![1-ETHYL-1H-BENZO[D]IMIDAZOL-2(3H)-ONE structure, CAS 10045-45-1](/structures/120000/108729_1_10045_45_1.png)
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 10045-45-1 |
| Catalog No. | 2A-0108729 |
| Chinese Name | 1-乙基-1H-苯并[d]咪唑-2(3H)-酮 |
| Synonyms | EINECS 233-148-1; 1-Ethyl-1,3-dihydro-2H-benzimidazol-2-one |
| Molecular Formula | C9H10O1N2 |
| Molecular Weight | 162.19 |
| Purity | 96+ |
| Density | 1.161±0.06 g/cm3 |
| Melting Point | 122 ºC |
| Appearance | powder |
| Water Solubility | Slightly soluble (1.6 g/L) (25 ºC) |
| Storage Condition | Store at RT |
| Application | 1-EBIO is an activator of calcium-sensitive potassium channels. 1-EBIO is used to study the role of K+ channels in various physiological functions [1]. |
| EINECS | 0 |
| HTC | 2933990090 |
| UN(IATA) | 0 |
| MDL Number | MFCD00005715 |
| SMILES | CCn1c(=O)[nH]c2ccccc21 |
| InChI | InChI=1S/C9H10N2O/c1-2-11-8-6-4-3-5-7(8)10-9(11)12/h3-6H,2H2,1H3,(H,10,12) |
| InChI Key | CXUCKELNYMZTRT-UHFFFAOYSA-N |
| MSDS | msds/108729_1_10045_45_1.pdf |
| Bioactivity | 1-EBIO is an activator of Ca2+ sensitive K+ channels. 1-EBIO is used to study the role of K+ channels in diverse physiological functions[1]. Related Catalog Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel References [1]. Devor DC, et al. Modulation of Cl- secretion by benzimidazolones. I. Direct activation of a Ca(2+)-dependent K+ channel. Am J Physiol. 1996 Nov;271(5 Pt 1):L775-84. Chemical & Physical Properties Density 1.161±0.06 g/cm3 Melting Point 122 ºC Molecular Formula C9H10N2O Molecular Weight 162.189 Exact Mass 162.079315 PSA 37.79000 LogP 1.39 Appearance of Characters powder Index of Refraction 1.566 InChIKey CXUCKELNYMZTRT-UHFFFAOYSA-N SMILES CCn1c(=O)[nH]c2ccccc21 Storage condition Store at RT Water Solubility Slightly soluble (1.6 g/L) (25 ºC) |
| Use of | 1-EBIO is an activator of Ca2+ sensitive K+ channels. 1-EBIO is used to study the role of K+ channels in diverse physiological functions[1]. Properties Articles33 Name 1-Ethyl-1H-benzo[d]imidazol-2(3H)-one Synonym More Synonyms Biological Activity Description 1-EBIO is an activator of Ca2+ sensitive K+ channels. 1-EBIO is used to study the role of K+ channels in diverse physiological functions[1]. Related Catalog Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel References [1]. Devor DC, et al. Modulation of Cl- secretion by benzimidazolones. I. Direct activation of a Ca(2+)-dependent K+ channel. Am J Physiol. 1996 Nov;271(5 Pt 1):L775-84. Chemical & Physical Properties Molecular Formula C9H10N2O Exact Mass 162.079315 PSA 37.79000 Appearance of Characters powder Index of Refraction 1.566 InChIKey CXUCKELNYMZTRT-UHFFFAOYSA-N Storage condition Store at RT |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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