| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1111897-60-9 |
| Catalog No. | 2A-0134003 |
| Chinese Name | 7,3',4'-三羟基-3-苄基-2H-苯并吡喃 |
| Synonyms | 4-[(7-Hydroxy-2H-chromen-3-yl)methyl]-1,2-benzenediol; W2750; 7,3',4'-Trihydroxy-3-benzyl-2H-chromene |
| Molecular Formula | C16H14O4 |
| Molecular Weight | 270.280 |
| Purity | 96+ |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 540.8±50.0 °C at 760 mmHg |
| Appearance | powder |
| Storage Condition | 2-8℃, sealed, dry |
| Application | 7,3',4'-Trihydroxy-3-benzyl-2H-tryptophan is a reversible, non-competitive neuraminidase (NA) inhibitor. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene can be isolated from the dried heartwood of Caesalpinia |
| EINECS | 0 |
| HTC | 2932999099 |
| UN(IATA) | 0 |
| SMILES | Oc1ccc2c(c1)OCC(Cc1ccc(O)c(O)c1)=C2 |
| InChI Key | HPLBTDJMPUFEPF-UHFFFAOYSA-N |
| Use of | 7,3',4'-Trihydroxy-3-benzyl-2H-chromene is an reversible noncompetitive neuraminidase (NA) inhibitor. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene can be isolated from the dried heartwood of Caesalpinia sappan L. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene has potent NAs inhibitory activities with IC50 values of 34.6 µM [H1N1], 39.5 µM [H3N2], and 50.5µM [H9N2], respectively. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene can be used for the research of influenza virus[1][2]. Properties Name 4-[(7-hydroxy-2H-chromen-3-yl)methyl]benzene-1,2-diol Synonyms More Synonyms 7,3',4'-Trihydroxy-3-benzyl-2H-chroMene Biological Activity Description 7,3',4'-Trihydroxy-3-benzyl-2H-chromene is an reversible noncompetitive neuraminidase (NA) inhibitor. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene can be isolated from the dried heartwood of Caesalpinia sappan L. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene has potent NAs inhibitory activities with IC50 values of 34.6 µM [H1N1], 39.5 µM [H3N2], and 50.5µM [H9N2], respectively. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene can be used for the research of influenza virus[1][2]. Related Catalog Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Infection Research Areas >> Inflammation/Immunology IC50: 34.6 µM [H1N1], 39.5 µM [H3N2], and 50.5 µM [H9N2][1]. In Vitro 7,3',4'-Trihydroxy-3-benzyl-2H-chromene has potent NAs inhibitory activity with IC50 values of 34.6 µM [H1N1], 39.5 µM [H3N2] and 50.5 µM respectively. [H9N2][1]. References [1]. Hyung Jae Jeong, et al. Homoisoflavonoids from Caesalpinia sappan displaying viral neuraminidases inhibition. Biol Pharm Bull. 2012;35(5):786-90. [2]. Huanxin Zhao, et al. A new homoisoflavan from Caesalpinia sappan. J Nat Med. 2008 Jul;62(3):325-7. Chemical & Physical Properties Molecular Formula C16H14O4 Exact Mass 270.089203 PSA 69.92000 Index of Refraction 1.702 InChIKey HPLBTDJMPUFEPF-UHFFFAOYSA-N Safety Information HS Code 2932999099 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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