CAS Number13297-17-1
Synonyms2-methyl-3-acetyl-quinoxaline 1,4-dioxide; 2-acetyl-3-methylquinoxalinediium-1,4-diolate; 1-(3-methyl-1,4-dioxidoquinoxalin-2-yl)ethanone; 2-acetyl-3-methylquinoxaline 1,4-di-N-oxide; 2-methylcarbonyl-3-methyl-1,4-dioxoquinoxaline; 2-Acetyl-3-methylquinoxaline 1,4-dioxide; 3-methyl-2-acetylquinoxaline-1,4-dioxide; 1-(3-Methyl-1,4-dioxido-2-quinoxalinyl)ethanone
Molecular FormulaC11H10O3N2
Molecular Weight218.21
Purity96+%
Density1.3±0.1 g/cm3
Boiling Point457.3±55.0 °C at 760 mmHg
Appearancepowder
EINECS0
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 13297-17-1 |
| Catalog No. | 2A-0117610 |
| Chinese Name | 乙酰甲喹 |
| Synonyms | 2-methyl-3-acetyl-quinoxaline 1,4-dioxide; 2-acetyl-3-methylquinoxalinediium-1,4-diolate; 1-(3-methyl-1,4-dioxidoquinoxalin-2-yl)ethanone; 2-acetyl-3-methylquinoxaline 1,4-di-N-oxide; 2-methylcarbonyl-3-methyl-1,4-dioxoquinoxaline; 2-Acetyl-3-methylquinoxaline 1,4-dioxide; 3-methyl-2-acetylquinoxaline-1,4-dioxide; 1-(3-Methyl-1,4-dioxido-2-quinoxalinyl)ethanone |
| Molecular Formula | C11H10O3N2 |
| Molecular Weight | 218.21 |
| Purity | 96+ |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 457.3±55.0 °C at 760 mmHg |
| Appearance | powder |
| Storage Condition | room temperature |
| Application | Mequindox is an antibacterial agent. Mequindox is an inhibitor of DNA synthesis. Mequindox is genotoxic and carcinogenic in mice. |
| EINECS | 0 |
| HTC | 2933990090 |
| UN(IATA) | 0 |
| PubChem ID | 535532 |
| MDL Number | MFCD00113235 |
| SMILES | CC(=O)c1c(C)n([O-])c2ccccc2[n+]1=O |
| InChI | InChI=1S/C11H10N2O3/c1-7-11(8(2)14)13(16)10-6-4-3-5-9(10)12(7)15/h3-6H,1-2H3 |
| InChI Key | CUJMCPPBTUATEJ-UHFFFAOYSA-N |
| Use of | Mequindox is an antimicrobial agent[1]. Mequindox acts as an inhibitor of DNA synthesis. Mequindox induces genotoxicity and carcinogenicity in mice[2]. Properties Name 1-(3-methyl-4-oxido-1-oxoquinoxalin-1-ium-2-yl)ethanone Synonym More Synonyms Mequindox Biological Activity Description Mequindox is an antimicrobial agent[1]. Mequindox acts as an inhibitor of DNA synthesis. Mequindox induces genotoxicity and carcinogenicity in mice[2]. Related Catalog Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis Signaling Pathways >> Anti-infection >> Bacterial References [1]. Qianying Liu, et al. Mequindox-Induced Kidney Toxicity Is Associated With Oxidative Stress and Apoptosis in the Mouse. Front Pharmacol. 2018 May 1;9:436. [2]. Qianying Liu, et al. Mequindox Induced Genotoxicity and Carcinogenicity in Mice. Front Pharmacol. 2018 Apr 10;9:361. Chemical & Physical Properties Molecular Formula C11H10N2O3 Exact Mass 218.069138 PSA 67.99000 LogP -0.90 Index of Refraction 1.627 InChIKey CUJMCPPBTUATEJ-UHFFFAOYSA-N Safety Information HS Code 2933990090 Synthetic Route Benzofuroxan CAS#:480-96-6 2,4-Pentandione CAS#:123-54-6 CAS#:13297-17-1 Literature: El-Halim, M. S. Abd; El-Ahl, A. S.; Etman, H. A.; Ali, M. M.; Fouda, A.; Fadda, A. A. Monatshefte fuer Chemie, 1995 , vol. 126, # 11 p. 1217 - 1224 2-Nitroaniline CAS#:88-74-4 CAS#:13297-17-1 Literature: Synthetic Communications, , vol. 41, # 20 p. 3097 - 3105 CAS#:1322877-87-1 2,4-Pentandione CAS#:123-54-6 CAS#:13297-17-1 Literature: Synthetic Communications, , vol. 41, # 20 p. 3097 - 3105 Precursor & DownStream Precursor 5 CAS#:480-96-6 Benzofuroxan CAS#:123-54-6 2,4-Pentandione CAS#:88-74-4 2-Nitroaniline CAS#:1322877-87-1 DownStream 6 CAS#:81810-66-4 Deciquam Solution CAS#:22059-64-9 1-(3-Methylquin... CAS#:61522-56-3 1-(3-methyl-4-o... CAS#:61522-57-4 4-desoxy-mequindox |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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