CAS Number827031-83-4
SynonymsVerubulin; N-(4-Methoxyphenyl)-N,2-dimethyl-4-quinazolinamine; N-(4-methoxyphenyl)-N,2-dimethylquinazolin-4-amine
Molecular FormulaC17H17O1N3
Molecular Weight279.34
Purity96+%
Density1.2±0.1 g/cm3
Boiling Point398.7±38.0 °C at 760 mmHg
Melting Point86-90 °C
EINECS0
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 827031-83-4 |
| Catalog No. | 2A-0161326 |
| Chinese Name | (4-甲氧基苯基)(甲基)(2-甲基喹唑啉-4-基)胺 |
| Synonyms | Verubulin; N-(4-Methoxyphenyl)-N,2-dimethyl-4-quinazolinamine; N-(4-methoxyphenyl)-N,2-dimethylquinazolin-4-amine |
| Molecular Formula | C17H17O1N3 |
| Molecular Weight | 279.34 |
| Purity | 96+ |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 398.7±38.0 °C at 760 mmHg |
| Melting Point | 86-90 °C |
| Storage Condition | -20°C |
| Application | Verubulin (MPC-6827) is a highly efficient and broad-spectrum microtubule blocker with cytotoxic activity in vitro and in vivo and has the potential to become an ideal drug for the treatment of variou |
| EINECS | 0 |
| HTC | 2933990090 |
| UN(IATA) | 0 |
| PubChem ID | 16511070 |
| MDL Number | MFCD16495771 |
| SMILES | COc1ccc(N(C)c2nc(C)nc3ccccc23)cc1 |
| InChI | InChI=1S/C17H17N3O/c1-12-18-16-7-5-4-6-15(16)17(19-12)20(2)13-8-10-14(21-3)11-9-13/h4-11H,1-3H3 |
| InChI Key | SNHCRNMVYDHVDT-UHFFFAOYSA-N |
| MSDS | msds/161326_1_827031_83_4.pdf |
| Use of | Verubulin (MPC-6827) is a microtubule-disrupting agent with potent and broad-spectrum in vitro and in vivo cytotoxic activities, and acts as a promising candidate for the treatment of multiple cancer types[1]. Properties Name N-(4-Methoxyphenyl)-N,2-dimethylquinazolin-4-amine Synonym More Synonyms Verubulin Biological Activity Description Verubulin (MPC-6827) is a microtubule-disrupting agent with potent and broad-spectrum in vitro and in vivo cytotoxic activities, and acts as a promising candidate for the treatment of multiple cancer types[1]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin Microtubule[1] References [1]. Kasibhatla S, et al. MPC-6827: a small-molecule inhibitor of microtubule formation that is not a substrate for multidrug resistance pumps. Cancer Res. 2007 Jun 15;67(12):5865-71. Chemical & Physical Properties Molecular Formula C17H17N3O Exact Mass 279.137177 PSA 38.25000 Index of Refraction 1.652 InChIKey SNHCRNMVYDHVDT-UHFFFAOYSA-N Safety Information HS Code 2933990090 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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