CAS Number68-12-2
SynonymsN,N-dimethyl-malonamic acid ethyl ester; N,N-DIMETHYLFORMAMIDE; N,N-dimethyl-formamide; Dimethylformamide; MFCD00003284; dimetylformamide; DIMETHYL FORMAMIDE; EINECS 200-679-5; ethyl a-dimethylcarbamoylacetate; Dimethylcarbamoylessigsaeure-ethylester; ethyl N,N-dimethylamidomalonate; N,N-Dimethylformamid; DMF
Molecular FormulaHCON(CH3)2
Molecular Weight73.09
Purity≥99.8%
Density0.948 g/mL at 20 °C
Boiling Point153 °C (lit.)
Melting Point−61 °C (lit.)
Appearanceliquid
EINECS200-679-5
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 68-12-2 |
| Catalog No. | 2A-0201409 |
| Chinese Name | N,N-二甲基甲酰胺 |
| Synonyms | N,N-dimethyl-malonamic acid ethyl ester; N,N-DIMETHYLFORMAMIDE; N,N-dimethyl-formamide; Dimethylformamide; MFCD00003284; dimetylformamide; DIMETHYL FORMAMIDE; EINECS 200-679-5; ethyl a-dimethylcarbamoylacetate; Dimethylcarbamoylessigsaeure-ethylester; ethyl N,N-dimethylamidomalonate; N,N-Dimethylformamid; DMF |
| Molecular Formula | HCON(CH3)2 |
| Molecular Weight | 73.09 |
| Purity | ≥99.8 |
| Density | 0.948 g/mL at 20 °C |
| Boiling Point | 153 °C (lit.) |
| Melting Point | −61 °C (lit.) |
| Appearance | liquid |
| Water Solubility | soluble |
| Storage Condition | Storage precautions: Store in a cool, ventilated w |
| Packaging | III |
| Application | N, N-dimethylformamide (DMF) is widely used as a pharmaceutical solvent. N, N-dimethylformamide is a dipolar prosolvent with physical and chemical properties, so it is suitable as a solvent for capill |
| EINECS | 200-679-5 |
| HTC | 2924191000 |
| PubChem ID | 329753939 |
| MDL Number | MFCD00003284 |
| SMILES | [H]C(=O)N(C)C |
| InChI | 1S/C3H7NO/c1-4(2)3-5/h3H,1-2H3 |
| InChI Key | ZMXDDKWLCZADIW-UHFFFAOYSA-N |
| Beilstein/REAXYS | 605365 |
| NACRES Code | NA.07 |
| UNSPSC | 12352111 |
| Hazard Symbols | 3 |
| MSDS | msds/15045_1_68_12_2.pdf |
| Bioactivity | N,N-Dimethylformamide (DMF) is widely used as a drug solvent. N,N-Dimethylformamide is a dipolar protophilic solvent with physicochemical properties that makes it suitable as solvent for capillary electrophoresis (CE)[1][2]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others In Vivo N,N-Dimethylformamide (DMF; N-Formyldimethylamine) has hepatotoxic properties[3]. References [1]. Porras SP, et al. Capillary electrophoresis in N,N-dimethylformamide. Electrophoresis. 2005;26(17):3279-3291. [2]. Varma RK, et al. Solvent artifacts likely to be induced by dimethylformamide. Indian J Physiol Pharmacol. 1986;30(3):248-254. [3]. Mráz J, et al. Investigation of the mechanistic basis of N,N-dimethylformamide toxicity. Metabolism of N,N-dimethylformamide and its deuterated isotopomers by cytochrome P450 2E1. Chem Res Toxicol. 1993;6(2):197-207. Chemical & Physical Properties Density 0.948 g/mL at 20 °C Boiling Point 153 °C(lit.) Melting Point -61 °C Molecular Formula C3H7NO Molecular Weight 73.09380 Flash Point 136 °F Exact Mass 73.05280 PSA 20.31000 LogP 0.34030 Vapour density 2.5 (vs air) Index of Refraction n20/D 1.430(lit.) InChIKey ZMXDDKWLCZADIW-UHFFFAOYSA-N SMILES CN(C)C=O Water Solubility soluble |
| Use of | N,N-Dimethylformamide (DMF) is widely used as a drug solvent. N,N-Dimethylformamide is a dipolar protophilic solvent with physicochemical properties that makes it suitable as solvent for capillary electrophoresis (CE)[1][2]. Properties Articles820 Name N,N-dimethylformamide Synonym More Synonyms N,N-Dimethylformamide Biological Activity Description N,N-Dimethylformamide (DMF) is widely used as a drug solvent. N,N-Dimethylformamide is a dipolar protophilic solvent with physicochemical properties that makes it suitable as solvent for capillary electrophoresis (CE)[1][2]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others In Vivo N,N-Dimethylformamide (DMF; N-Formyldimethylamine) has hepatotoxic properties[3]. References [1]. Porras SP, et al. Capillary electrophoresis in N,N-dimethylformamide. Electrophoresis. 2005;26(17):3279-3291. [2]. Varma RK, et al. Solvent artifacts likely to be induced by dimethylformamide. Indian J Physiol Pharmacol. 1986;30(3):248-254. Chemical & Physical Properties Molecular Formula C3H7NO Exact Mass 73.05280 PSA 20.31000 LogP 0.34030 Vapour density 2.5 (vs air) InChIKey ZMXDDKWLCZADIW-UHFFFAOYSA-N SMILES CN(C)C=O Water Solubility soluble |
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