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2-AMINO-3-(3-HYDROXY-5-METHYLISOXAZOL-4-YL)PROPANOIC ACID HYDROBROMIDE structure, CAS 171259-81-7

2-AMINO-3-(3-HYDROXY-5-METHYLISOXAZOL-4-YL)PROPANOIC ACID HYDROBROMIDE

CAS Number171259-81-7

Synonyms3-(3-Hydroxy-5-methyl-1,2-oxazol-4-yl)alanine hydrobromide (1:1)

Molecular FormulaC7H11BrN2O4

Molecular Weight267.08

Purity96+%

Density

Boiling Point

Melting Point205-208°C

Flash Point

Appearance

EINECS0

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Cat. No.: 2A-0118054 Purity: 96+%
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Quality Control of [ 171259-81-7 ] Purity: 96+% SDS Specification MoL

Chemical & Physical Properties
CAS Number171259-81-7
Catalog No.2A-0118054
Chinese Name(R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid HydrobromideSee: A611500
Synonyms3-(3-Hydroxy-5-methyl-1,2-oxazol-4-yl)alanine hydrobromide (1:1)
Molecular FormulaC7H11BrN2O4
Molecular Weight267.08
Purity96+
Melting Point205-208°C
Storage Condition2-8°C, sealed, dry
Application(RS)-AMPA ((±)-AMPA) hydrobromide is a glutamate analogue and a potent and selective agonist of the excitatory neurotransmitter L-glutamic acid. (RS)-AMPA hydrobromide does not interfere with alginate
EINECS0
HTC2934999090
UN(IATA)0
PubChem ID329771033
MDL NumberMFCD00055183
SMILESBr.Cc1o[nH]c(=O)c1CC(N)C(=O)O
InChIInChI=1S/C7H10N2O4.BrH/c1-3-4(6(10)9-13-3)2-5(8)7(11)12;/h5H,2,8H2,1H3,(H,9,10)(H,11,12);1H
InChI KeyKUAHVIUZGLGASU-UHFFFAOYSA-N
NACRES CodeNA.77
UNSPSC12352200
Use of(RS)-AMPA ((±)-AMPA) hydrobromide is a glutamate analogue and a potent and selective excitatory neurotransmitter L-glutamic acid agonist. (RS)-AMPA hydrobromide does not interfere with binding sites for kainic acid or NMDA receptors[1][2]. Properties Name (R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Hydrobromide Synonym More Synonyms Biological Activity Description (RS)-AMPA ((±)-AMPA) hydrobromide is a glutamate analogue and a potent and selective excitatory neurotransmitter L-glutamic acid agonist. (RS)-AMPA hydrobromide does not interfere with binding sites for kainic acid or NMDA receptors[1][2]. Related Catalog Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR References [1]. Hösli L, et al. Effects of the glutamate analogue AMPA and its interaction with antagonists on cultured rat spinal and brain stem neurones. Neurosci Lett. 1983 Mar 28;36(1):59-62. [2]. Sommer B, et al. Flip and flop: a cell-specific functional switch in glutamate-operated channels of the CNS. Science. 1990 Sep 28;249(4976):1580-5. Chemical & Physical Properties Molecular Formula C7H11BrN2O4 Exact Mass 265.99000 PSA 109.58000 LogP 1.30140 InChIKey KUAHVIUZGLGASU-UHFFFAOYSA-N Safety Information RIDADR NONH for all modes of transport HS Code 2934999090 Synthetic Route diethyl acetami... CAS#:75989-23-0 (R,S)-α-Amino-3... CAS#:171259-81-7 Literature: Hanson, Robert N.; Mohamed, Fand A. Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 1 p. 345 - 348 3-methoxy-4-hyd... CAS#:75989-21-8 (R,S)-α-Amino-3... CAS#:171259-81-7 Literature: Hansen; Krogsgaard-Larsen Journal of the Chemical Society. Perkin transactions 1, 1980 , vol. 8, p. 1826 - 1833 Isoxazole, 4-(c... CAS#:75989-22-9 (R,S)-α-Amino-3... CAS#:171259-81-7 Literature: Hansen; Krogsgaard-Larsen Journal of the Chemical Society. Perkin transactions 1, 1980 , vol. 8, p. 1826 - 1833 Precursor & DownStream Precursor 7 CAS#:75989-23-0 diethyl acetami... CAS#:75989-21-8 3-methoxy-4-hyd... CAS#:75989-22-9 Isoxazole, 4-(c... CAS#:16877-56-8 4-Isoxazolecarb... DownStream 0
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