![2-[(4-BROMOPHENYL)PHENYLMETHOXY]-N,N-DIMETHYLETHANAMINE structure, CAS 118-23-0](/structures/120000/117419_1_118_23_0.png)
CAS Number118-23-0
SynonymsHistabromamine; N-2-(4-bromobenzhydryloxy)ethyldimethylamine; EINECS 204-238-8; bromodiphenhydramine; Bromanautine; Bromo-Benadryl; Ethanamine,2-(4-bromophenyl)phenylmethoxy-N,N-dimethyl
Molecular FormulaC17H20BrNO
Molecular Weight370.71
Purity96+%
Density1.259g/cm3
Boiling Point397.3ºC at 760mmHg
EINECS0
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 118-23-0 |
| Catalog No. | 2A-0117419 |
| Chinese Name | 溴苯海明 |
| Synonyms | Histabromamine; N-2-(4-bromobenzhydryloxy)ethyldimethylamine; EINECS 204-238-8; bromodiphenhydramine; Bromanautine; Bromo-Benadryl; Ethanamine,2-(4-bromophenyl)phenylmethoxy-N,N-dimethyl |
| Molecular Formula | C17H20BrNO |
| Molecular Weight | 370.71 |
| Purity | 96+ |
| Density | 1.259g/cm3 |
| Boiling Point | 397.3ºC at 760mmHg |
| Application | Ambodryl is a powerful antihistamine with antibacterial properties. Bromide inhibits a wide range of Gram-negative and Gram-positive bacteria. Bromodiphenylhydrazine can be used in skin allergy resear |
| EINECS | 0 |
| HTC | 2922199090 |
| UN(IATA) | 0 |
| PubChem ID | 329749133 |
| MDL Number | MFCD01727165 |
| SMILES | CN(C)CCOC(c1ccccc1)c1ccc(Br)cc1 |
| InChI | InChI=1S/C17H20BrNO.ClH/c1-19(2)12-13-20-17(14-6-4-3-5-7-14)15-8-10-16(18)11-9-15;/h3-11,17H,12-13H2,1-2H3;1H |
| InChI Key | NUNIWXHYABYXKF-UHFFFAOYSA-N |
| Beilstein/REAXYS | 3754363 |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| Use of | Bromodiphenhydramine (Ambodryl) is a potent antihistamine with antimicrobial property. Bromodiphenhydramine inhibits a large number of Gram negative and Gram positive bacteria. Bromodiphenhydramine can be used for cutaneous allergies research[1][2][3]. Properties Name bromazine Synonym More Synonyms bromazine Biological Activity Description Bromodiphenhydramine (Ambodryl) is a potent antihistamine with antimicrobial property. Bromodiphenhydramine inhibits a large number of Gram negative and Gram positive bacteria. Bromodiphenhydramine can be used for cutaneous allergies research[1][2][3]. Related Catalog Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Infection Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Histamine Receptor Signaling Pathways >> Anti-infection >> Bacterial In Vivo Bromodiphenhydramine (1.5 and 3 μg/g, single) protects mice against a challenge with a virulent strain of Salmonella typhimurium, and also significantly reduces the multiplication of this organism in the liver, spleen and blood of the protected animals in comparison with the unprotected controls[2]. References [1]. MOLINA EB. [A new antihistaminic, bromodiphenhydramine hydrochloride, in the control of cutaneous allergies]. Sem Med. 1960 Jul 11;117:151-2. Spanish. [2]. Dastidar SG, et al. Antibacterial activity of ambodryl and benadryl. J Appl Bacteriol. 1976 Oct;41(2):209-14. [3]. Ray S, et al. Studies on synergism between penicillins and ambodryl (bromodiphenhydramine HCl), an antihistamine with antimicrobial property. Indian J Exp Biol. 1990 Mar;28(3):253-8. Chemical & Physical Properties Molecular Formula C17H20BrNO Exact Mass 333.07300 PSA 12.47000 LogP 4.11670 InChIKey NUNIWXHYABYXKF-UHFFFAOYSA-N Safety Information HS Code 2922199090 Precursor & DownStream Precursor 0 DownStream 1 CAS#:1808-12-4 Bromodiphenhydr... |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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