CAS Number515-03-7
SynonymsSCLAREOL(RG); EINECS 208-194-0; SCIADONIC ACID; (1R,2R,8aS)-Decahydro-1-(3-hydroxy-3-methyl-4-pentenyl)-2,5,5,8a-tetramethyl-2-naphthol; labd-14-ene-8,13(R)-diol; MFCD00869558; SCLAREOL,NATURAL; SCAREOL; Sclareol; (-)-sclareol; SCLAREOL(P)
Molecular FormulaC20H36O2
Molecular Weight308.50
Purity98%
Density1.0±0.1 g/cm3
Boiling Point218-220 °C/19 mmHg (lit.)
Melting Point95-100 °C (lit.)
AppearanceWhite fine powder
EINECS208-194-0
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 515-03-7 |
| Catalog No. | 2A-9012404 |
| Chinese Name | 香紫苏醇 |
| Synonyms | SCLAREOL(RG); EINECS 208-194-0; SCIADONIC ACID; (1R,2R,8aS)-Decahydro-1-(3-hydroxy-3-methyl-4-pentenyl)-2,5,5,8a-tetramethyl-2-naphthol; labd-14-ene-8,13(R)-diol; MFCD00869558; SCLAREOL,NATURAL; SCAREOL; Sclareol; (-)-sclareol; SCLAREOL(P) |
| Molecular Formula | C20H36O2 |
| Molecular Weight | 308.50 |
| Purity | 98 |
| Density | 1.0±0.1 g/cm3 |
| Boiling Point | 218-220 °C/19 mmHg (lit.) |
| Melting Point | 95-100 °C (lit.) |
| Appearance | White fine powder |
| Water Solubility | Water solubility: insoluble |
| Storage Condition | Storage, transportation and storage: Packed in car |
| Application | Sclareol is isolated from Salvia sclarea and has anti-cancer activity. Sclareol has strong cytotoxic activity against mouse leukemia (P-388), human epidermal carcinoma (KB), and human leukocytes. Scla |
| EINECS | 208-194-0 |
| HTC | 2906199090 |
| PubChem ID | 24861955 |
| MDL Number | MFCD00869558 |
| SMILES | CC1(C)CCC[C@@]2(C)[C@H]1CC[C@@](C)(O)[C@@H]2CC[C@@](C)(O)C=C |
| InChI | 1S/C20H36O2/c1-7-18(4,21)13-9-16-19(5)12-8-11-17(2,3)15(19)10-14-20(16,6)22/h7,15-16,21-22H,1,8-14H2,2-6H3/t15-,16+,18-,19-,20+/m0/s1 |
| InChI Key | XVULBTBTFGYVRC-HHUCQEJWSA-N |
| Beilstein/REAXYS | 2054148 |
| NACRES Code | NA.22 |
| UNSPSC | 12352002 |
| Hazard Symbols | Transport |
| MSDS | msds/12404_1_515_03_7.pdf |
| Bioactivity | Sclareol is isolated from Salvia sclarea with anticarcinogenic activity. Sclareol shows strong cytotoxic activity against mouse leukemia (P-388), human epidermal carcinoma (KB) cells and human leukemia cell lines. Sclareol induces cell apoptosis[1]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer In Vitro Sclareol is cytotoxic to 13 of 14 human leukemia cell lines tested, with IC50 values ranging from 6.0-24.2 μg/mL, but is not cytotoxic to peripheral blood mononuclear leukocytes within the same dose range[1]. References [1]. Robert Tisserand, et al. Sclareol.Constituent profiles Chemical & Physical Properties Density 1.0±0.1 g/cm3 Boiling Point 398.3±15.0 °C at 760 mmHg Melting Point 95-100 °C(lit.) Molecular Formula C20H36O2 Molecular Weight 308.499 Flash Point 169.1±15.0 °C Exact Mass 308.271515 PSA 40.46000 LogP 5.54 Vapour Pressure 0.0±2.1 mmHg at 25°C Index of Refraction 1.490 InChIKey XVULBTBTFGYVRC-HHUCQEJWSA-N SMILES C=CC(C)(O)CCC1C(C)(O)CCC2C(C)(C)CCCC21C Storage condition 2-8C |
| Use of | Sclareol is isolated from Salvia sclarea with anticarcinogenic activity. Sclareol shows strong cytotoxic activity against mouse leukemia (P-388), human epidermal carcinoma (KB) cells and human leukemia cell lines. Sclareol induces cell apoptosis[1]. Properties Articles27 Name sclareol Synonym More Synonyms Sclareol Biological Activity Description Sclareol is isolated from Salvia sclarea with anticarcinogenic activity. Sclareol shows strong cytotoxic activity against mouse leukemia (P-388), human epidermal carcinoma (KB) cells and human leukemia cell lines. Sclareol induces cell apoptosis[1]. Related Catalog Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer In Vitro Sclareol is cytotoxic to 13 of 14 human leukemia cell lines tested, with IC50 values ranging from 6.0-24.2 μg/mL, but is not cytotoxic to peripheral blood mononuclear leukocytes within the same dose range[1]. References [1]. Robert Tisserand, et al. Sclareol.Constituent profiles Chemical & Physical Properties Molecular Formula C20H36O2 Exact Mass 308.271515 PSA 40.46000 Index of Refraction 1.490 InChIKey XVULBTBTFGYVRC-HHUCQEJWSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 5.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 95.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available The above information is believed to be correct, but is not all-inclusive and should be used as a guide only. The information in this document is based on our current knowledge and is Correct safety instructions apply to this product. This information does not represent a warranty as to the properties of this product. See reverse side of invoice or packing slip. |
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