![11-(2-(4-(4-(DIETHYLAMINO)BUTYL)PIPERIDIN-1-YL)ACETYL)-5H-BENZO[E]PYRIDO[3,2-B][1,4]DIAZEPIN-6(11H)-ONE structure, CAS 123548-16-3](/structures/120000/109938_1_123548_16_3.png)
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 123548-16-3 |
| Catalog No. | 2A-0109938 |
| Chinese Name | 11-[[4-[4-(二乙基氨基)丁基]-1-哌啶基]乙酰基]-5,11-二氢-6H-吡啶并[2,3-b][1,4]苯并二氮杂卓-6-酮 |
| Synonyms | AQ-RA 741; Compstatin control peptide; AQ-RA-741BS |
| Molecular Formula | C27H37N5O2 |
| Molecular Weight | 638.80 |
| Purity | ≥98 (HPLC) |
| Density | 1.132g/cm3 |
| Boiling Point | 602.7ºC at 760mmHg |
| Appearance | powder |
| Application | AQ-RA 741 is a potent M 2 -selective antagonist. AQ-RA 741 inhibits vagal or agonist-induced bradycardia in rats, cats, and guinea pigs. AQ-RA 741 can be used in the study of bradycardia. |
| EINECS | 0 |
| HTC | 2933990090 |
| UN(IATA) | 0 |
| SMILES | N7(CCN(CC7)C)C1CCN(CC1)C(=O)c2cc(c(cc2)Nc3nc4[n](c6c([c]([n](c4cn3)C)=O)cccc6)C5CCCC5)OCC |
| InChI | 1S/C36H46N8O3/c1-4-47-32-23-25(34(45)43-17-15-26(16-18-43)42-21-19-40(2)20-22-42)13-14-29(32)38-36-37-24-31-33(39-36)44(27-9-5-6-10-27)30-12-8-7-11-28(30)35(46)41(31)3/h7-8,11-14,23-24,26-27H,4-6,9-10,15-22H2,1-3H3,(H,37,38,39) |
| InChI Key | XVBGRTMNFNMINE-UHFFFAOYSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| MSDS | msds/109938_1_123548_16_3.pdf |
| Use of | AQ-RA 741 is a potent and selective M 2 antagonist. AQ-RA 741 inhibits the vagally or agonist-induced bradycardia in rats, cats and guinea-pigs. AQ-RA 741 is used in bradycardiac disorders research[1]. Properties Name 11-[2-[4-[4-(diethylamino)butyl]piperidin-1-yl]acetyl]-5H-pyrido[2,3-b][1,4]benzodiazepin-6-one Synonym More Synonyms AQ-RA 741 Biological Activity Description AQ-RA 741 is a potent and selective M 2 antagonist. AQ-RA 741 inhibits the vagally or agonist-induced bradycardia in rats, cats and guinea-pigs. AQ-RA 741 is used in bradycardiac disorders research[1]. Related Catalog Signaling Pathways >> Neuronal Signaling >> mAChR Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> mAChR References [1]. Doods H, et al.Cardioselectivityof AQ-RA 741, a novel tricyclic antimuscarinic drug. Eur J Pharmacol. 1991 Jan3;192(1):147-52. Chemical & Physical Properties Molecular Formula C27H37N5O2 Exact Mass 463.29500 PSA 74.23000 LogP 4.24220 Index of Refraction 1.566 InChIKey BCUGCHZRMKTPMU-UHFFFAOYSA-N Safety Information HS Code 2933990090 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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