
CAS Number663921-15-1
SynonymsAmbotzPEG1370; Amino-PEG4-acid; 15-amino-4,7,10,13-tetraoxapentadecanoic acid; 1-Amino-3,6,9,12-tetraoxapentadecan-15-oic acid; H2N-PEG4-COOH
Molecular FormulaC11H23O6N1
Molecular Weight265.31
Purity96+%
Density1.1±0.1 g/cm3
Boiling Point409.6±40.0 °C at 760 mmHg
EINECS0
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 663921-15-1 |
| Catalog No. | 2A-0107201 |
| Chinese Name | α-胺-ω-丙酸四甘醇 |
| Synonyms | AmbotzPEG1370; Amino-PEG4-acid; 15-amino-4,7,10,13-tetraoxapentadecanoic acid; 1-Amino-3,6,9,12-tetraoxapentadecan-15-oic acid; H2N-PEG4-COOH |
| Molecular Formula | C11H23O6N1 |
| Molecular Weight | 265.31 |
| Purity | 96+ |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 409.6±40.0 °C at 760 mmHg |
| Storage Condition | -20°C |
| Application | NH2-PEG4-CH2CH2COOH is a degradable 4-unit PEG-based ADC linker for the synthesis of antibody drug conjugates (ADCs). |
| EINECS | 0 |
| HTC | 2922499990 |
| UN(IATA) | 0 |
| MDL Number | MFCD11041129 |
| SMILES | NCCOCCOCCOCCOCCC(=O)O |
| InChI Key | DKUZHSDZSMQOGQ-UHFFFAOYSA-N |
| MSDS | msds/107201_1_663921_15_1.pdf |
| Bioactivity | NH2-PEG4-CH2CH2COOH is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Related Catalog Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker Target Cleavable In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. References [1]. Hans-Georg Lerchen, et al. Antibody drug conjugates (adcs) having enzymatically cleavable groups. WO2018114578A1. Chemical & Physical Properties Density 1.1±0.1 g/cm3 Boiling Point 409.6±40.0 °C at 760 mmHg Molecular Formula C11H23NO6 Molecular Weight 265.303 Flash Point 201.5±27.3 °C Exact Mass 265.152527 PSA 100.24000 LogP -1.92 Vapour Pressure 0.0±2.1 mmHg at 25°C Index of Refraction 1.469 InChIKey DKUZHSDZSMQOGQ-UHFFFAOYSA-N SMILES NCCOCCOCCOCCOCCC(=O)O Storage condition -20°C |
| Use of | Properties Name 3-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]propanoic acid Synonym More Synonyms Related Catalog Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. References [1]. Hans-Georg Lerchen, et al. Antibody drug conjugates (adcs) having enzymatically cleavable groups. WO2018114578A1. Chemical & Physical Properties Molecular Formula C11H23NO6 Exact Mass 265.152527 PSA 100.24000 LogP -1.92 Index of Refraction 1.469 InChIKey DKUZHSDZSMQOGQ-UHFFFAOYSA-N SMILES NCCOCCOCCOCCOCCC(=O)O |
| Tax Rebate | 9.0% |
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| Inspection | P. Quarantine of entry animals, plants, and animal and plant products Q. Quarantine of exit animals, plants, and animal and plant products R. Hygiene supervision and inspection of imported food S. Hyg |
| Transport Info | Product name: Supervision conditions A. Customs clearance form for inbound goods B. Customs clearance form for outbound goods |
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