
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 171259-81-7 |
| Catalog No. | 2A-0118054 |
| Chinese Name | (R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid HydrobromideSee: A611500 |
| Synonyms | 3-(3-Hydroxy-5-methyl-1,2-oxazol-4-yl)alanine hydrobromide (1:1) |
| Molecular Formula | C7H11BrN2O4 |
| Molecular Weight | 267.08 |
| Purity | 96+ |
| Melting Point | 205-208°C |
| Storage Condition | 2-8°C, sealed, dry |
| Application | (RS)-AMPA ((±)-AMPA) hydrobromide is a glutamate analogue and a potent and selective agonist of the excitatory neurotransmitter L-glutamic acid. (RS)-AMPA hydrobromide does not interfere with alginate |
| EINECS | 0 |
| HTC | 2934999090 |
| UN(IATA) | 0 |
| PubChem ID | 329771033 |
| MDL Number | MFCD00055183 |
| SMILES | Br.Cc1o[nH]c(=O)c1CC(N)C(=O)O |
| InChI | InChI=1S/C7H10N2O4.BrH/c1-3-4(6(10)9-13-3)2-5(8)7(11)12;/h5H,2,8H2,1H3,(H,9,10)(H,11,12);1H |
| InChI Key | KUAHVIUZGLGASU-UHFFFAOYSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| Use of | (RS)-AMPA ((±)-AMPA) hydrobromide is a glutamate analogue and a potent and selective excitatory neurotransmitter L-glutamic acid agonist. (RS)-AMPA hydrobromide does not interfere with binding sites for kainic acid or NMDA receptors[1][2]. Properties Name (R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Hydrobromide Synonym More Synonyms Biological Activity Description (RS)-AMPA ((±)-AMPA) hydrobromide is a glutamate analogue and a potent and selective excitatory neurotransmitter L-glutamic acid agonist. (RS)-AMPA hydrobromide does not interfere with binding sites for kainic acid or NMDA receptors[1][2]. Related Catalog Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR References [1]. Hösli L, et al. Effects of the glutamate analogue AMPA and its interaction with antagonists on cultured rat spinal and brain stem neurones. Neurosci Lett. 1983 Mar 28;36(1):59-62. [2]. Sommer B, et al. Flip and flop: a cell-specific functional switch in glutamate-operated channels of the CNS. Science. 1990 Sep 28;249(4976):1580-5. Chemical & Physical Properties Molecular Formula C7H11BrN2O4 Exact Mass 265.99000 PSA 109.58000 LogP 1.30140 InChIKey KUAHVIUZGLGASU-UHFFFAOYSA-N Safety Information RIDADR NONH for all modes of transport HS Code 2934999090 Synthetic Route diethyl acetami... CAS#:75989-23-0 (R,S)-α-Amino-3... CAS#:171259-81-7 Literature: Hanson, Robert N.; Mohamed, Fand A. Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 1 p. 345 - 348 3-methoxy-4-hyd... CAS#:75989-21-8 (R,S)-α-Amino-3... CAS#:171259-81-7 Literature: Hansen; Krogsgaard-Larsen Journal of the Chemical Society. Perkin transactions 1, 1980 , vol. 8, p. 1826 - 1833 Isoxazole, 4-(c... CAS#:75989-22-9 (R,S)-α-Amino-3... CAS#:171259-81-7 Literature: Hansen; Krogsgaard-Larsen Journal of the Chemical Society. Perkin transactions 1, 1980 , vol. 8, p. 1826 - 1833 Precursor & DownStream Precursor 7 CAS#:75989-23-0 diethyl acetami... CAS#:75989-21-8 3-methoxy-4-hyd... CAS#:75989-22-9 Isoxazole, 4-(c... CAS#:16877-56-8 4-Isoxazolecarb... DownStream 0 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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