CAS Number38275-34-2
Synonyms2-methanesulfonyl-5-chloro-4-pyrimidinecarboxylic acid; 2-methylsulfonyl-5-chloro-4-pyrimidine carboxylic acid; 2-methylsulfonyl-5-chloropyrimidine-4-carboxylic acid; 5-chloro-2-methanesulfonyl-pyrimidine-4-carboxylic acid; 4-carboxy-5-chloro-2-methylsulfonylpyrimidine; PK11007
Molecular FormulaC6H5ClN2O4S
Molecular Weight236.64
Purity96+%
Appearancepowder
EINECS0
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 38275-34-2 |
| Catalog No. | 2A-0144267 |
| Chinese Name | 5-氯-2-(甲磺酰基)嘧啶-4-羧酸 |
| Synonyms | 2-methanesulfonyl-5-chloro-4-pyrimidinecarboxylic acid; 2-methylsulfonyl-5-chloro-4-pyrimidine carboxylic acid; 2-methylsulfonyl-5-chloropyrimidine-4-carboxylic acid; 5-chloro-2-methanesulfonyl-pyrimidine-4-carboxylic acid; 4-carboxy-5-chloro-2-methylsulfonylpyrimidine; PK11007 |
| Molecular Formula | C6H5ClN2O4S |
| Molecular Weight | 236.64 |
| Purity | 96+ |
| Appearance | powder |
| Storage Condition | -20℃ |
| Application | PK11007 is a compound that targets p53 and fights tumors by reactivating unstable p53. |
| EINECS | 0 |
| HTC | 2933599090 |
| UN(IATA) | 0 |
| MDL Number | C6H5ClN2O4S |
| SMILES | CS(=O)(=O)c1ncc(Cl)c(C(=O)O)n1 |
| InChI Key | WZUPWJVRWIVWEF-UHFFFAOYSA-N |
| MSDS | msds/144267_1_38275_34_2.pdf |
| Use of | PK11007 is a p53 targeting compound, has anti-tumor activities through activation of unstable p53. Properties Name 5-chloro-2-methylsulfonylpyrimidine-4-carboxylic acid Synonym More Synonyms PK11007 Biological Activity Description PK11007 is a p53 targeting compound, has anti-tumor activities through activation of unstable p53. Related Catalog Research Areas >> Cancer References [1]. Bauer MR, et al. 2-Sulfonylpyrimidines: Mild alkylating agents with anticancer activity toward p53-compromised cells. Proc Natl Acad Sci U S A. 2016 Sep 6;113(36):E5271-80. Chemical & Physical Properties Exact Mass 235.96600 PSA 105.60000 LogP 1.31250 InChIKey WZUPWJVRWIVWEF-UHFFFAOYSA-N SMILES CS(=O)(=O)c1ncc(Cl)c(C(=O)O)n1 Storage condition -20℃ Safety Information HS Code 2933599090 Precursor & DownStream Precursor 1 CAS#:61727-33-1 5-Chloro-2-(met... DownStream 1 CAS#:38275-47-7 2-(Methylsulfon... |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| Related Products in Heterocyclic Building Blocks | ||
|---|---|---|
| 5-CHLORO-2,3-DIMETHOXYPYRIDINE | 284040-73-9 | 2A-0144219 |
| 5-CHLORO-2,3-DIPHENYL-1H-INDOLE | 52598-02-4 | 2A-0144221 |
| 5-CHLORO-2-(1-METHYLHYDRAZINYL)-3-(TRIFLUOROMETHYL)PYRIDINE | 175205-60-4 | 2A-0144243 |
| 5-CHLORO-2-(2-CHLOROPHENYL)-1H-BENZO[D]IMIDAZOLE | 14225-75-3 | 2A-0144246 |
| 5-CHLORO-2-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-INDOLE | 1256358-91-4 | 2A-0144252 |
| 5-CHLORO-2-(S-METHYLSULFINIMIDOYL)-3-(TRIFLUOROMETHYL)PYRIDINE 2,4,6-TRIMETHYLBENZENESULFONATE | 175203-07-3 | 2A-0144275 |
| 5-CHLORO-2-(TRIFLUOROMETHYL)BENZO[D]OXAZOLE | 93416-20-7 | 2A-0144279 |
| 5-CHLORO-2-ETHOXY-3-NITROPYRIDINE | 886373-32-6 | 2A-0144289 |
| 5-CHLORO-2-ETHYNYLPYRIDINE | 1196153-33-9 | 2A-0144296 |
| 5-CHLORO-2-ETHYNYLPYRIMIDINE | 1196156-95-2 | 2A-0144297 |
| Browse all Heterocyclic Building Blocks products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS