| Chemical & Physical Properties | |
|---|---|
| CAS Number | 104774-87-0 |
| Catalog No. | 2A-0127074 |
| Chinese Name | 3-三氟甲基苯丙胺 |
| Synonyms | 3-[3-(Trifluoromethyl)phenyl]-1-propanamine |
| Molecular Formula | C10H12N1F3 |
| Molecular Weight | 203.21 |
| Purity | 96+ |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 222.2±40.0 °C at 760 mmHg |
| Storage Condition | 2-8°C, sealed, dry |
| Application | Cinacalcet metabolite M4 is a metabolite of Cinacalcet. Cinacalcet is an orally available Ca receptor (CaR) agonist for cardiovascular disease. |
| EINECS | 0 |
| HTC | 2921499090 |
| UN(IATA) | 0 |
| PubChem ID | 32593025 |
| MDL Number | MFCD06213071 |
| SMILES | NCCCc1cccc(C(F)(F)F)c1 |
| InChI | InChI=1S/C10H12F3N/c11-10(12,13)9-5-1-3-8(7-9)4-2-6-14/h1,3,5,7H,2,4,6,14H2 |
| InChI Key | JMTLMFBJIQWJPW-UHFFFAOYSA-N |
| Use of | Cinacalcet metabolite M4 is a metabolite of Cinacalcet. Cinacalcet is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease[1][2]. Properties Name 3-[3-(trifluoromethyl)phenyl]propan-1-amine Synonym More Synonyms Cinacalcet metabolite M4 Biological Activity Description Cinacalcet metabolite M4 is a metabolite of Cinacalcet. Cinacalcet is an orally active, allosteric agonist of Ca receptor (CaR), used for cardiovascular disease[1][2]. Related Catalog Research Areas >> Cardiovascular Disease References [1]. Kumar GN, et al. Metabolism and disposition of calcimimetic agent cinacalcet HCl in humans and animalmodels. Drug Metab Dispos. 2004 Dec;32(12):1491-500. [2]. Bushinsky DA, et al. Effect of cinacalcet on urine calcium excretion and supersaturation in genetic hypercalciuric stone-forming rats. Kidney Int. 2006 May;69(9):1586-92. Chemical & Physical Properties Molecular Formula C10H12F3N Exact Mass 203.092178 PSA 26.02000 Index of Refraction 1.468 InChIKey JMTLMFBJIQWJPW-UHFFFAOYSA-N Safety Information Hazard Codes Xi HS Code 2921499090 Synthetic Route 3-(3-(trifluoro... CAS#:535-53-5 Cinacalcet meta... CAS#:104774-87-0 Literature: Wang, Xin; Chen, Ying; Crockett, Richard; Briones, Jorge; Yan, Tony; Orihuela, Carlos; Zhi, Benxin; Ng, John Tetrahedron Letters, 2004 , vol. 45, # 45 p. 8355 - 8358 3-[3-(trifluoro... CAS#:60689-14-7 Cinacalcet meta... CAS#:104774-87-0 Literature: Tetrahedron Letters, , vol. 45, # 45 p. 8355 - 8358 3-(trifluoromet... CAS#:64380-24-1 Cinacalcet meta... CAS#:104774-87-0 Literature: Tetrahedron Letters, , vol. 45, # 45 p. 8355 - 8358 Precursor & DownStream Precursor 5 CAS#:535-53-5 3-(3-(trifluoro... CAS#:60689-14-7 3-[3-(trifluoro... CAS#:64380-24-1 3-(trifluoromet... CAS#:93040-58-5 3-(3-(trifluoro... DownStream 0 |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
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