CAS Number54110-25-7
Synonyms2,6-Pyridinediyldimethylene bis(3,4,5-trimethoxybenzoate); 2,6-Pyridinediylbis(methylene) 3,4,5-trimethoxybenzoate; Benzoic acid,3,4,5-trimethoxy-,2,6-pyridinediylbis(methylene) ester; EINECS 258-978-1; Pirozadil; 722 d; Pirozadilum [INN-Latin]; Pemix; 2,6-Pyridinedimethanol bis(3,4,5-trimethoxybenzoate)
Molecular FormulaC27H29NO10
Molecular Weight527.52000
Purity98.00%
Density1.244g/cm3
Boiling Point594ºC at 760mmHg
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 54110-25-7 |
| Catalog No. | 2A-9012053 |
| Chinese Name | 吡扎地尔 |
| Synonyms | 2,6-Pyridinediyldimethylene bis(3,4,5-trimethoxybenzoate); 2,6-Pyridinediylbis(methylene) 3,4,5-trimethoxybenzoate; Benzoic acid,3,4,5-trimethoxy-,2,6-pyridinediylbis(methylene) ester; EINECS 258-978-1; Pirozadil; 722 d; Pirozadilum [INN-Latin]; Pemix; 2,6-Pyridinedimethanol bis(3,4,5-trimethoxybenzoate) |
| Molecular Formula | C27H29NO10 |
| Molecular Weight | 527.52000 |
| Purity | 98.00 |
| Density | 1.244g/cm3 |
| Boiling Point | 594ºC at 760mmHg |
| Storage Condition | 2-8℃ |
| Application | Pirozadil is a lipid-lowering drug. |
| HTC | 2933399090 |
| SMILES | COc1cc(C(=O)OCc2cccc(COC(=O)c3cc(OC)c(OC)c(OC)c3)n2)cc(OC)c1OC |
| InChI | InChI=1S/C27H29NO10/c1-31-20-10-16(11-21(32-2)24(20)35-5)26(29)37-14-18-8-7-9-19(28-18)15-38-27(30)17-12-22(33-3)25(36-6)23(13-17)34-4/h7-13H,14-15H2,1-6H3 |
| InChI Key | DIIBXMIIOQXTHW-UHFFFAOYSA-N |
| Use of | Pirozadil is a hypolipidemic agent. Properties Name [6-[(3,4,5-trimethoxybenzoyl)oxymethyl]pyridin-2-yl]methyl 3,4,5-trimethoxybenzoate Synonym More Synonyms Pirozadil Biological Activity Description Pirozadil is a hypolipidemic agent. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease In Vivo Pirozadil is a hypolipidemic agent. Pirozadil's effect on increasing cerebral blood flow is almost equal to that of papaverine, less than that of nicardipine and much greater than that of the other hypolipidemic/antiatherogenic drugs, nicotinic acid and pyridinol carbamate. Pirozadil is also shown to significantly diminish vascular cerebral resistance to a much greater degree than nicotinic acid and pyridinol carbamate[1]. References [1]. Roca J, et al. Effect of pirozadil on cerebral blood flow in anesthetized dogs. Methods Find Exp Clin Pharmacol. 1981 Nov-Dec;3(6):397-401. Chemical & Physical Properties Molecular Formula C27H29NO10 Exact Mass 527.17900 PSA 120.87000 LogP 3.84720 Index of Refraction 1.559 InChIKey DIIBXMIIOQXTHW-UHFFFAOYSA-N Storage condition 2-8℃ Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CHEMICAL NAME : Benzoic acid, 3,4,5-trimethoxy-, 2,6-pyridinediylbis(methylene) ester CAS REGISTRY NUMBER : 54110-25-7 LAST UPDATED : DATA ITEMS CITED : MOLECULAR FORMULA : C27-H29-N-O10 MOLECULAR WEIGHT : HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AFTOD7 Archivos de Farmacologia y Toxicologia. (Universidad Complutense, Facultad de Medicina, Departamento Coordinado de Farmacologia, Ciudad Universitaria, Madrid 3, Spain) V.1- 1975- Volume(issue)/page/year: 6,41,1980 Safety Information HS Code 2933399090 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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