CAS Number1722-62-9
Synonyms(±)-1-Methyl-2',6'-pipecoloxylidide monohydrochloride; Mepivacaine hydrochloride; Mepivastesin; N-(2,6-dimethylphenyl)-1-methylpiperidine-2-carboxamide,hydrochloride; (±)-N-(2,6-Dimethylphenyl)-1-methylpiperidine-2-carboxamide Hydrochloride; Scandicain; 1-Methyl-2',6'-pipecoloxylidide hydrochloride; Carbocaina; N-(2,6-diméthylphényl)-1-méthylpipéridine-2-carboxamide chlorhydrate; 1-Methyl-2',6'-pipecoloxylidide monohydrochloride; N-(2,6-Dimethylphenyl)-1-methyl-2-piperidinecarboxamide Hydrochloride; Mepivicaine hydrochloride; N-(2,6-dimethylphenyl)-1-methylpiperidine-2-carboxamide hydrochloride; Mepivacaine HCL; N-(2,6-Dimethylphenyl)-1-methylpiperidin-2-carboxamidhydrochlorid; N-(2,6-Dimethylphenyl)-1-methylpiperidine-2-carboxamide hydrochloride (1:1); N-(2,6-Dimethylphenyl)-1-methyl-2-pi
Molecular FormulaC15H23ClN2O
Molecular Weight282.81
Purity98%
Boiling Point383.1ºC at 760 mmHg
Melting Point255-257ºC (dec.)
AppearanceWhite or off-white crystalline powder
EINECS217-023-9
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 1722-62-9 |
| Catalog No. | 2A-9011339 |
| Chinese Name | 盐酸甲哌卡因 |
| Synonyms | (±)-1-Methyl-2',6'-pipecoloxylidide monohydrochloride; Mepivacaine hydrochloride; Mepivastesin; N-(2,6-dimethylphenyl)-1-methylpiperidine-2-carboxamide,hydrochloride; (±)-N-(2,6-Dimethylphenyl)-1-methylpiperidine-2-carboxamide Hydrochloride; Scandicain; 1-Methyl-2',6'-pipecoloxylidide hydrochloride; Carbocaina; N-(2,6-diméthylphényl)-1-méthylpipéridine-2-carboxamide chlorhydrate; 1-Methyl-2',6'-pipecoloxylidide monohydrochloride; N-(2,6-Dimethylphenyl)-1-methyl-2-piperidinecarboxamide Hydrochloride; Mepivicaine hydrochloride; N-(2,6-dimethylphenyl)-1-methylpiperidine-2-carboxamide hydrochloride; Mepivacaine HCL; N-(2,6-Dimethylphenyl)-1-methylpiperidin-2-carboxamidhydrochlorid; N-(2,6-Dimethylphenyl)-1-methylpiperidine-2-carboxamide hydrochloride (1:1); N-(2,6-Dimethylphenyl)-1-methyl-2-pi |
| Molecular Formula | C15H23ClN2O |
| Molecular Weight | 282.81 |
| Purity | 98 |
| Boiling Point | 383.1ºC at 760 mmHg |
| Melting Point | 255-257ºC (dec.) |
| Appearance | White or off-white crystalline powder |
| Water Solubility | Water solubility: soluble; soluble in: methanol |
| Storage Condition | Warehouse low temperature ventilation and drying |
| Application | Mepivacaine hydrochloride has a local anesthetic effect. |
| EINECS | 217-023-9 |
| HTC | 2933399090 |
| MDL Number | MFCD00144738 |
| SMILES | CN1CCCCC1C(NC2=C(C)C=CC=C2C)=O.Cl |
| InChI | 1S/C15H22N2O.ClH/c1-11-7-6-8-12(2)14(11)16-15(18)13-9-4-5-10-17(13)3;/h6-8,13H,4-5,9-10H2,1-3H3,(H,16,18);1H |
| InChI Key | RETIMRUQNCDCQB-UHFFFAOYSA-N |
| NACRES Code | NA.24 |
| UNSPSC | 41116107 |
| Hazard Symbols | Transport |
| MSDS | msds/11339_1_1722_62_9.pdf |
| Bioactivity | Mepivacaine is a tertiary amine used as a local anesthetic.Target: Sodium ChannelMepivacaine is a local anesthetic of the amide type. Mepivacaine has a reasonably rapid onset (more rapid than that of procaine) and medium duration of action (shorter than that of procaine). Mepivacaine is used in any infiltration and regional anesthesia. It is supplied as the hydrochloride salt of the racemate [1]. Mepivacaine displayed a preferential use-dependent block of Na(v)1.8, S(-)-bupivacaine displayed a preference for TTXs Na(+) channels [2]. Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Neurological Disease Natural Products >> Others References [1]. Burm, A.G., et al., Pharmacokinetics of the enantiomers of mepivacaine after intravenous administration of the racemate in volunteers. Anesth Analg, 1997. 84(1): p. 85-9. [2]. Leffler, A., J. Reckzeh, and C. Nau, Block of sensory neuronal Na+ channels by the secreolytic ambroxol is associated with an interaction with local anesthetic binding sites. Eur J Pharmacol, 2010. 630(1-3): p. 19-28. Chemical & Physical Properties Boiling Point 383.1ºC at 760 mmHg Melting Point 255-257ºC (dec.) Molecular Formula C15H23ClN2O Molecular Weight 282.809 Flash Point 185.5ºC Exact Mass 282.149902 PSA 32.34000 LogP 3.53910 Vapour Pressure 4.52E-06mmHg at 25°C InChIKey RETIMRUQNCDCQB-UHFFFAOYSA-N SMILES Cc1cccc(C)c1NC(=O)C1CCCCN1C.Cl |
| Use of | Mepivacaine is a tertiary amine used as a local anesthetic.Target: Sodium ChannelMepivacaine is a local anesthetic of the amide type. Mepivacaine has a reasonably rapid onset (more rapid than that of procaine) and medium duration of action (shorter than that of procaine). Mepivacaine is used in any infiltration and regional anesthesia. It is supplied as the hydrochloride salt of the racemate [1]. Mepivacaine displayed a preferential use-dependent block of Na(v)1.8, S(-)-bupivacaine displayed a preference for TTXs Na(+) channels [2]. Properties Articles35 Name mepivacaine hydrochloride Synonym More Synonyms Mepivacaine hydrochloride Biological Activity Description Mepivacaine is a tertiary amine used as a local anesthetic.Target: Sodium ChannelMepivacaine is a local anesthetic of the amide type. Mepivacaine has a reasonably rapid onset (more rapid than that of procaine) and medium duration of action (shorter than that of procaine). Mepivacaine is used in any infiltration and regional anesthesia. It is supplied as the hydrochloride salt of the racemate [1]. Mepivacaine displayed a preferential use-dependent block of Na(v)1.8, S(-)-bupivacaine displayed a preference for TTXs Na(+) channels [2]. Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Research Areas >> Neurological Disease Natural Products >> Others References [1]. Burm, A.G., et al., Pharmacokinetics of the enantiomers of mepivacaine after intravenous administration of the racemate in volunteers. Anesth Analg, 1997. 84(1): p. 85-9. [2]. Leffler, A., J. Reckzeh, and C. Nau, Block of sensory neuronal Na+ channels by the secreolytic ambroxol is associated with an interaction with local anesthetic binding sites. Eur J Pharmacol, 2010. 630(1-3): p. 19-28. Chemical & Physical Properties Exact Mass 282.149902 PSA 32.34000 LogP 3.53910 InChIKey RETIMRUQNCDCQB-UHFFFAOYSA-N |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Shipping Name: UN |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 United Nations shipping name European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Danger Regulations: No International Maritime Danger Regulations International Air Transport Danger Regulations: No Marine pollutants (yes/no): No 14.6 Special reminder to users No data available |
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