![2,3-DIMETHOXY-6,6-DIMETHYL-5,6-DIHYDROBENZO[7,8]INDOLIZINO[2,3-B]QUINOXALINE structure, CAS 163769-88-8](/structures/120000/111138_1_163769_88_8.png)
CAS Number163769-88-8
SynonymsTocris-1675; 2,3-Dimethoxy-6,6-dimethyl-5,6-dihydrobenzo[7,8]indolizino[2,3-b]quinoxaline; Bio-0867; YM-90709
Molecular FormulaC22H21O2N3
Molecular Weight359.43
Purity96+%
Density1.3±0.1 g/cm3
Boiling Point579.6±50.0 °C at 760 mmHg
Appearancepowder
EINECS0
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 163769-88-8 |
| Catalog No. | 2A-0111138 |
| Chinese Name | YM-90709 |
| Synonyms | Tocris-1675; 2,3-Dimethoxy-6,6-dimethyl-5,6-dihydrobenzo[7,8]indolizino[2,3-b]quinoxaline; Bio-0867; YM-90709 |
| Molecular Formula | C22H21O2N3 |
| Molecular Weight | 359.43 |
| Purity | 96+ |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 579.6±50.0 °C at 760 mmHg |
| Appearance | powder |
| Storage Condition | -20℃ |
| Application | YM-90709 is a new antagonist that inhibits the binding of IL-5 to IL-5 receptors. |
| EINECS | 0 |
| HTC | 2933990090 |
| UN(IATA) | 0 |
| MDL Number | MFCD00354370 |
| SMILES | COc1cc2c(cc1OC)-c1cc3nc4ccccc4nc3n1C(C)(C)C2 |
| InChI | InChI=1S/C22H21N3O2/c1-22(2)12-13-9-19(26-3)20(27-4)10-14(13)18-11-17-21(25(18)22)24-16-8-6-5-7-15(16)23-17/h5-11H,12H2,1-4H3 |
| InChI Key | HIXSPVQXXDULHS-UHFFFAOYSA-N |
| Use of | Properties Name ym 90709 Synonym More Synonyms YM-90709 Biological Activity Related Catalog Signaling Pathways >> Immunology/Inflammation >> Interleukin Related Research Areas >> Inflammation/Immunology References [1]. Morokata T, et al. Characterization of YM-90709 as a novel antagonist which inhibits the binding of interleukin-5 to interleukin-5 receptor. Int Immunopharmacol. 2002 Nov;2(12):1693-702. [3]. Morokata T, et al. Effect of a novel interleukin-5 receptor antagonist, YM-90709 (2,3-dimethoxy-6,6-dimethyl-5,6-dihydrobenzo[7,8]indolizino[2,3-b]quinoxaline), on antigen-induced airway inflammation in BN rats. Int Immunopharmacol. 2004 Jul;4(7):873-83. Chemical & Physical Properties Molecular Formula C22H21N3O2 Exact Mass 359.163391 PSA 49.17000 Index of Refraction 1.666 InChIKey HIXSPVQXXDULHS-UHFFFAOYSA-N Storage condition -20℃ Safety Information HS Code 2933990090 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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