
| Chemical & Physical Properties | |
|---|---|
| CAS Number | 119431-25-3 |
| Catalog No. | 2A-0105583 |
| Chinese Name | 依利罗地 |
| Synonyms | eliprodil |
| Molecular Formula | C20H23ClFNO |
| Molecular Weight | 347.85 |
| Purity | ≥98 (HPLC) |
| Density | 1.205 g/cm3 |
| Boiling Point | 474.1ºC at 760 mmHg |
| Appearance | powder |
| Storage Condition | 2-8°C |
| Application | Eliprodil (SL-820715) is a highly selective inhibitor of NR2B-NMDA receptors with an IC50 value of 1uM and has weak effects on NR2A- and NR2C-NMDA receptors. |
| EINECS | 0 |
| HTC | 2933399090 |
| UN(IATA) | 0 |
| PubChem ID | 24277709 |
| MDL Number | MFCD00866651 |
| SMILES | OC(CN1CCC(CC1)Cc2ccc(F)cc2)c3ccc(Cl)cc3 |
| InChI | 1S/C20H23ClFNO/c21-18-5-3-17(4-6-18)20(24)14-23-11-9-16(10-12-23)13-15-1-7-19(22)8-2-15/h1-8,16,20,24H,9-14H2 |
| InChI Key | GGUSQTSTQSHJAH-UHFFFAOYSA-N |
| NACRES Code | NA.77 |
| UNSPSC | 12352200 |
| MSDS | msds/105583_1_119431_25_3.pdf |
| Use of | Properties Articles24 Name Eliprodil,α-(4-Chlorophenyl)-4-[(4-fluorophenyl)methyl]-1-piperidineethanol Synonym More Synonyms Eliprodil Biological Activity Related Catalog Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease References [1]. Bath CP, et al. The effects of ifenprodil and eliprodil on voltage-dependent Ca2+ channels and in gerbil global cerebral ischaemia. Eur J Pharmacol. 1996 Mar 28;299(1-3):103-12. [2]. Lengyel C, et al. Effect of a neuroprotective drug, eliprodil on cardiac repolarisation: importance of the decreased repolarisation reserve in the development of proarrhythmic risk. Br J Pharmacol. 2004 Sep;143(1):152-8. Chemical & Physical Properties Exact Mass 347.14500 PSA 23.47000 LogP 4.40510 Index of Refraction 1.58 InChIKey GGUSQTSTQSHJAH-UHFFFAOYSA-N Safety Information GHS07, GHS09 Signal Word Warning Hazard Statements H319-H410 Precautionary Statements P273-P305 + P351 + P338-P501 Personal Protective Equipment Eyeshields;Gloves Hazard Codes N: Dangerous for the environment; Safety Phrases 60-61 HS Code 2933399090 |
| Tax Rebate | 13.0% |
| Supervision | None. MFN tariff: 6.5%. Ordinary tariff: 20.0% |
| Transport Info | Product name: Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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