CAS Number34183-22-7
Synonyms1-{2-[2-Hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one hydrochloride (1:1); Propafenone hydrochloride; 1-[2-(2-Hydroxy-3-(propylamino)propoxy)phenyl]-3-phenyl-1-propanone hydrochloride; Rythmol; 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenylpropan-1-one hydrochloride; 1-propanone, 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-, hydrochloride; 2'-[2-Hydroxy-3-(propylamino)propoxy]-3-phenylpropiophenone Hydrochloride; 1-[2-[2-Hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-1-propanone Hydrochloride; (±)-Propafenone Hydrochloride; 1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one hydrochloride; Arythmol; 1-Propanone, 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-, hydrochloride (1:1); EINECS 251-867-9; 1-{2-[2-Hydroxy-3-(propylamino)
Molecular FormulaC21H28ClNO3
Molecular Weight377.90
Purity98%
Boiling Point519.6ºC at 760 mmHg
Melting Point165-1670C
Appearancewhite solid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 34183-22-7 |
| Catalog No. | 2A-9012152 |
| Chinese Name | 心律平 |
| Synonyms | 1-{2-[2-Hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one hydrochloride (1:1); Propafenone hydrochloride; 1-[2-(2-Hydroxy-3-(propylamino)propoxy)phenyl]-3-phenyl-1-propanone hydrochloride; Rythmol; 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenylpropan-1-one hydrochloride; 1-propanone, 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-, hydrochloride; 2'-[2-Hydroxy-3-(propylamino)propoxy]-3-phenylpropiophenone Hydrochloride; 1-[2-[2-Hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-1-propanone Hydrochloride; (±)-Propafenone Hydrochloride; 1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one hydrochloride; Arythmol; 1-Propanone, 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-, hydrochloride (1:1); EINECS 251-867-9; 1-{2-[2-Hydroxy-3-(propylamino) |
| Molecular Formula | C21H28ClNO3 |
| Molecular Weight | 377.90 |
| Purity | 98 |
| Boiling Point | 519.6ºC at 760 mmHg |
| Melting Point | 165-1670C |
| Appearance | white solid |
| Water Solubility | Water solubility: virtually insoluble; soluble in: |
| Storage Condition | Sealed, stored at 2ºC -8ºC |
| Application | Propafenone hydrochloride is an antiarrhythmic compound that acts on atrial and ventricular arrhythmias. |
| HTC | 2932999099 |
| PubChem ID | 329750974 |
| MDL Number | MFCD00079243 |
| SMILES | Cl[H].CCCNCC(O)COc1ccccc1C(=O)CCc2ccccc2 |
| InChI | 1S/C21H27NO3.ClH/c1-2-14-22-15-18(23)16-25-21-11-7-6-10-19(21)20(24)13-12-17-8-4-3-5-9-17;/h3-11,18,22-23H,2,12-16H2,1H3;1H |
| InChI Key | XWIHRGFIPXWGEF-UHFFFAOYSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/12152_1_34183_22_7.pdf |
| Bioactivity | Propafenone Hydrochloride is a class of anti-arrhythmic medication, which treats illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias.Target: Sodium ChannelPropafenone Hydrochloride is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial and ventricular arrhythmias. According to the Allergic Rhinitis and its Impact on Asthma (ARIA) treatment guidelines, intranasal anti-histamines are recommended for the first line therapy of mild intermittent, moderate/severe intermittent and mild persistent rhinitis (new classification system for rhinitis). Propafenone works by slowing the influx of sodium ions into the cardiac muscle cells, causing a decrease in excitability of the cells. Propafenone is more selective for cells with a high rate, but also blocks normal cells more than class Ia or Ib. Propafenone differs from the prototypical class Ic antiarrhythmic in that it has additional activity as a beta-adrenergic blocker which can cause bradycardia and bronchospasm . Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Cardiovascular Disease References [1]. http://en.wikipedia.org/wiki/Propafenone Chemical & Physical Properties Boiling Point 519.6ºC at 760 mmHg Melting Point 165-1670C Molecular Formula C21H28ClNO3 Molecular Weight 377.905 Flash Point 268ºC Exact Mass 377.175781 PSA 58.56000 LogP 4.43430 InChIKey XWIHRGFIPXWGEF-UHFFFAOYSA-N SMILES CCCNCC(O)COc1ccccc1C(=O)CCc1ccccc1.Cl Storage condition 2-8°C |
| Use of | Propafenone Hydrochloride is a class of anti-arrhythmic medication, which treats illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias.Target: Sodium ChannelPropafenone Hydrochloride is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial and ventricular arrhythmias. According to the Allergic Rhinitis and its Impact on Asthma (ARIA) treatment guidelines, intranasal anti-histamines are recommended for the first line therapy of mild intermittent, moderate/severe intermittent and mild persistent rhinitis (new classification system for rhinitis). Propafenone works by slowing the influx of sodium ions into the cardiac muscle cells, causing a decrease in excitability of the cells. Propafenone is more selective for cells with a high rate, but also blocks normal cells more than class Ia or Ib. Propafenone differs from the prototypical class Ic antiarrhythmic in that it has additional activity as a beta-adrenergic blocker which can cause bradycardia and bronchospasm . Properties Articles39 Name propafenone hydrochloride Synonym More Synonyms Propafenone hydrochloride Biological Activity Description Propafenone Hydrochloride is a class of anti-arrhythmic medication, which treats illnesses associated with rapid heart beats such as atrial and ventricular arrhythmias.Target: Sodium ChannelPropafenone Hydrochloride is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial and ventricular arrhythmias. According to the Allergic Rhinitis and its Impact on Asthma (ARIA) treatment guidelines, intranasal anti-histamines are recommended for the first line therapy of mild intermittent, moderate/severe intermittent and mild persistent rhinitis (new classification system for rhinitis). Propafenone works by slowing the influx of sodium ions into the cardiac muscle cells, causing a decrease in excitability of the cells. Propafenone is more selective for cells with a high rate, but also blocks normal cells more than class Ia or Ib. Propafenone differs from the prototypical class Ic antiarrhythmic in that it has additional activity as a beta-adrenergic blocker which can cause bradycardia and bronchospasm . Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Cardiovascular Disease References [1]. http://en.wikipedia.org/wiki/Propafenone Chemical & Physical Properties Exact Mass 377.175781 PSA 58.56000 LogP 4.43430 InChIKey XWIHRGFIPXWGEF-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
| Inspection | R. Hygiene supervision and inspection of imported food S. Hygiene supervision and inspection of exported food |
| Transport Info | Product name: Supervision conditions A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| Prometryn | 7287-19-6 | 2A-9012147 |
| Pronetalol | 54-80-8 | 2A-9012148 |
| Propacetamol | 66532-85-2 | 2A-9012149 |
| Propacetamol hydrochloride | 66532-86-3 | 2A-9012150 |
| Propafenone | 54063-53-5 | 2A-9012151 |
| Propamocarb | 24579-73-5 | 2A-9012153 |
| Propanil | 709-98-8 | 2A-9012154 |
| Propantheline bromide | 50-34-0 | 2A-9012155 |
| Propaquizafop | 111479-05-1 | 2A-9012156 |
| Proparacaine | 298-50-0 | 2A-9012157 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS