| Chemical & Physical Properties | |
|---|---|
| CAS Number | 60569-19-9 |
| Catalog No. | 2A-9012168 |
| Chinese Name | 丙哌维林 |
| Synonyms | Propiverine |
| Molecular Formula | C23H29NO3 |
| Molecular Weight | 403.94 |
| Purity | ≥98 (HPLC) |
| Density | 1.08 g/cm3 |
| Boiling Point | 468.8ºC at 760 mmHg |
| Appearance | powder |
| Application | Proverine is a powerful anti-venom drug. Profoline inhibits cellular calcium influx, thereby reducing muscle spasms. Profoline has neurotrophic and myotrophic effects on bladder smooth muscle. Profoli |
| HTC | 2933399090 |
| SMILES | [Cl-].[N+H]1(CCC(CC1)OC(=O)C(OCCC)(c3ccccc3)c2ccccc2)C |
| InChI | 1S/C23H29NO3.ClH/c1-3-18-26-23(19-10-6-4-7-11-19,20-12-8-5-9-13-20)22(25)27-21-14-16-24(2)17-15-21;/h4-13,21H,3,14-18H2,1-2H3;1H |
| InChI Key | KFUJMHHNLGCTIJ-UHFFFAOYSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| MSDS | msds/12168_1_60569_19_9.pdf |
| Use of | Propiverine is a potent antimuscarinic agent. Propiverine inhibits cellular calcium influx, thereby diminishing muscle spasm. Propiverine has neurotropic and musculotropic effects on the urinary bladder smooth muscle. Propiverine can used for overactive bladder (OAB) research[1][2]. Properties Name (1-Methyl-4-piperidyl) 2,2-diphenyl-2-propoxy-acetate Synonym More Synonyms Biological Activity Description Propiverine is a potent antimuscarinic agent. Propiverine inhibits cellular calcium influx, thereby diminishing muscle spasm. Propiverine has neurotropic and musculotropic effects on the urinary bladder smooth muscle. Propiverine can used for overactive bladder (OAB) research[1][2]. Related Catalog Signaling Pathways >> Neuronal Signaling >> mAChR Signaling Pathways >> GPCR/G Protein >> mAChR Research Areas >> Neurological Disease References [1]. McKeage K. Propiverine: a review of its use in the treatment of adults and children with overactive bladder associated with idiopathic or neurogenic detrusor overactivity, and in men with lower urinary tract symptoms. Clin Drug Investig. 2013 Jan;33(1):71-91. [2]. Madersbacher H, Mürtz G. Efficacy, tolerability and safety profile of propiverine in the treatment of the overactive bladder (non-neurogenic and neurogenic). World J Urol. 2001 Nov;19(5):324-35. Chemical & Physical Properties Molecular Formula C23H29NO3 Exact Mass 367.21500 PSA 38.77000 LogP 3.93210 Index of Refraction 1.57 InChIKey QPCVHQBVMYCJOM-UHFFFAOYSA-N Safety Information HS Code 2933399090 Synthetic Route Total: 1 Page Propiverine hyd... CAS#:54556-98-8 1-METHYLPIPERID... CAS#:60569-19-9 Precursor & DownStream Precursor 1 CAS#:54556-98-8 Propiverine hyd... DownStream 1 CAS#:3608-67-1 enpiperate |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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