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Home > Products > Pharmaceutical R&D Materials > Heterocyclic Building Blocks > 4-(2-(6-METHYLPYRIDIN-2-YL)-5,6-DIHYDRO-4H-PYRROLO[1,2-B]PYRAZOL-3-YL)QUINOLINE-6-CARBOXAMIDE
4-(2-(6-METHYLPYRIDIN-2-YL)-5,6-DIHYDRO-4H-PYRROLO[1,2-B]PYRAZOL-3-YL)QUINOLINE-6-CARBOXAMIDE structure, CAS 700874-72-2

4-(2-(6-METHYLPYRIDIN-2-YL)-5,6-DIHYDRO-4H-PYRROLO[1,2-B]PYRAZOL-3-YL)QUINOLINE-6-CARBOXAMIDE

CAS Number700874-72-2

Synonyms2-(6-Methyl-pyridin-2-yl)-1-quinoxalin-6-yl-ethanone; 4-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamide; 2-(6-methyl-pyridin-2-yl)-3-(6-amido-quinolin-4-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole; LY2157299; LY-2157299; LY 2157299; Galunisertib; 4-[2-(6-Methyl-2-pyridinyl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-6-quinolinecarboxamide; 6-[2-(6-Methylpyridin-2-yl)-acetyl]quinoxaline

Molecular FormulaC22H19N5O

Molecular Weight369.42

Purity≥98 (HPLC)%

Density1.4±0.1 g/cm3

Boiling Point619.0±55.0 °C at 760 mmHg

Melting Point

Flash Point

Appearancepowder

EINECS0

MSDSChineseEnglish

Symbol

Signal Word

Cat. No.: 2A-0134420 Purity: ≥98 (HPLC)%
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Quality Control of [ 700874-72-2 ] Purity: ≥98 (HPLC)% SDS Specification MoL

COA NMR CNMR HPLC LC-MS
Chemical & Physical Properties
CAS Number700874-72-2
Catalog No.2A-0134420
Chinese NameGalunisertib (LY2157299)
Synonyms2-(6-Methyl-pyridin-2-yl)-1-quinoxalin-6-yl-ethanone; 4-[2-(6-methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamide; 2-(6-methyl-pyridin-2-yl)-3-(6-amido-quinolin-4-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole; LY2157299; LY-2157299; LY 2157299; Galunisertib; 4-[2-(6-Methyl-2-pyridinyl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-6-quinolinecarboxamide; 6-[2-(6-Methylpyridin-2-yl)-acetyl]quinoxaline
Molecular FormulaC22H19N5O
Molecular Weight369.42
Purity≥98 (HPLC)
Density1.4±0.1 g/cm3
Boiling Point619.0±55.0 °C at 760 mmHg
Appearancepowder
Storage Condition2-8°C
ApplicationGalunisertib (LY2157299) is a selective TGF-β receptor inhibitor with an IC50 of 56 nM.
EINECS0
HTC29334900
UN(IATA)0
MDL NumberMFCD12923319
SMILES[n]21nc(c(c2CCC1)c4c5c(ncc4)ccc(c5)C(=O)N)c3nc(ccc3)C
InChI1S/C22H19N5O/c1-13-4-2-5-18(25-13)21-20(19-6-3-11-27(19)26-21)15-9-10-24-17-8-7-14(22(23)28)12-16(15)17/h2,4-5,7-10,12H,3,6,11H2,1H3,(H2,23,28)
InChI KeyIVRXNBXKWIJUQB-UHFFFAOYSA-N
NACRES CodeNA.77
UNSPSC12352200
MSDSmsds/134420_1_700874_72_2.pdf
Transport InfoProduct name: LY2157299
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