CAS Number66-84-2
SynonymsEINECS 200-638-1; MFCD00135831; Glucosamine (hydrochloride)
Molecular FormulaC6H14ClNO5
Molecular Weight215.63
Purity≥99 (HPLC)%
Boiling Point449.9ºC at 760 mmHg
Melting Point190-194 °C (dec.) (lit.)
Appearancepowder
EINECS200-638-1
Symbol
Signal WordWarning
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 66-84-2 |
| Catalog No. | 2A-9010762 |
| Chinese Name | 氨基葡萄糖盐酸盐 |
| Synonyms | EINECS 200-638-1; MFCD00135831; Glucosamine (hydrochloride) |
| Molecular Formula | C6H14ClNO5 |
| Molecular Weight | 215.63 |
| Purity | ≥99 (HPLC) |
| Boiling Point | 449.9ºC at 760 mmHg |
| Melting Point | 190-194 °C (dec.) (lit.) |
| Appearance | powder |
| Storage Condition | Store in inert gas; avoid moisture (moisture absor |
| Application | Glucosamine hydrochloride is a natural product. |
| EINECS | 200-638-1 |
| HTC | 2932999099 |
| PubChem ID | 24895187 |
| MDL Number | MFCD00135831 |
| SMILES | Cl.N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O |
| InChI | 1S/C6H13NO5.ClH/c7-3-5(10)4(9)2(1-8)12-6(3)11;/h2-6,8-11H,1,7H2;1H/t2-,3-,4-,5-,6?;/m1./s1 |
| InChI Key | QKPLRMLTKYXDST-NSEZLWDYSA-N |
| Beilstein/REAXYS | 4157370 |
| NACRES Code | NA.25 |
| UNSPSC | 12352201 |
| Hazard Symbols | Transport |
| MSDS | msds/10762_1_66_84_2.pdf |
| Bioactivity | Glucosamine (hydrochloride) is a natural product.IC50 value:Target:In vitro: Glucosamine hydrochloride exhibited dose-dependent DPPH antioxidant activity [1]. Short-term (4 h) glucosamine hydrochloride treatment inhibited HIF-1α at the protein level, decreased phosphorylation of p70S6K and S6, translation-related proteins [2]. In the obstructed kidneys and TGF-β1-treated renal cells, glucosamine hydrochloride significantly decreased renal expression of α-smooth muscle actin, collagen I, and fibronectin [3]. In vivo: Related Catalog Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> Metabolic Enzyme/Protease >> HIF/HIF Prolyl-Hydroxylase Research Areas >> Others Natural Products >> Saccharides and Glycosides References [1]. Jamialahmadi K, et al. Protective effects of glucosamine hydrochloride against free radical-induced erythrocytes damage. Environ Toxicol Pharmacol. 2014 Jul;38(1):212-9. [2]. Jo JR, et al. Short-term treatment with glucosamine hydrochloride specifically downregulates hypoxia-inducible factor-1α at the protein level in YD-8 human tongue cancer cells. Int J Oncol. 2014 May;44(5):1699-706. [3]. Park J, et al. Glucosamine hydrochloride exerts a protective effect against unilateral ureteral obstruction-induced renal fibrosis by attenuating TGF-β signaling. J Mol Med (Berl). 2013 Nov;91(11):1273-84. Chemical & Physical Properties Boiling Point 449.9ºC at 760 mmHg Melting Point 190-194ºC Molecular Formula C6H14ClNO5 Molecular Weight 215.632 Flash Point 225.9ºC Exact Mass 215.056046 PSA 124.01000 Index of Refraction 72 ° (C=1， H2O) |
| Use of | Glucosamine (hydrochloride) is a natural product.IC50 value:Target:In vitro: Glucosamine hydrochloride exhibited dose-dependent DPPH antioxidant activity [1]. Short-term (4 h) glucosamine hydrochloride treatment inhibited HIF-1α at the protein level, decreased phosphorylation of p70S6K and S6, translation-related proteins [2]. In the obstructed kidneys and TGF-β1-treated renal cells, glucosamine hydrochloride significantly decreased renal expression of α-smooth muscle actin, collagen I, and fibronectin [3]. In vivo: Properties Articles20 Name D-Glucosamine hydrochloride Synonym More Synonyms D-Glucosamine hydrochloride Biological Activity Description Glucosamine (hydrochloride) is a natural product.IC50 value:Target:In vitro: Glucosamine hydrochloride exhibited dose-dependent DPPH antioxidant activity [1]. Short-term (4 h) glucosamine hydrochloride treatment inhibited HIF-1α at the protein level, decreased phosphorylation of p70S6K and S6, translation-related proteins [2]. In the obstructed kidneys and TGF-β1-treated renal cells, glucosamine hydrochloride significantly decreased renal expression of α-smooth muscle actin, collagen I, and fibronectin [3]. In vivo: Related Catalog Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> Metabolic Enzyme/Protease >> HIF/HIF Prolyl-Hydroxylase Research Areas >> Others Natural Products >> Saccharides and Glycosides References [1]. Jamialahmadi K, et al. Protective effects of glucosamine hydrochloride against free radical-induced erythrocytes damage. Environ Toxicol Pharmacol. 2014 Jul;38(1):212-9. [2]. Jo JR, et al. Short-term treatment with glucosamine hydrochloride specifically downregulates hypoxia-inducible factor-1α at the protein level in YD-8 human tongue cancer cells. Int J Oncol. 2014 May;44(5):1699-706. [3]. Park J, et al. Glucosamine hydrochloride exerts a protective effect against unilateral ureteral obstruction-induced renal fibrosis by attenuating TGF-β signaling. J Mol Med (Berl). 2013 Nov;91(11):1273-84. Chemical & Physical Properties Exact Mass 215.056046 PSA 124.01000 |
| Tax Rebate | 9.0% |
| Supervision | None MFN tariff: 6.5% Ordinary tariff: 30.0% |
| Transport Info | Product name: Purity: 0.0% |
| MSDS Transport Info | Module 14. Shipping information 14.1 UN dangerous goods number European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.2 Names specified by the United Nations (UN) European Land Transport Dangerous Regulations: Non-dangerous goods IMDG Code: Non-dangerous goods International air transport dangerous goods regulations: non-dangerous goods 14.3 Transport hazard categories European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.4 Package group European Land Transport Dangerous Regulations: -International Maritime Dangerous Regulations: -International Air Transport Dangerous Regulations: - 14.5 Environmental hazards European Land Transport Dangerous Regulations: No International Maritime Transport Dangerous Regulations Maritime Pollutants: No International Air Transport Risk Regulations: No 14.6 Special reminder to users No data available |
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