CAS Number108-30-5
SynonymsSAN; 3,4-dihydrofuran-2,5-dione; succinylanhydride; Dihydrofuran-2,5-dione; dihydro-furan-2.5-dione; succinic acid anhydride; tetrahydrofuran-2,5-dione; Oxolan-2,5-dione; SAA; Succinic Anhydride; SUCCINYL OXIDE; 2,5-Diketotetrahydrofuran; dihydrothran-2,5-dione; MFCD00005525; dihydro-2,5-furandione; EINECS 203-570-0
Molecular FormulaC4H4O3
Molecular Weight100.07
Purity≥99 (GC)%
Density1.4±0.1 g/cm3
Boiling Point261 °C (lit.)
Melting Point118-120 °C (lit.)
Appearancesolid
EINECS203-570-0
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 108-30-5 |
| Catalog No. | 2A-9015812 |
| Chinese Name | 丁二酸酐 |
| Synonyms | SAN; 3,4-dihydrofuran-2,5-dione; succinylanhydride; Dihydrofuran-2,5-dione; dihydro-furan-2.5-dione; succinic acid anhydride; tetrahydrofuran-2,5-dione; Oxolan-2,5-dione; SAA; Succinic Anhydride; SUCCINYL OXIDE; 2,5-Diketotetrahydrofuran; dihydrothran-2,5-dione; MFCD00005525; dihydro-2,5-furandione; EINECS 203-570-0 |
| Molecular Formula | C4H4O3 |
| Molecular Weight | 100.07 |
| Purity | ≥99 (GC) |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 261 °C (lit.) |
| Melting Point | 118-120 °C (lit.) |
| Appearance | solid |
| Water Solubility | <0.1 g/100 mL at 21 ºC (decomposes) |
| Storage Condition | 1.阴凉通风处密封存放。 2.用内衬塑料袋，外套编织袋包装。 Net weight 25kg. St |
| Application | Succinic anhydride is a cyclic anhydride and ADC linker. For detailed information, please refer to patent WO2009064913A1. Succinic anhydride reacts with the patented compound 4 to link the prodrug to |
| EINECS | 203-570-0 |
| HTC | 2932999099 |
| PubChem ID | 24854387 |
| MDL Number | MFCD00005525 |
| SMILES | O=C1CCC(=O)O1 |
| InChI | 1S/C4H4O3/c5-3-1-2-4(6)7-3/h1-2H2 |
| InChI Key | RINCXYDBBGOEEQ-UHFFFAOYSA-N |
| Beilstein/REAXYS | 108441 |
| NACRES Code | NA.23 |
| UNSPSC | 12162002 |
| Hazard Symbols | Transport |
| MSDS | msds/15812_1_108_30_5.pdf |
| Bioactivity | Succinic anhydride is a cyclic anhydride and an ADC linker extracted from patent WO2009064913A1. It can react with compound 4 of the patent to link the prodrug to an amine or hydroxy 1 group of a targeting polypeptide[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker Target Alkyl/ether References [1]. Dale Boger.et al. Chimer containing a targeting portion linked to a scission-activated duocarmycin-type prodrug. WO2009064913A1. Chemical & Physical Properties Density 1.4±0.1 g/cm3 Boiling Point 261.0±0.0 °C at 760 mmHg Melting Point 118-120 °C(lit.) Molecular Formula C4H4O3 Molecular Weight 100.073 Flash Point 122.1±15.9 °C Exact Mass 100.016045 PSA 43.37000 LogP -1.30 Vapour density 3.5 (vs air) Vapour Pressure 0.0±0.5 mmHg at 25°C Index of Refraction 1.470 InChIKey RINCXYDBBGOEEQ-UHFFFAOYSA-N SMILES O=C1CCC(=O)O1 Storage condition Store at 0-5°C Stability Stable. Incompatible with oxidising agents, strong acids, strong bases, alcohols, amines. Avoid exposure to water or moisture. Water Solubility <0.1 g/100 mL at 21 ºC (decomposes) |
| Use of | Properties Articles98 Name succinic anhydride Synonym More Synonyms Succinic anhydride Biological Activity Related Catalog Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker Alkyl/ether References [1]. Dale Boger.et al. Chimer containing a targeting portion linked to a scission-activated duocarmycin-type prodrug. WO2009064913A1. Chemical & Physical Properties Molecular Formula C4H4O3 Exact Mass 100.016045 PSA 43.37000 LogP -1.30 Vapour density 3.5 (vs air) Index of Refraction 1.470 InChIKey RINCXYDBBGOEEQ-UHFFFAOYSA-N Stability Stable. Incompatible with oxidising agents, strong acids, strong bases, alcohols, amines. Avoid exposure to water or moisture. |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 30.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 United Nations number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special precautions No data available |
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