CAS Number141-05-9
Synonymscis-Diethyl maleate; MFCD00009191; diethyl L-malic ester; Diethyl L-(-)-Malate; (S)-(-)-Aepfelsaeure-diethylester; cis-Propenoic acid diethyl ester; Maleic acid, diethyl ester; EINECS 205-451-9; (S)-malic acid diethyl ester; diethylmaleate; Diethyl (2Z)-2-butenedioate; Diethyl (2Z)-but-2-enedioate; L-(-)-Malic Acid Diethyl Ester; (S)-(-)-diethyl 2-hydroxybutandioate; diethyl (Z)-but-2-enedioate; diethyl (2Z)but-2-ene-1,4-dioate; 1,4-diethyl (2Z)-but-2-enedioate; 2-Butenedioic acid (2Z)-, diethyl ester; 2-Butenedioic acid (Z)-, diethyl ester; maleic acid diethyl ester; Ethyl Maleate; (2S)-2-hydroxybutanedioic acid diethylester; Diethyl maleate; diethyl (S)-malate; (Z)-2-Butenedioic acid diethyl ester
Molecular FormulaC2H5OCOCH=CHCOOC2H5
Molecular Weight172.18
Purity97%
Density1.1±0.1 g/cm3
Boiling Point225 °C (lit.)
Melting Point−10 °C (lit.)
Appearanceliquid
EINECS205-451-9
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 141-05-9 |
| Catalog No. | 2A-9014268 |
| Chinese Name | 顺丁烯二甲酸二乙酯 |
| Synonyms | cis-Diethyl maleate; MFCD00009191; diethyl L-malic ester; Diethyl L-(-)-Malate; (S)-(-)-Aepfelsaeure-diethylester; cis-Propenoic acid diethyl ester; Maleic acid, diethyl ester; EINECS 205-451-9; (S)-malic acid diethyl ester; diethylmaleate; Diethyl (2Z)-2-butenedioate; Diethyl (2Z)-but-2-enedioate; L-(-)-Malic Acid Diethyl Ester; (S)-(-)-diethyl 2-hydroxybutandioate; diethyl (Z)-but-2-enedioate; diethyl (2Z)but-2-ene-1,4-dioate; 1,4-diethyl (2Z)-but-2-enedioate; 2-Butenedioic acid (2Z)-, diethyl ester; 2-Butenedioic acid (Z)-, diethyl ester; maleic acid diethyl ester; Ethyl Maleate; (2S)-2-hydroxybutanedioic acid diethylester; Diethyl maleate; diethyl (S)-malate; (Z)-2-Butenedioic acid diethyl ester |
| Molecular Formula | C2H5OCOCH=CHCOOC2H5 |
| Molecular Weight | 172.18 |
| Purity | 97 |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 225 °C (lit.) |
| Melting Point | −10 °C (lit.) |
| Appearance | liquid |
| Water Solubility | insoluble |
| Storage Condition | Store in a cool, dry and ventilated place. Pay att |
| Application | Diethyl maleate is a maleate ester formed by the formal condensation of two carboxyl groups of maleic acid with ethanol. Diethyl maleate (DEM) is a thiol-reactive α,β-unsaturated carbonyl compound tha |
| EINECS | 205-451-9 |
| HTC | 29171990 |
| PubChem ID | 24894328 |
| MDL Number | MFCD00009191 |
| SMILES | CCOC(=O)\C=C/C(=O)OCC |
| InChI | 1S/C8H12O4/c1-3-11-7(9)5-6-8(10)12-4-2/h5-6H,3-4H2,1-2H3/b6-5- |
| InChI Key | IEPRKVQEAMIZSS-WAYWQWQTSA-N |
| Beilstein/REAXYS | 1100825 |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| MSDS | msds/14268_1_141_05_9.pdf |
| Bioactivity | Diethyl maleate is a maleate ester resulting from the formal condensation of both carboxy groups of maleic acid with ethanol. Diethyl maleate (DEM), a thiol-reactive α,β-unsaturated carbonyl compound, depletes glutathione (GSH) in exposed cells[1]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [1]. Andrea Gille, et al. Nuclear trapping of inactive FOXO1 by the Nrf2 activator diethyl maleate. Redox Biol. 2019 Jan;20:19-27. Chemical & Physical Properties Density 1.1±0.1 g/cm3 Boiling Point 214.0±0.0 °C at 760 mmHg Melting Point −10 °C(lit.) Molecular Formula C8H12O4 Molecular Weight 172.178 Flash Point 93.3±0.0 °C Exact Mass 172.073563 PSA 52.60000 LogP 1.68 Vapour density 5.93 (vs air) Vapour Pressure 0.2±0.4 mmHg at 25°C Index of Refraction 1.443 InChIKey IEPRKVQEAMIZSS-WAYWQWQTSA-N SMILES CCOC(=O)C=CC(=O)OCC Stability Stable. Combustible. Incompatible with oxidizing agents, bases, acids, reducing agents. Water Solubility insoluble |
| Use of | Diethyl maleate is a maleate ester resulting from the formal condensation of both carboxy groups of maleic acid with ethanol. Diethyl maleate (DEM), a thiol-reactive α,β-unsaturated carbonyl compound, depletes glutathione (GSH) in exposed cells[1]. Properties Articles37 Name diethyl maleate Synonym More Synonyms diethylmaleate Biological Activity Description Diethyl maleate is a maleate ester resulting from the formal condensation of both carboxy groups of maleic acid with ethanol. Diethyl maleate (DEM), a thiol-reactive α,β-unsaturated carbonyl compound, depletes glutathione (GSH) in exposed cells[1]. Related Catalog Research Areas >> Others Signaling Pathways >> Others >> Others References [1]. Andrea Gille, et al. Nuclear trapping of inactive FOXO1 by the Nrf2 activator diethyl maleate. Redox Biol. 2019 Jan;20:19-27. Chemical & Physical Properties Molecular Formula C8H12O4 Exact Mass 172.073563 PSA 52.60000 Vapour density 5.93 (vs air) Index of Refraction 1.443 InChIKey IEPRKVQEAMIZSS-WAYWQWQTSA-N SMILES CCOC(=O)C=CC(=O)OCC Stability Stable. Combustible. Incompatible with oxidizing agents, bases, acids, reducing agents. Water Solubility insoluble |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Chemical name |
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