Home > Products > Pharmaceuticals & Life Science > Pharmaceutical Intermediates > 2-(FURAN-2-YL)-7-PHENETHYL-7H-PYRAZOLO[4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE

2-(FURAN-2-YL)-7-PHENETHYL-7H-PYRAZOLO[4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE

Name: 2-(FURAN-2-YL)-7-PHENETHYL-7H-PYRAZOLO[4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE
Brand: 2A Biotech
SKU: 2A-1116603

CAS Number160098-96-4

Synonyms7-(2-phenylethyl)-5-amino-2-(2-furyl)-pyrazolo-[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine; 2-(Furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine; SCH58261; SCH 58261

Molecular FormulaC18H15N7O

Molecular Weight345.36

Purity96+%

Density1.54g/cm3

EINECS0

MSDSChinese English

Cat. No.: 2A-1116603 Purity: 96+%

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Quality Control of [ 160098-96-4 ] Purity: 96+% SDS Specification MoL

Chemical & Physical Properties
CAS Number	160098-96-4
Catalog No.	2A-1116603
Chinese Name	2-(2-呋喃基)-7-(2-苯基乙基)-7H-吡唑并[4,3-e][1,2,4]噻唑并[1,5-c]嘧啶-5-胺
Synonyms	7-(2-phenylethyl)-5-amino-2-(2-furyl)-pyrazolo-[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine; 2-(Furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine; SCH58261; SCH 58261
Molecular Formula	C18H15N7O
Molecular Weight	345.36
Purity	96+
Density	1.54g/cm3
Storage Condition	2-8°C
Application	SCH58261 is a competitive antagonist of adenosine A2A receptor.
EINECS	0
HTC	2934999090
UN(IATA)	0
PubChem ID	329824547
MDL Number	MFCD00933778
SMILES	Nc1nc2c(cnn2CCc2ccccc2)c2nc(-c3ccco3)nn12
InChI	InChI=1S/C18H15N7O/c19-18-22-16-13(11-20-24(16)9-8-12-5-2-1-3-6-12)17-21-15(23-25(17)18)14-7-4-10-26-14/h1-7,10-11H,8-9H2,(H2,19,22)
InChI Key	UTLPKQYUXOEJIL-UHFFFAOYSA-N
NACRES Code	NA.77
UNSPSC	12352200
Use of	Properties Name 2-(2-furanyl)-7-(2-phenylethyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine Synonym More Synonyms SCH 58261 Biological Activity Related Catalog Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor Research Areas >> Cancer References [1]. Paul A. Beavis et al. Blockade of A2A receptors potently suppresses the metastasis of CD73+ tumors. Proc Natl Acad Sci U S A, 2013 Sep 3, 110(36): 14711-14716. [2]. Alessia Melani et al. Time-course of protection by the selective A2Areceptor antagonist SCH58261 after transient focal cerebral ischemia. Neurological Sciences, August 2015, Volume 36, Issue 8, pp 1441-1448. [3]. Varani K et al. Pharmacological and biochemical characterization of purified A2a adenosine receptors in human platelet membranes by [3H]-CGS 21680 binding. Br J Pharmacol, 1996 Apr;117(8):1693-701. Chemical & Physical Properties Molecular Formula C18H15N7O Exact Mass 345.13400 PSA 100.06000 LogP 3.14010 Index of Refraction 1.807 InChIKey UTLPKQYUXOEJIL-UHFFFAOYSA-N Safety Information Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter RIDADR NONH for all modes of transport HS Code 2934999090 Synthetic Route CAS#:420-04-2 5-amino-1-(β-ph... CAS#:159979-95-0 CAS#:160098-96-4 Literature: Baraldi, Pier Giovanni; Cacciari, Barbara; Spalluto, Giampiero; Pineda De Las Infantas Y Villatoro, Maria Jose; Zocchi, Cristina; Dionisotti, Silvio; Ongini, Ennio Journal of Medicinal Chemistry, 1996 , vol. 39, # 5 p. 1164 - 1171 2-Furoic acid h... CAS#:3326-71-4 CAS#:160098-96-4 Literature: Baraldi, Pier Giovanni; Cacciari, Barbara; Spalluto, Giampiero; Pineda De Las Infantas Y Villatoro, Maria Jose; Zocchi, Cristina; Dionisotti, Silvio; Ongini, Ennio Journal of Medicinal Chemistry, 1996 , vol. 39, # 5 p. 1164 - 1171 N-(4-imino-1-ph... CAS#:162401-28-7 CAS#:160098-96-4 Literature: Baraldi, Pier Giovanni; Cacciari, Barbara; Spalluto, Giampiero; Pineda De Las Infantas Y Villatoro, Maria Jose; Zocchi, Cristina; Dionisotti, Silvio; Ongini, Ennio Journal of Medicinal Chemistry, 1996 , vol. 39, # 5 p. 1164 - 1171 Precursor & DownStream Precursor 3 CAS#:420-04-2 CAS#:159979-95-0 5-amino-1-(β-ph... CAS#:3326-71-4 2-Furoic acid h... DownStream 0
Tax Rebate	13.0%
Supervision	None. MFN tariff: 6.5%. Ordinary tariff: 20.0%
Transport Info	Product name: Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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2-(FURAN-2-YL)-7-PHENETHYL-7H-PYRAZOLO[4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE

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