CAS Number130-15-4
Synonymsa-Naphthoquinone; 1,4-Naphthalenedione; naphthoquinone; α-Naphthoquinone; Hydronaphthoquinone; naphthalene-1,4-dione; para-naphthoquinone; 1,4-Hydronaphthoquinone; 1,4-Naphthoquinone; 1,4-naphthalene-dione; MFCD00001676; EINECS 204-977-6
Molecular FormulaC10H6O2
Molecular Weight158.15
Purity97%
Density1.3±0.1 g/cm3
Boiling Point297.9±40.0 °C at 760 mmHg
Melting Point119-122 °C (lit.)
Appearancepowder
EINECS204-977-6
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 130-15-4 |
| Catalog No. | 2A-9013095 |
| Chinese Name | 1,4-萘醌 |
| Synonyms | a-Naphthoquinone; 1,4-Naphthalenedione; naphthoquinone; α-Naphthoquinone; Hydronaphthoquinone; naphthalene-1,4-dione; para-naphthoquinone; 1,4-Hydronaphthoquinone; 1,4-Naphthoquinone; 1,4-naphthalene-dione; MFCD00001676; EINECS 204-977-6 |
| Molecular Formula | C10H6O2 |
| Molecular Weight | 158.15 |
| Purity | 97 |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 297.9±40.0 °C at 760 mmHg |
| Melting Point | 119-122 °C (lit.) |
| Appearance | powder |
| Water Solubility | insoluble |
| Storage Condition | Room temperature, flammable area |
| Packaging | I |
| Application | 1,4-Naphthoquinone is a potential pharmacophore group that inhibits the activity of monoamine oxidase MAO and DNA topoisomerase. DNA topoisomerase activity is related to anti-tumor activity. |
| EINECS | 204-977-6 |
| HTC | 29146910 |
| PubChem ID | 24849257 |
| MDL Number | MFCD00001676 |
| SMILES | O=C1C=CC(=O)c2ccccc12 |
| InChI | 1S/C10H6O2/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6H |
| InChI Key | FRASJONUBLZVQX-UHFFFAOYSA-N |
| Beilstein/REAXYS | 878524 |
| NACRES Code | NA.22 |
| UNSPSC | 12352100 |
| Hazard Symbols | 6.1 |
| MSDS | msds/13095_1_130_15_4.pdf |
| Bioactivity | 1,4-Naphthoquinone is a potential pharmacophore for inhibition of both MAO (monoamine oxidase) and DNA topoisomerase activities, this latter associated with antitumor activity[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Others >> Others References [1]. Coelho-Cerqueira E, et al. Beyond topoisomerase inhibition: antitumor 1,4-naphthoquinones as potential inhibitors of human monoamine oxidase. Chem Biol Drug Des. 2014 Apr;83(4):401-10. Chemical & Physical Properties Density 1.3±0.1 g/cm3 Boiling Point 297.9±40.0 °C at 760 mmHg Melting Point 119-122 °C(lit.) Molecular Formula C10H6O2 Molecular Weight 158.153 Flash Point 111.2±24.3 °C Exact Mass 158.036774 PSA 34.14000 LogP 1.79 Vapour Pressure 0.0±0.6 mmHg at 25°C Index of Refraction 1.617 InChIKey FRASJONUBLZVQX-UHFFFAOYSA-N SMILES O=C1C=CC(=O)c2ccccc21 Stability Stable. Incompatible with strong reducing agents, strong oxidizing agents. Water Solubility insoluble |
| Use of | 1,4-Naphthoquinone is a potential pharmacophore for inhibition of both MAO (monoamine oxidase) and DNA topoisomerase activities, this latter associated with antitumor activity[1]. Properties Articles41 Name 1,4-naphthoquinone Synonym More Synonyms 1,4-naphthoquinone Biological Activity Description 1,4-Naphthoquinone is a potential pharmacophore for inhibition of both MAO (monoamine oxidase) and DNA topoisomerase activities, this latter associated with antitumor activity[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> Others >> Others References [1]. Coelho-Cerqueira E, et al. Beyond topoisomerase inhibition: antitumor 1,4-naphthoquinones as potential inhibitors of human monoamine oxidase. Chem Biol Drug Des. 2014 Apr;83(4):401-10. Chemical & Physical Properties Molecular Formula C10H6O2 Exact Mass 158.036774 PSA 34.14000 Index of Refraction 1.617 InChIKey FRASJONUBLZVQX-UHFFFAOYSA-N Stability Stable. Incompatible with strong reducing agents, strong oxidizing agents. Water Solubility insoluble |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 5.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 0.0% |
| MSDS Transport Info | Module 14. Shipping information United Nations classification: Item 1 Poisons. UN number: 2811 Proper Shipping Name: Toxic Solid, Organic, Not Otherwise Specified Packing grade: I Marine pollutants: Y |
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