CAS Number169590-41-4
Synonymsderacoxib; 4-[3-(difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)pyrazol-1-yl]benzenesulfonamide; 4-(3-(Difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1H-pyrazol-1-yl)benzenesulfonamide; 4-[3-(Difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1H-pyrazol-1-yl]benzenesulfonamide
Molecular FormulaC17H14F3N3O3S
Molecular Weight397.372
Purity96+%
Density1.5±0.1 g/cm3
Boiling Point575.5±60.0 °C at 760 mmHg
Appearancepowder
EINECS0
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 169590-41-4 |
| Catalog No. | 2A-0134799 |
| Chinese Name | 地拉考昔 |
| Synonyms | deracoxib; 4-[3-(difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)pyrazol-1-yl]benzenesulfonamide; 4-(3-(Difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1H-pyrazol-1-yl)benzenesulfonamide; 4-[3-(Difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1H-pyrazol-1-yl]benzenesulfonamide |
| Molecular Formula | C17H14F3N3O3S |
| Molecular Weight | 397.372 |
| Purity | 96+ |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 575.5±60.0 °C at 760 mmHg |
| Appearance | powder |
| Storage Condition | -20℃ |
| Application | Deracoxib is a COX-2 selective inhibitor, a non-narcotic, non-steroidal anti-inflammatory compound. |
| EINECS | 0 |
| HTC | 2935009090 |
| UN(IATA) | 0 |
| SMILES | COc1ccc(-c2cc(C(F)F)nn2-c2ccc(S(N)(=O)=O)cc2)cc1F |
| InChI | InChI=1S/C17H14F3N3O3S/c1-26-16-7-2-10(8-13(16)18)15-9-14(17(19)20)22-23(15)11-3-5-12(6-4-11)27(21,24)25/h2-9,17H,1H3,(H2,21,24,25) |
| InChI Key | WAZQAZKAZLXFMK-UHFFFAOYSA-N |
| Use of | Properties Name deracoxib Synonym More Synonyms deracoxib Biological Activity Related Catalog Research Areas >> Inflammation/Immunology References [1]. Royals, S.R., et al., Investigation of the effects of deracoxib and piroxicam on the in vitro viability of osteosarcoma cells from dogs. Am J Vet Res, 2005. 66(11): p. 1961-7. [2]. Ustun Alkan, F., et al., The effects of piroxicam and deracoxib on canine mammary tumour cell line. ScientificWorldJournal, 2012. 2012: p. 976740. [3]. Bienhoff, S.E., et al., Efficacy and safety of deracoxib for control of postoperative pain and inflammation associated with soft tissue surgery in dogs. Vet Surg, 2012. 41(3): p. 336-44. [4]. McMillan, S.K., et al., Antitumor effects of deracoxib treatment in 26 dogs with transitional cell carcinoma of the urinary bladder. J Am Vet Med Assoc, 2011. 239(8): p. 1084-9. Chemical & Physical Properties Molecular Formula C17H14F3N3O3S Exact Mass 397.070801 PSA 95.59000 Index of Refraction 1.610 InChIKey WAZQAZKAZLXFMK-UHFFFAOYSA-N Storage condition -20℃ Safety Information HS Code 2935009090 Synthetic Route 4,4-difluoro-1-... CAS#:170570-77-1 CAS#:169590-41-4 Literature: G.D. Searle and Co. Patent: US5760068 A1, 1998 ; 4-Hydrazinobenz... CAS#:17852-52-7 4,4-difluoro-1-... CAS#:170570-77-1 CAS#:169590-41-4 Literature: G. D. Searle and Co. Patent: US6342510 B1, 2002 ; Location in patent: Page column 28 - 29 ; ethyldifluoracetat CAS#:454-31-9 3′-Fluoro-4′-me... CAS#:455-91-4 CAS#:169590-41-4 Literature: US5892053 A1, ; Precursor & DownStream Precursor 4 CAS#:170570-77-1 4,4-difluoro-1-... CAS#:17852-52-7 4-Hydrazinobenz... CAS#:454-31-9 ethyldifluoracetat CAS#:455-91-4 3′-Fluoro-4′-me... DownStream 0 |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 35.0% |
| Transport Info | Product name: Summary 2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0% |
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