
CAS Number12141-67-2
SynonymsSODIUM POLYTUNGSTATE; POM 1; 4-Acetyl-1,1-dimethylpiperazinium iodide; Sodium metatungstate monohydrate; EINECS 412-770-9; Sodium metatungstate; SODIUM POLYTINGSTATE; hexasodium tungstate hydrate; Sodium polytungstate solution; TUNGSTATEHEXASODIUM; MFCD00061466
Molecular Formula3Na2WO4 · 9WO3 · H2O
Molecular Weight2986.01
Purity≥85 WO<SUB>3</SUB> basis%
Density3.1 g/cm3
Appearancepowder or crystals
EINECS412-770-9
Symbol
Signal WordWarning
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| Chemical & Physical Properties | |
|---|---|
| CAS Number | 12141-67-2 |
| Catalog No. | 2A-9015702 |
| Chinese Name | 聚钨酸钠 |
| Synonyms | SODIUM POLYTUNGSTATE; POM 1; 4-Acetyl-1,1-dimethylpiperazinium iodide; Sodium metatungstate monohydrate; EINECS 412-770-9; Sodium metatungstate; SODIUM POLYTINGSTATE; hexasodium tungstate hydrate; Sodium polytungstate solution; TUNGSTATEHEXASODIUM; MFCD00061466 |
| Molecular Formula | 3Na2WO4 · 9WO3 · H2O |
| Molecular Weight | 2986.01 |
| Purity | ≥85 WO<SUB>3</SUB> basis |
| Density | 3.1 g/cm3 |
| Appearance | powder or crystals |
| Water Solubility | Soluble in water. |
| Storage Condition | Sealed and protected from light at room temperatur |
| Application | POM1 is a potent inhibitor of ectonucleoside triphosphate diphosphate hydrolase (NTPDase), with Ki values of 2.58 μM, 3.26 μM, and 28.8 μM for NTPDase 1, NTPDase 3, and NTPDase 2, respectively. POM1 |
| EINECS | 412-770-9 |
| PubChem ID | 329763629 |
| MDL Number | MFCD00061466 |
| SMILES | [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].O=[W](=O)=O.O=[W](=O)=O.O=[W](=O)=O.O=[W](=O)=O.O=[W](=O)=O.O=[W](=O)=O.O=[W](=O)=O.O=[W](=O)=O.O=[W](=O)=O.[O-][W]([O-])(=O)=O.[O-][W]([O-])(=O)=O.[O-][W]([O-])(=O)=O |
| InChI | 1S/6Na.39O.12W/q6*+1;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;6*-1;;;;;;;;;;;; |
| InChI Key | AZCSOJKJFMWYCX-UHFFFAOYSA-N |
| NACRES Code | NA.75 |
| UNSPSC | 12352207 |
| Hazard Symbols | Transport |
| MSDS | msds/15702_1_12141_67_2.pdf |
| Bioactivity | POM1 is a potent ecto-nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitor, with Ki values of 2.58 μM, 3.26 μM, and 28.8 μM for NTPDase 1, NTPDase 3 and NTPDase 2 respectively[1]. POM1 inhibits ATP breakdown but also blocks central synaptic transmission, an action independent of NTPDase inhibition[2]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease Target Ki: 2.58 μM (NTPDase 1), 3.26 μM (NTPDase 3), 28.8 μM (NTPDase 2)[1]. References [1]. Müller CE, et al. Polyoxometalates--a new class of potent ecto-nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitors. Bioorg Med Chem Lett. 2006 Dec 1;16(23):5943-7. [2]. Wall et al. The novel NTPDase inhibitor sodium polyoxotungstate (POM-1) inhibits ATP breakdown but also blocks central synaptic transmission, an action independent of NTPDase inhibition. Neuropharmacology. 2008 Dec;55(7):1251-8. Chemical & Physical Properties Density 3.1 g/cm3 Molecular Formula H2Na6O40W12 Molecular Weight 2986.01 Exact Mass 2969.15000 PSA 701.67000 Index of Refraction n20/D 1.5555 Storage condition Store at RT Water Solubility Soluble in water. |
| Use of | POM1 is a potent ecto-nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitor, with Ki values of 2.58 μM, 3.26 μM, and 28.8 μM for NTPDase 1, NTPDase 3 and NTPDase 2 respectively[1]. POM1 inhibits ATP breakdown but also blocks central synaptic transmission, an action independent of NTPDase inhibition[2]. Properties Name sodium metatungstate Synonym More Synonyms POM 1 Biological Activity Description POM1 is a potent ecto-nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitor, with Ki values of 2.58 μM, 3.26 μM, and 28.8 μM for NTPDase 1, NTPDase 3 and NTPDase 2 respectively[1]. POM1 inhibits ATP breakdown but also blocks central synaptic transmission, an action independent of NTPDase inhibition[2]. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease Ki: 2.58 μM (NTPDase 1), 3.26 μM (NTPDase 3), 28.8 μM (NTPDase 2)[1]. References [1]. Müller CE, et al. Polyoxometalates--a new class of potent ecto-nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitors. Bioorg Med Chem Lett. 2006 Dec 1;16(23):5943-7. [2]. Wall et al. The novel NTPDase inhibitor sodium polyoxotungstate (POM-1) inhibits ATP breakdown but also blocks central synaptic transmission, an action independent of NTPDase inhibition. Neuropharmacology. 2008 Dec;55(7):1251-8. Chemical & Physical Properties Molecular Formula H2Na6O40W12 Exact Mass 2969.15000 PSA 701.67000 Storage condition Store at RT Water Solubility Soluble in water. |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 United Nations number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special precautions No data available See reverse side of invoice or packing slip. |
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