H,1-3H3 |
| InChI Key | WPAQLESUVYGUJZ-UHFFFAOYSA-N |
| NACRES Code | NA.28 |
| UNSPSC | 12352200 |
| MSDS | msds/162735_1_108825_65_6.pdf |
| Use of | Properties Name N-methyl-N-[3-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]acetamide Synonym More Synonyms Lin28-IN-1632 Biological Activity Related Catalog Research Areas >> Cancer Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease References [1]. Roos M, et al. A Small-Molecule Inhibitor of Lin28. ACS Chem Biol. 2016 Oct 21;11(10):2773-2781. Chemical & Physical Properties Molecular Formula C15H15N5O Exact Mass 281.12800 PSA 63.39000 LogP 2.08240 Index of Refraction 1.665 InChIKey WPAQLESUVYGUJZ-UHFFFAOYSA-N Safety Information Hazard Codes Xi: Irritant; HS Code 2933990090 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| Related Products in Pharmaceutical Intermediates | ||
|---|---|---|
| N-CYCLOHEXYL-2-(4-METHOXYPHENYL)IMIDAZO[1,2-A]PYRAZIN-3-AMINE | 879592-32-2 | 2A-0162267 |
| N-ETHYL-2-(4-PIPERIDINYLOXY)ACETAMIDE | 521074-81-7 | 2A-0162348 |
| N-METHYL-2-(3-NITROPHENYL)-N-((1S,2S)-2-(PYRROLIDIN-1-YL)-2,3-DIHYDRO-1H-INDEN-1-YL)ACETAMIDE | 130610-93-4 | 2A-0162624 |
| N-METHYL-3-(3-METHYL-[1,2,4]TRIAZOLO[4,3-B]PYRIDAZIN-6-YL)ANILINE | 108810-87-3 | 2A-0162659 |
| N-METHYL-4-CHLORO-7-AZAINDOLE | 74420-05-6 | 2A-0162687 |
| N-METHYLIMIDAZO[1,2-A]PYRIDIN-2-AMINE DIHYDROCHLORIDE | 165736-20-9 | 2A-0162777 |
| N-TOSYL-4-CHLORO-7-AZAINDOLE | 348640-05-1 | 2A-1162863 |
| N1,N3-BIS((R)-2-HYDROXY-1-PHENYLETHYL)-2,2-DIMETHYLMALONAMIDE | 178958-49-1 | 2A-0162942 |
| OXAZOLO[4,5-B]PYRIDINE | 273-97-2 | 2A-0163345 |
| OXAZOLO[4,5-B]PYRIDINE-2-THIOL | 211949-57-4 | 2A-0163346 |
| Browse all Pharmaceutical Intermediates products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS