CAS Number13887-98-4
Synonyms2,2'-[Oxybis(2,1-ethanediyloxy)]diacetic acid; 2-[2-[2-(carboxymethoxy)ethoxy]ethoxy]acetic acid; 2,2'-[Oxybis(ethane-2,1-diyloxy)]diacetic acid
Molecular FormulaC8H14O7
Molecular Weight222.19
Purity96+%
Density1.3±0.1 g/cm3
Boiling Point443.7±30.0 °C at 760 mmHg
EINECS237-655-9
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 13887-98-4 |
| Catalog No. | 2A-0110331 |
| Chinese Name | 3,6,9-三噁十一烷二酸 |
| Synonyms | 2,2'-[Oxybis(2,1-ethanediyloxy)]diacetic acid; 2-[2-[2-(carboxymethoxy)ethoxy]ethoxy]acetic acid; 2,2'-[Oxybis(ethane-2,1-diyloxy)]diacetic acid |
| Molecular Formula | C8H14O7 |
| Molecular Weight | 222.19 |
| Purity | 96+ |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 443.7±30.0 °C at 760 mmHg |
| Storage Condition | room temperature |
| Packaging | III |
| Application | 369-Trioxaundanedioic Acid is a PROTAC linker, belonging to the PEG class. Can be used to synthesize PROTAC molecules. |
| EINECS | 237-655-9 |
| HTC | 2918990090 |
| UN(IATA) | 0 |
| PubChem ID | 57653473 |
| MDL Number | MFCD00044099 |
| SMILES | O=C(O)COCCOCCOCC(=O)O |
| InChI | InChI=1S/C8H14O7/c9-7(10)5-14-3-1-13-2-4-15-6-8(11)12/h1-6H2,(H,9,10)(H,11,12) |
| InChI Key | HJZZQNLKBWJYPD-UHFFFAOYSA-N |
| Beilstein/REAXYS | 1962084 |
| NACRES Code | NA.22 |
| UNSPSC | 12352106 |
| Use of | 369-Trioxaundecanedioic Acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Properties Name 3,6,9-Trioxaundecanedioic acid Synonym More Synonyms 3,6,9-Trioxaundecanedioic acid Biological Activity Description 369-Trioxaundecanedioic Acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Related Catalog Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. References [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 Chemical & Physical Properties Molecular Formula C8H14O7 Exact Mass 222.073959 PSA 102.29000 LogP -1.96 Index of Refraction 1.474 InChIKey HJZZQNLKBWJYPD-UHFFFAOYSA-N SMILES O=C(O)COCCOCCOCC(=O)O Safety Information Hazard Codes Xi: Irritant; Risk Phrases 41 Safety Phrases 26-39 RIDADR UN 1760 Packaging Group III HS Code 2918990090 Synthetic Route Total: 1 Page 3,6,9,12-Tetrao... CAS#:211746-77-9 3,6,9-Trioxaund... CAS#:13887-98-4 Literature: Bright, Sandra A.; Brinko, Anne; Larsen, Maja Thim; Sinning, Steffen; Williams, D. Clive; Jensen, Henrik H. Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 5 p. 1220 - 1224 2,2'-((Oxybis(e... CAS#:112-60-7 Diglycolic acid CAS#:110-99-6 3,6-Dioxaoctane... CAS#:23243-68-7 3,6,9-Trioxaund... CAS#:13887-98-4 Literature: Tetrahedron, , vol. 38, # 22 p. 3299 - 3308 2,2'-((Oxybis(e... CAS#:112-60-7 3,6,9-Trioxaund... CAS#:13887-98-4 Literature: Tetrahedron, , vol. 38, # 14 p. 2055 - 2060 Precursor & DownStream Precursor 1 CAS#:112-60-7 2,2'-((Oxybis(e... DownStream 4 CAS#:31255-25-1 2,2'-[oxybis(et... CAS#:93274-34-1 1-(3,5-dimethyl... CAS#:60350-17-6 1,4,7-trioxa-10... CAS#:41775-36-4 1,4,7,13-Tetrao... |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 30.0% |
| Transport Info | Product name: Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
| Related Products in Specialty Chemicals | ||
|---|---|---|
| 2'-METHYL-[1,1'-BIPHENYL]-4-AMINE HYDROCHLORIDE | 811842-48-5 | 2A-0110289 |
| 2,1,3-BENZOTHIADIAZOL-5-AMINE | 874-37-3 | 2A-0110298 |
| 2,2'-((2-HYDROXY-5-METHYL-1,3-PHENYLENE)BIS(METHYLENE))BIS(4-METHYLPHENOL) | 1620-68-4 | 2A-0110319 |
| 2,2'-((5-AMINO-1-CARBOXYPENTYL)AZANEDIYL)DIACETIC ACID | 129179-17-5 | 2A-0110326 |
| 2,2'-((5-CARBOXY-4-(CARBOXYMETHYL)-3-CYANOTHIOPHEN-2-YL)AZANEDIYL)DIACETIC ACID | 135459-90-4 | 2A-0110327 |
| 2,2'-(1,2-PHENYLENEBIS(OXY))DIETHANAMINE | 42988-85-2 | 2A-0110336 |
| 2,2'-(1,3-PHENYLENE)BIS(1,1,1,3,3,3-HEXAFLUOROPROPAN-2-OL) | 802-93-7 | 2A-0110338 |
| 2,2'-(1,3-PHENYLENE)DIACETIC ACID | 19806-17-8 | 2A-0110340 |
| 2,2'-(1,4-PHENYLENE)BIS(1,1,1,3,3,3-HEXAFLUOROPROPAN-2-OL) | 1992-15-0 | 2A-0110342 |
| 2,2'-(1,4-PHENYLENE)BIS(BENZO[D]OXAZOL-5-AMINE) | 13752-53-9 | 2A-0110344 |
| Browse all Specialty Chemicals products » | ||
Phone:
630-322-8886
630-322-8887
Email:
Office Locations:
Chicago, IL, USA
San Francisco, CA, USA
EN
SDS