CAS Number35189-28-7
Synonyms(+)-13-Ethyl-17-hydroxy-18,19-dinor-17a-pregn-4-en-20-yn-3-one Oxime Acetate (Ester); d-17beta-acetoxy-13beta-ethyl-17alpha-ethinyl-gon-4en-3-one oxime; dexnorgestrelacetime; Norgestimat; Norgestimate; NORGESTIMATE,USP STANDARD; levonorgestrel acetate 3-oxime
Molecular FormulaC23H31NO3
Molecular Weight354.48
Purity98%
Density1.2±0.1 g/cm3
Boiling Point497.9±45.0 °C at 760 mmHg
Melting Point216ºC
AppearanceWhite crystalline solid
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 35189-28-7 |
| Catalog No. | 2A-9011713 |
| Chinese Name | 炔诺肟酯 |
| Synonyms | (+)-13-Ethyl-17-hydroxy-18,19-dinor-17a-pregn-4-en-20-yn-3-one Oxime Acetate (Ester); d-17beta-acetoxy-13beta-ethyl-17alpha-ethinyl-gon-4en-3-one oxime; dexnorgestrelacetime; Norgestimat; Norgestimate; NORGESTIMATE,USP STANDARD; levonorgestrel acetate 3-oxime |
| Molecular Formula | C23H31NO3 |
| Molecular Weight | 354.48 |
| Purity | 98 |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 497.9±45.0 °C at 760 mmHg |
| Melting Point | 216ºC |
| Appearance | White crystalline solid |
| Application | Norgestimate is a synthetic progestin analog, an orally active progestin with highly selective progestogenic activity and minimal androgenic effects. Norgestimate is available for oral contraceptives. |
| MDL Number | MFCD11978024 |
| SMILES | C#CC1(OC(C)=O)CCC2C3CCC4=CC(=NO)CCC4C3CCC21CC |
| InChI Key | KIQQMECNKUGGKA-OMEWWMGKSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| Hazard Symbols | Transport |
| MSDS | msds/11713_1_35189_28_7.pdf |
| Bioactivity | Norgestimate, a synthetic progesterone analog, is an orally active progestin with highly selective progestational activity and minimal androgenicity. Norgestimate is used for an oral contraceptive[1][2]. Related Catalog Signaling Pathways >> Others >> Progesterone Receptor Research Areas >> Endocrinology In Vitro Norgestimate is converted to at least two active metabolites: levonorgestrel 3-oxime (deacetylated norgestimate; norelgestromin) and levonorgestrel[1]. References [1]. Stanczyk FZ, et al. All progestins are not created equal. Steroids. 2003 Nov;68(10-13):879-90. [2]. Phillips A, et al. Preclinical evaluation of norgestimate, a progestin with minimal androgenic activity. Am J Obstet Gynecol. 1992 Oct;167(4 Pt 2):1191-6. Chemical & Physical Properties Density 1.2±0.1 g/cm3 Boiling Point 497.9±45.0 °C at 760 mmHg Melting Point 216ºC Molecular Formula C23H31NO3 Molecular Weight 369.497 Flash Point 254.9±28.7 °C Exact Mass 369.230408 PSA 58.89000 LogP 5.00 Vapour Pressure 0.0±2.9 mmHg at 25°C Index of Refraction 1.611 InChIKey KIQQMECNKUGGKA-OMEWWMGKSA-N SMILES C#CC1(OC(C)=O)CCC2C3CCC4=CC(=NO)CCC4C3CCC21CC |
| Use of | Norgestimate, a synthetic progesterone analog, is an orally active progestin with highly selective progestational activity and minimal androgenicity. Norgestimate is used for an oral contraceptive[1][2]. Properties Articles42 Name norgestimate Synonym More Synonyms Norgestimate Biological Activity Description Norgestimate, a synthetic progesterone analog, is an orally active progestin with highly selective progestational activity and minimal androgenicity. Norgestimate is used for an oral contraceptive[1][2]. Related Catalog Signaling Pathways >> Others >> Progesterone Receptor Research Areas >> Endocrinology In Vitro Norgestimate is converted to at least two active metabolites: levonorgestrel 3-oxime (deacetylated norgestimate; norelgestromin) and levonorgestrel[1]. References [1]. Stanczyk FZ, et al. All progestins are not created equal. Steroids. 2003 Nov;68(10-13):879-90. [2]. Phillips A, et al. Preclinical evaluation of norgestimate, a progestin with minimal androgenic activity. Am J Obstet Gynecol. 1992 Oct;167(4 Pt 2):1191-6. Chemical & Physical Properties Molecular Formula C23H31NO3 Exact Mass 369.230408 PSA 58.89000 Index of Refraction 1.611 InChIKey KIQQMECNKUGGKA-OMEWWMGKSA-N |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available The above information is believed to be correct, but is not all-inclusive and should be used as a guide only. The information in this document is based on our current knowledge and is Correct safety instructions apply to this product. This information does not represent a warranty as to the properties of this product. See reverse side of invoice or packing slip. |
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