CAS Number18524-94-2
Synonyms7-HYDROXY-6-DESOXYVERBENALIN; Loganoside; Cuchiloside; LOGANINE; Loganin; MFCD00075645; loganic acid methyl ester; Loganin, loganoside; Meliatin; EINECS 242-398-0
Molecular FormulaC17H26O10
Molecular Weight390.38
Purity≥97.0 (HPLC)%
Density1.5±0.1 g/cm3
Boiling Point608.8±55.0 °C at 760 mmHg
Melting Point222°C
Appearancewhite powder
EINECS242-398-0
Symbol
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| Chemical & Physical Properties | |
|---|---|
| CAS Number | 18524-94-2 |
| Catalog No. | 2A-9011215 |
| Chinese Name | 马钱苷； 番木鳖苷 |
| Synonyms | 7-HYDROXY-6-DESOXYVERBENALIN; Loganoside; Cuchiloside; LOGANINE; Loganin; MFCD00075645; loganic acid methyl ester; Loganin, loganoside; Meliatin; EINECS 242-398-0 |
| Molecular Formula | C17H26O10 |
| Molecular Weight | 390.38 |
| Purity | ≥97.0 (HPLC) |
| Density | 1.5±0.1 g/cm3 |
| Boiling Point | 608.8±55.0 °C at 760 mmHg |
| Melting Point | 222°C |
| Appearance | white powder |
| Water Solubility | Water solubility: completely soluble; insoluble: a |
| Storage Condition | Room Temperature |
| Application | Loganin is the main iridoid glycoside compound in Cornus officinalis and has anti-inflammatory and anti-shock effects. |
| EINECS | 242-398-0 |
| PubChem ID | 329755352 |
| MDL Number | MFCD00075645 |
| SMILES | COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]3[C@@H](C)[C@@H](O)C[C@H]13 |
| InChI | 1S/C17H26O10/c1-6-9(19)3-7-8(15(23)24-2)5-25-16(11(6)7)27-17-14(22)13(21)12(20)10(4-18)26-17/h5-7,9-14,16-22H,3-4H2,1-2H3/t6-,7+,9-,10+,11+,12+,13-,14+,16-,17-/m0/s1 |
| InChI Key | AMBQHHVBBHTQBF-UOUCRYGSSA-N |
| Beilstein/REAXYS | 55724 |
| NACRES Code | NA.24 |
| UNSPSC | 85151701 |
| Hazard Symbols | Transport |
| MSDS | msds/11215_1_18524_94_2.pdf |
| Bioactivity | Loganin, a major iridoid glycoside obtained from Corni fructus, has been shown to have anti-inflammatory and anti-shock effects. Loganin exhibits an anti-inflammatory effect in cases of AP and its pulmonary complications through inhibition of NF-κB activation. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Others Natural Products >> Terpenoids and Glycosides References [1]. Kim MJ, et al. Loganin protects against pancreatitis by inhibiting NF-κB activation. Eur J Pharmacol. 2015 Oct 15;765:541-50. [2]. Tsai WH, et al. Ba-Wei-Di-Huang-Wan through its active ingredient loganin counteracts substance P-enhanced NF-κB/ICAM-1 signaling in rats with bladder hyperactivity. Neurourol Urodyn. 2015 Aug 19. Chemical & Physical Properties Density 1.5±0.1 g/cm3 Boiling Point 608.8±55.0 °C at 760 mmHg Melting Point 222°C Molecular Formula C17H26O10 Molecular Weight 390.382 Flash Point 217.9±25.0 °C Exact Mass 390.152588 PSA 155.14000 LogP -2.73 Vapour Pressure 0.0±4.0 mmHg at 25°C Index of Refraction 1.600 InChIKey AMBQHHVBBHTQBF-UOUCRYGSSA-N SMILES COC(=O)C1=COC(OC2OC(CO)C(O)C(O)C2O)C2C1CC(O)C2C |
| Use of | Loganin, a major iridoid glycoside obtained from Corni fructus, has been shown to have anti-inflammatory and anti-shock effects. Loganin exhibits an anti-inflammatory effect in cases of AP and its pulmonary complications through inhibition of NF-κB activation. Properties Articles34 Name loganin Synonym More Synonyms Loganin Biological Activity Description Loganin, a major iridoid glycoside obtained from Corni fructus, has been shown to have anti-inflammatory and anti-shock effects. Loganin exhibits an anti-inflammatory effect in cases of AP and its pulmonary complications through inhibition of NF-κB activation. Related Catalog Signaling Pathways >> Others >> Others Research Areas >> Others Natural Products >> Terpenoids and Glycosides References [1]. Kim MJ, et al. Loganin protects against pancreatitis by inhibiting NF-κB activation. Eur J Pharmacol. 2015 Oct 15;765:541-50. [2]. Tsai WH, et al. Ba-Wei-Di-Huang-Wan through its active ingredient loganin counteracts substance P-enhanced NF-κB/ICAM-1 signaling in rats with bladder hyperactivity. Neurourol Urodyn. 2015 Aug 19. Chemical & Physical Properties Molecular Formula C17H26O10 Exact Mass 390.152588 PSA 155.14000 LogP -2.73 Index of Refraction 1.600 InChIKey AMBQHHVBBHTQBF-UOUCRYGSSA-N |
| Transport Info | Product name: Purity: 98.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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