CAS Number134978-97-5
SynonymsAcetic acid,2-[2-(2-aminoethoxy)ethoxy]; (2-aminoethoxy)ethoxyacetic acid; 8-Amino-3,6-dioxaoctanoic acid; 2-(2-(2-Aminoethoxy)ethoxy)acetic acid; [2-(2-Aminoethoxy)ethoxy]acetic acid; [2-(N-2-amino ethoxy)ethoxy] acetic acid; ADOA; AEEA
Molecular FormulaC6H13O4N1
Molecular Weight163.17
Purity96+%
Density1.2±0.1 g/cm3
Boiling Point323.8±22.0 °C at 760 mmHg
Melting Point124.0 to 128.0 °C
AppearanceWhite-very light reddish-yellow crystal-powder
EINECS0
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 134978-97-5 |
| Catalog No. | 2A-1113680 |
| Chinese Name | 2-[2-(2-氨基乙氧基)乙氧基]乙酸 |
| Synonyms | Acetic acid,2-[2-(2-aminoethoxy)ethoxy]; (2-aminoethoxy)ethoxyacetic acid; 8-Amino-3,6-dioxaoctanoic acid; 2-(2-(2-Aminoethoxy)ethoxy)acetic acid; [2-(2-Aminoethoxy)ethoxy]acetic acid; [2-(N-2-amino ethoxy)ethoxy] acetic acid; ADOA; AEEA |
| Molecular Formula | C6H13O4N1 |
| Molecular Weight | 163.17 |
| Purity | 96+ |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 323.8±22.0 °C at 760 mmHg |
| Melting Point | 124.0 to 128.0 °C |
| Appearance | White-very light reddish-yellow crystal-powder |
| Storage Condition | -20°C |
| Application | H2N-PEG2-CH2COOH is a polyethylene glycol (PEG)-based linker. Covalently binds to the E3 ligase binding group (E3LB) and the target protein binding group (PB). |
| EINECS | 0 |
| HTC | 2922509090 |
| UN(IATA) | 0 |
| MDL Number | MFCD13185897 |
| SMILES | NCCOCCOCC(=O)O |
| InChI Key | RUVRGYVESPRHSZ-UHFFFAOYSA-N |
| Use of | Properties Name 2-[2-(2-aminoethoxy)ethoxy]acetic acid Synonym More Synonyms 8-amino-3,6-dioxaoctanoic acid Biological Activity Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker References [1]. Thomas Pillow, et al. Protac antibody conjugates and methods of use. WO2017201449A1. Chemical & Physical Properties Molecular Formula C6H13NO4 Exact Mass 163.084457 PSA 81.78000 LogP -1.59 Index of Refraction 1.467 InChIKey RUVRGYVESPRHSZ-UHFFFAOYSA-N SMILES NCCOCCOCC(=O)O Safety Information HS Code 2922509090 Synthetic Route Total: 1 Page 2-(2-(2-(dibenz... CAS#:166108-70-9 8-amino-3,6-dio... CAS#:134978-97-5 Literature: Organic Letters, , vol. 7, # 9 p. 1699 - 1702 CAS#:882518-90-3 8-amino-3,6-dio... CAS#:134978-97-5 Literature: Organic and Biomolecular Chemistry, , vol. 6, # 17 p. 3065 - 3078 Fmoc-8-amino-3,... CAS#:166108-71-0 8-amino-3,6-dio... CAS#:134978-97-5 Precursor & DownStream Precursor 2 CAS#:882518-90-3 CAS#:166108-71-0 Fmoc-8-amino-3,... DownStream 1 CAS#:166108-71-0 Fmoc-8-amino-3,... |
| Tax Rebate | 13.0% |
| Supervision | A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
| Inspection | R. Hygiene supervision and inspection of imported food S. Hygiene supervision and inspection of exported food |
| Transport Info | Product name: Supervision conditions A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
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