CAS Number16915-70-1
SynonymsMFCD00377430; Salfuride; NIFURSOL; Nifursolum [INN-Latin]; Histomon; EINECS 240-963-6; Nifursolo [DCIT]; Sulfuride
Molecular FormulaC12H7N5O9
Molecular Weight365.21200
Purity98%
Density1.87 g/cm3
Melting Point215-220ºC (dec.)
AppearanceFresh yellow crystal or yellow powder, odorless
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 16915-70-1 |
| Catalog No. | 2A-9011662 |
| Chinese Name | 尼呋索尔 |
| Synonyms | MFCD00377430; Salfuride; NIFURSOL; Nifursolum [INN-Latin]; Histomon; EINECS 240-963-6; Nifursolo [DCIT]; Sulfuride |
| Molecular Formula | C12H7N5O9 |
| Molecular Weight | 365.21200 |
| Purity | 98 |
| Density | 1.87 g/cm3 |
| Melting Point | 215-220ºC (dec.) |
| Appearance | Fresh yellow crystal or yellow powder, odorless |
| Storage Condition | Refrigerator, Under Inert Atmosphere |
| Application | Nifursol is a nitrofuran antibiotic. |
| HTC | 2942000000 |
| SMILES | O=C(NN=Cc1ccc([N+](=O)[O-])o1)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1O |
| InChI | InChI=1S/C12H7N5O9/c18-11-8(3-6(15(20)21)4-9(11)16(22)23)12(19)14-13-5-7-1-2-10(26-7)17(24)25/h1-5,18H,(H,14,19)/b13-5+ |
| InChI Key | XXUXXCZCUGIGPP-UHFFFAOYSA-N |
| Use of | Nifursol is a nitrofuran antibiotic which inhibits the growth of Histomonas meleagridis but is not lethal to the flagellated protozoan. Target: AntibacterialNifursol can be analyzed and detected in tissues using intact 3,5-dinitrosalicylic acid hydrazide side chains along with electron-capture GC, spectrophotometric detection, and HPLC with ultraviolet light detection. In tissues, it has been observed that Nifursol is tightly bound to proteins and requires basic solutions such as ammonia to break the bonds between the two. Properties Name 2-hydroxy-3,5-dinitro-N-[(E)-(5-nitrofuran-2-yl)methylideneamino]benzamide Synonym More Synonyms Nifursol Biological Activity Description Nifursol is a nitrofuran antibiotic which inhibits the growth of Histomonas meleagridis but is not lethal to the flagellated protozoan. Target: AntibacterialNifursol can be analyzed and detected in tissues using intact 3,5-dinitrosalicylic acid hydrazide side chains along with electron-capture GC, spectrophotometric detection, and HPLC with ultraviolet light detection. In tissues, it has been observed that Nifursol is tightly bound to proteins and requires basic solutions such as ammonia to break the bonds between the two. Related Catalog Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection Chemical & Physical Properties Molecular Formula C12H7N5O9 Exact Mass 365.02400 PSA 212.29000 LogP 3.43420 Index of Refraction 1.742 InChIKey XXUXXCZCUGIGPP-UHFFFAOYSA-N Storage condition Refrigerator, Under Inert Atmosphere Toxicological Information CHEMICAL IDENTIFICATION RTECS NUMBER : CHEMICAL NAME : Salicylic acid, 3,5-dinitro-(5-nitrofurfurylidene)hydrazide CAS REGISTRY NUMBER : 16915-70-1 LAST UPDATED : DATA ITEMS CITED : MOLECULAR FORMULA : C12-H7-N5-O9 MOLECULAR WEIGHT : WISWESSER LINE NOTATION : T5OJ BNW E1UNMVR BQ CNW ENW HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : SPECIES OBSERVED : Rodent - rat DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 12,371,1969 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : SPECIES OBSERVED : Bird - chicken DOSE/DURATION : TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 12,371,1969 Safety Information HS Code 2942000000 |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0% |
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