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Home > Products > Pharmaceutical R&D Materials > Heterocyclic Building Blocks > N-(2,3-DIMETHYL-5,6,7,8-TETRAHYDROFURO[2,3-B]QUINOLIN-4-YL)-2-(2-OXOPYRROLIDIN-1-YL)ACETAMIDE
N-(2,3-DIMETHYL-5,6,7,8-TETRAHYDROFURO[2,3-B]QUINOLIN-4-YL)-2-(2-OXOPYRROLIDIN-1-YL)ACETAMIDE structure, CAS 135463-81-9

N-(2,3-DIMETHYL-5,6,7,8-TETRAHYDROFURO[2,3-B]QUINOLIN-4-YL)-2-(2-OXOPYRROLIDIN-1-YL)ACETAMIDE

CAS Number135463-81-9

SynonymsN-(2,3-Dimethyl-5,6,7,8-tetrahydrofuro(2,3-b)quinolin-4-yl)-2-(2-oxopyrrolidin-1-yl)acetamide; N-(2,3-Dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2-oxo-1-pyrrolidinyl)acetamide; Coluracetam [INN]; coluracetam; N-(2,3-dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2-oxopyrrolidin-1-yl)acetamide; UNII-V6FL6O5GR7

Molecular FormulaC19H23N3O3

Molecular Weight341.40

Purity96+%

Density1.3±0.1 g/cm3

Boiling Point634.1±55.0 °C at 760 mmHg

Melting Point225 °C

Flash Point

Appearancesolid

EINECS0

MSDSChineseEnglish

Symbol

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Cat. No.: 2A-0160474 Purity: 96+%
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Quality Control of [ 135463-81-9 ] Purity: 96+% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number135463-81-9
Catalog No.2A-0160474
Chinese Name考拉西坦
SynonymsN-(2,3-Dimethyl-5,6,7,8-tetrahydrofuro(2,3-b)quinolin-4-yl)-2-(2-oxopyrrolidin-1-yl)acetamide; N-(2,3-Dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2-oxo-1-pyrrolidinyl)acetamide; Coluracetam [INN]; coluracetam; N-(2,3-dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2-oxopyrrolidin-1-yl)acetamide; UNII-V6FL6O5GR7
Molecular FormulaC19H23N3O3
Molecular Weight341.40
Purity96+
Density1.3±0.1 g/cm3
Boiling Point634.1±55.0 °C at 760 mmHg
Melting Point225 °C
Appearancesolid
Storage ConditionStore under inert gas; avoid air
ApplicationColuracetam (MKC-231) is a new choline absorption enhancer.
EINECS0
HTC2942000000
UN(IATA)0
PubChem ID329794876
MDL NumberMFCD00901416
SMILESCC(C1=C(O2)N=C3C(CCCC3)=C1NC(CN(CCC4)C4=O)=O)=C2C
InChI1S/C19H23N3O3/c1-11-12(2)25-19-17(11)18(13-6-3-4-7-14(13)20-19)21-15(23)10-22-9-5-8-16(22)24/h3-10H2,1-2H3,(H,20,21,23)
InChI KeyPSPGQHXMUKWNDI-UHFFFAOYSA-N
NACRES CodeNA.21
UNSPSC12352200
MSDSmsds/160474_1_135463_81_9.pdf
Use ofProperties Name N-(2,3-dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2-oxopyrrolidin-1-yl)acetamide Synonym More Synonyms coluracetam Biological Activity Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease References [1]. Bessho T, et al. Effect of the novel high affinity choline uptake enhancer 2-(2-oxopyrrolidin-1-yl)-N-(2,3-dimethyl-5,6,7,8-tetrahydrofuro[2,3-b] quinolin-4-yl)acetoamide on deficits of water maze learning in rats. Arzneimittelforschung. 1996 Apr;46(4):369-73. [2]. Murai S, et al. MKC-231, a choline uptake enhancer, ameliorates working memory deficits and decreased hippocampal acetylcholine induced by ethylcholine aziridinium ion in mice. J Neural Transm Gen Sect. 1994;98(1):1-13. Chemical & Physical Properties Molecular Formula C19H23N3O3 Exact Mass 341.173950 PSA 75.44000 Index of Refraction 1.641 InChIKey PSPGQHXMUKWNDI-UHFFFAOYSA-N Safety Information Hazard Codes Xi HS Code 2942000000
Tax Rebate13.0%
SupervisionNone. MFN tariff: 6.5%. Ordinary tariff: 20.0%
Transport InfoProduct name: Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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