CAS Number2277-92-1
Synonyms2,3,5-Trichlor-N-(3,5-dichlor-2-hydroxyphenyl)-6-hydroxybenzolcarboxamid; MFCD00864507; Zanilox; Oxyclozanide; diplin; 3,3',5,5',6-Pentachloro-2'-hydroxysalicylanilid; EINECS 218-904-0; OXYCLOZAMIDE; Oxycloxanide; zanil; Saucylanilide; 3,3',5,5',6-pentachloro-2'-hydroxysalicylanilide; 2,3,5-Trichloro-N-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxybenzamide; oxyclozanid
Molecular FormulaC13H6Cl5NO3
Molecular Weight401.46
Purity98%
Density1.8±0.1 g/cm3
Boiling Point446.0±45.0 °C at 760 mmHg
Melting Point205 - 210ºC
Appearancesolid
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 2277-92-1 |
| Catalog No. | 2A-0202371 |
| Chinese Name | 五氯柳胺 |
| Synonyms | 2,3,5-Trichlor-N-(3,5-dichlor-2-hydroxyphenyl)-6-hydroxybenzolcarboxamid; MFCD00864507; Zanilox; Oxyclozanide; diplin; 3,3',5,5',6-Pentachloro-2'-hydroxysalicylanilid; EINECS 218-904-0; OXYCLOZAMIDE; Oxycloxanide; zanil; Saucylanilide; 3,3',5,5',6-pentachloro-2'-hydroxysalicylanilide; 2,3,5-Trichloro-N-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxybenzamide; oxyclozanid |
| Molecular Formula | C13H6Cl5NO3 |
| Molecular Weight | 401.46 |
| Purity | 98 |
| Density | 1.8±0.1 g/cm3 |
| Boiling Point | 446.0±45.0 °C at 760 mmHg |
| Melting Point | 205 - 210ºC |
| Appearance | solid |
| Storage Condition | Store at 0-6°C |
| Application | Oxyclozanide is a salicylanilide anthelmintic that works primarily by uncoupling oxidative phosphorylation in flukes. |
| HTC | 2924299090 |
| MDL Number | MFCD00864507 |
| SMILES | Oc1c(Cl)cc(Cl)cc1NC(=O)c2c(O)c(Cl)cc(Cl)c2Cl |
| InChI | 1S/C13H6Cl5NO3/c14-4-1-6(16)11(20)8(2-4)19-13(22)9-10(18)5(15)3-7(17)12(9)21/h1-3,20-21H,(H,19,22) |
| InChI Key | JYWIYHUXVMAGLG-UHFFFAOYSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| MSDS | msds/11835_1_2277_92_1.pdf |
| Use of | Oxyclozanide is a salicylanilide anthelmintic drug that mainly acts by uncoupling oxidative phosphorylation in flukes. Properties Articles27 Name Oxyclozanide Synonym More Synonyms Oxyclozanide Biological Activity Description Oxyclozanide is a salicylanilide anthelmintic drug that mainly acts by uncoupling oxidative phosphorylation in flukes. Related Catalog Signaling Pathways >> Anti-infection >> Parasite Research Areas >> Infection Parasite[1] References [1]. Gokbulut C, et al. Comparative pharmacokinetics of levamisole-oxyclozanide combination in sheep and goats following per os administration. Can J Vet Res. 2014 Oct;78(4):316-20. Chemical & Physical Properties Exact Mass 398.879028 PSA 69.56000 Index of Refraction 1.722 InChIKey JYWIYHUXVMAGLG-UHFFFAOYSA-N Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CHEMICAL NAME : Benzanilide, 2,2'-dihydroxy-3,3',5,5',6-pentachloro- CAS REGISTRY NUMBER : LAST UPDATED : DATA ITEMS CITED : MOLECULAR FORMULA : C13-H6-Cl5-N-O3 MOLECULAR WEIGHT : WISWESSER LINE NOTATION : QR BG DG FMVR BQ CG EG FG HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869- Volume(issue)/page/year: 210,744,1966 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : SPECIES OBSERVED : Mammal - domestic DOSE/DURATION : TOXIC EFFECTS : Behavioral - muscle weakness Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain REFERENCE : VETRAX Veterinary Record. (7 Mansfield St., London W1M 0AT, UK) V.1- 1888- Volume(issue)/page/year: 78,267,1966 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : SPECIES OBSERVED : Mammal - cattle DOSE/DURATION : TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Behavioral - coma Lungs, Thorax, or Respiration - respiratory stimulation REFERENCE : VETRAX Veterinary Record. (7 Mansfield St., London W1M 0AT, UK) V.1- 1888- Volume(issue)/page/year: 78,267,1966 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - domestic DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : VETRAX Veterinary Record. (7 Mansfield St., London W1M 0AT, UK) V.1- 1888- Volume(issue)/page/year: 78,267,1966 Safety Information GHS07, GHS09 Signal Word Warning Hazard Statements H302-H410 Precautionary Statements P273-P501 Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves Hazard Codes Xn:Harmful;N:Dangerousfortheenvironment; Safety Phrases S60-S61 RIDADR UN 3077 RTECS CV8576000 HS Code 2924299090 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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